Claim Missing Document
Check
Articles

Found 2 Documents
Search

Faktor Prognostik pada Efusi Pleura Ganas Berdasarkan Skor LENT di RSUP Prof. Dr. R. D. Kandou Manado Enika Tilaar; Adrian Tangkilisan; Christha Tamburian; Grace Korompis
Medical Scope Journal Vol. 5 No. 2 (2023): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v5i2.46618

Abstract

Abstract: As a complication of cancer, malignant pleural effusion (MPE) is related to varied life expectancy. LENT score is the first validated score in malignant pleural effusion. This study aimed to obtain factors affecting the MPE based on LENT score at Prof. Dr. R. D. Kandou Hospiptal, Manado. This was a prospective study with a cross sectional design Subjects were patients with MPE admitted to Prof Dr. R. D. Kandou from January to November 2022. The results obtained 30 MPE patients consisting of 50% males and 50% females with a mean age of 52 years. There were 22 patients with LDH level <1,500 IU/L dan eight patients with LDH level >1,500 IU/L. Based on ECOG score, there were three patients with score 1, seven patients with score 2, and 20 patients with score 3-4. There were 13 patients with NLR <9 and 17 patients with NLR >9. Lung cancer was the most common cancer causing MPE, followed by gynaecological cancer and breast cancer. Based on LENT score, there were 20 patients with high risk, 10 patients with moderate risk; no patients with low risk. In conclusion, LENT score can be used as prognostic score in patients with malignant pleural effusion. Keywords: malignant pleural effusion; LENT score; complication of cancer   Abstrak: Efusi pleura ganas (EPG) merupakan komplikasi dari kanker dan dihubungkan dengan dengan angka harapan hidup yang bervariasi. Skor LENT merupakan skor tervalidasi pertama yang digunakan pada efusi pleura ganas. Penelitian ini bertujuan untuk menggambarkan faktor-faktor yang berperan pada EPG berdasarkan skor LENT di RSUP Prof. Dr. R. D. Kandou Manado. Penelitian prospektif cross sectional dari pasien dengan EPG di RSUP Prof Dr. R. D. Kandou Manado (Januari hingga November 2022). Pada penelitian ini didapatkan 30 pasien EPG (50% laki-laki; 50% perempuan) dengan rerata usia 52 tahun. Terdapat 22 pasien dengan kadar LDH di bawah 1.500 IU/L dan delapan pasien dengan kadar LDH di atas 1.500 IU/L. Berdasarkan skor ECOG, terdapat 3 pasien dengan skor 1, 7 pasien dengan skor 2, dan 20 pasien dengan skor 3-4. Terdapat 13 pasien dengan nilai NLR di bawah 9 dan 17 pasien dengan nilai NLR di atas 9. Kanker paru merupakan tipe tumor paling sering menyebabkan efusi pleura ganas, diikuti kanker ginekologi dan kanker payudara. Berdasarkan skor LENT terdapat 20 pasien dengan resiko tinggi, 10 pasien dengan resiko sedang, dan tidak ada pasien dengan resiko rendah. Skor LENT berperan sebagai skor prognostik pada pasien dengan EPG. Kata kunci: efusi pleura ganas; skor LENT; komplikasi kanker
Liposarcoma of the Thyroid Gland: A Case Report Christian Manginstar; Marselus Merung; Denny Saleh; Leise Limpeleh; Enika Tilaar; Ridel Torar
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.51654

Abstract

Abstract: Liposarcoma is one of the most common soft tissue tumors in adults. Liposarcoma is usually found in retroperitoneal organs and extremities, but rarely in the thyroid gland. We presented a case of dedifferentiated liposarcoma in the thyroid gland. A 56-year-old woman with a history of a lump in her neck for ten years. Malignancy was suspected due to the local extension of the tumor, therefore, complete resection of the tumor was performed. Histopathological examination showed a dedifferentiated liposarcoma. Two months post-surgery, the patient suffered from lung and brain metastases and was treated with lenvatinib. The complaints reduced and there was no significant side effect during therapy. The treatments for liposarcoma are surgery, radiotherapy, chemotherapy, and targeted therapy. Surgery followed by radiotherapy and chemotherapy is the option in the treatment of liposarcoma. This patient underwent surgery with the histopathological result of dedifferentiated thyroid liposarcoma. In the nine-month follow-up of therapy, there were no complaint of the patient. In this case, dedifferentiated liposarcoma in the thyroid gland with metastases was treated surgically followed by lenvatinib administration gave satisfactory result. Keyword: liposarcoma; thyroid gland; dedifferentiated liposarcoma; malignant tumor