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All Journal Konselor Journal of Medicine and Health
Ryan Yudistiro, Ryan
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Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Generalized Lymphadenopathy due to Chronic Lymphocytic Leukemia (CLL) : 18F-FDG PET Imaging Hidayat, Basuki; Hutomo, Febby; Yudistiro, Ryan; Mulyanto, Ivana D.; Budiawan, Hendra; Masjhur, Johan S.
Journal of Medicine and Health Vol 1, No 3 (2016)
Publisher : Maranatha Christian University

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Abstract

Lymphadenopaty is a common clinical finding with a broad differential diagnosis, withCarcinoma of Unknown Primary (CUP) as one of it’s most common causes. Flourine-18 fluoro-2 deoxy glucose (18F- FDG) positron emission tomography (PET) is a Nuclear Medicinescintigraphy procedure commonly used to localize suspected a primary lesion by depicting ametabolic status. However, in the expertise of 18F FDG PET study, clinical finding andepidemiologic data must be considered to get a better conclusion. We describe 18F-FDG PETstudy in the presence of generalized lymphadenopathy due to chronic lymphocytic leukemia(CLL), a rare disease which is initially suspected of having CUP.Keywords: 18F-FDG PET, lymphadenopathy, lymphoma, leukemia
A study of brainspotting therapy in PTSD using 18FDG brain PET scan to evaluate glucose metabolism changes Foo, Mariana; Yudistiro, Ryan
Konselor Vol 11, No 4 (2022): KONSELOR
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1183.844 KB) | DOI: 10.24036/02022114121548-0-00

Abstract

Post Traumatic Stress Disorder (PTSD)  is a psychiatric and neurological disorder characterized by repeating experiences, avoidance, and hyperarousal. Brainspotting therapy (BSP) is a new body and brain treatment that claims to be effective in treating trauma and  providing access to the brain. However, limited trials using neuroimaging have been done. A single-subject pretest-posttest design was applied in this study with two subjects (n = 1 PTSD; n = 1 Healthy Control; HC). Thirty sessions with online BSP were given to the PTSD subjects. 18FDG PET measurements and clinical assessment using HAM-A, DASS, and PCL-5 were taken for both subjects before and after treatment. The SDMAC value of brain 18FDG PET derived from NeuroQTMsoftware was used quantitatively between the PTSD and HC subjects to evaluate the glucose metabolism level of the mid-frontal cortex (MFC) and medial temporal cortex(MTC), which is associated with PTSD. Measurements taken post-treatment for clinical assessment exhibited a reduction in PTSD symptoms while PET scans demonstrated varied results. The findings of this study indicate that online BSP is effective for improving PTSD symptoms and has various effects on brain glucose metabolism. The limitations and suggestions of the study are discussed for further research.
Co-Authors Basuki Hidayat Febby Hutomo, Febby Foo, Mariana Hendra Budiawan, Hendra Ivana D. Mulyanto, Ivana D. Johan S. Masjhur, Johan S.