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Amrendra Kumar, Amrendra
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Medicine & Pharmacology

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Formulation and evaluation of extended release spheroids for antidepressant drug by MUPS Kumar, Amrendra; Singh, Vikram; Juyal, Divya; Rawat, Geeta
Journal of Applied Pharmaceutical Research Vol 2 No 4 (2014)
Publisher : Creative Pharma Assent

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Abstract

The extended release spheroids was Formulated using Ethyl Cellulose, Povidone and Triacetin as a Coating material and evaluated the effect of change in weight build up on drug release profile. Optimization of extended release coating by 19% build up of EC/PVP-K30 of formulation (F4), in which the formulation is formulated by Reservoir system and the drug release depends on coating thickness of EC/PVP-K30. As concentration of coating weight buildup increases. which increases the thickness of coating on the reservoir system hence release retarded and transformed into an extended release system. 
Formulation and evaluation of extended release spheroids for antidepressant drug by MUPS Kumar, Amrendra; Singh, Vikram; Juyal, Divya; Rawat, Geeta
Journal of Applied Pharmaceutical Research Vol. 2 No. 4 (2014)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.496 KB)

Abstract

The extended release spheroids was Formulated using Ethyl Cellulose, Povidone and Triacetin as a Coating material and evaluated the effect of change in weight build up on drug release profile. Optimization of extended release coating by 19% build up of EC/PVP-K30 of formulation (F4), in which the formulation is formulated by Reservoir system and the drug release depends on coating thickness of EC/PVP-K30. As concentration of coating weight buildup increases. which increases the thickness of coating on the reservoir system hence release retarded and transformed into an extended release system.
Co-Authors Divya Juyal, Divya Geeta Rawat, Geeta Vikram Singh, Vikram