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REVIEW : TINGKAT EFEKTIVITAS IMUNISASI CAMPAK DAN FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN CAMPAK DI INDONESIA Faizal Auladi Rivianto; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.754 KB) | DOI: 10.36490/journal-jps.com.v6i1.3

Abstract

Measles is a disease caused by Morbillivirus measles virus which is an RNA virus from the Paramyxovirus group. This disease attacks the respiratory and immune systems of a person and is contagious. Measles is easy to recognize because it has characteristic clinical symptoms and has become a universal disease. This makes measles a concern of various countries because the disease can cause death if not treated and prevented from spreading. The purpose of this study is to analyze the factors that can influence the incidence of measles in Indonesia by using a literature study in the last 6 years (2016-2022). The method used is a literature review which includes the literature search process, exclusion inclusion criteria and study selection and literature quality assessment. The total literature used is 14 samples of research articles. The results showed that there were various factors that influenced the incidence of measles, but the dominant factors influencing the level of knowledge of parents regarding measles immunization and measles immunization status. It is hoped that the public will gain insight regarding measles immunization and understand how to prevent measles and maintain a clean environment so that it does not become a breeding ground for disease
Molecular Docking Senyawa Yang Berpotensi Sebagai Antikanker Payudara: Literature Review Anisa Fauziah; Adelia Fatharani; Cindhy Maulida Nurawaliah; Faizal Auladi Rivianto; Irene Virda Sakina; Marsah Rahmawati; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (353.825 KB) | DOI: 10.36490/journal-jps.com.v6i2.34

Abstract

Cancer is a degenerative disease that has claimed many victims. Currently breast cancer is the second most common cancer that causes death after lung cancer and is the most common cancer suffered by women. Treatment of breast cancer is generally done with chemotherapy, radiotherapy, hormone therapy and surgery. Several synthetic drugs have been used to inhibit the growth of cancer cells. However, these drugs have dangerous side effects for the body so other alternatives are needed, including developing drugs derived from plants. To predict the activity of compounds from plants that have potential as anti-breast cancer, the molecular docking method was used. This review aims to inform compounds that have the potential as anti-breast cancer based on the results of molecular docking. The research method used was a literature study of 15 journals searched on the Google Scholar and Google databases related to molecular docking of breast anticancer compounds. The results of the review show that several compounds have the potential to inhibit breast cancer receptors including mangiferin compounds which are the best at inhibiting HER-2 receptors, quercetin glycoside compounds which are the best at inhibiting Bcl-2 receptors, quinine compounds which are the best at inhibiting ER-α receptors, compounds 6,7 -dihydro-17-hydroxyerisotrin is the best at inhibiting EGFR receptors, curcumin compounds are the best at inhibiting COX-2 receptors and eugenol compounds are the best at inhibiting ER-β receptors.