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Liposarcoma of the Thyroid Gland: A Case Report Christian Manginstar; Marselus Merung; Denny Saleh; Leise Limpeleh; Enika Tilaar; Ridel Torar
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.51654

Abstract

Abstract: Liposarcoma is one of the most common soft tissue tumors in adults. Liposarcoma is usually found in retroperitoneal organs and extremities, but rarely in the thyroid gland. We presented a case of dedifferentiated liposarcoma in the thyroid gland. A 56-year-old woman with a history of a lump in her neck for ten years. Malignancy was suspected due to the local extension of the tumor, therefore, complete resection of the tumor was performed. Histopathological examination showed a dedifferentiated liposarcoma. Two months post-surgery, the patient suffered from lung and brain metastases and was treated with lenvatinib. The complaints reduced and there was no significant side effect during therapy. The treatments for liposarcoma are surgery, radiotherapy, chemotherapy, and targeted therapy. Surgery followed by radiotherapy and chemotherapy is the option in the treatment of liposarcoma. This patient underwent surgery with the histopathological result of dedifferentiated thyroid liposarcoma. In the nine-month follow-up of therapy, there were no complaint of the patient. In this case, dedifferentiated liposarcoma in the thyroid gland with metastases was treated surgically followed by lenvatinib administration gave satisfactory result. Keyword: liposarcoma; thyroid gland; dedifferentiated liposarcoma; malignant tumor
Faktor Prediktor Terjadinya Delayed Hemothorax pada Pasien dengan Riwayat Trauma Tumpul Toraks di RSUP Prof Dr. R.D. Kandou Manado Gufi George Stefanus; Wega Sukanto; Adrian Tangkilisan; F. L. Fredrik G. Langi; Eko Prasetyo; Christha Tamburian; Denny Saleh
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 02 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i02.133

Abstract

Trauma toraks merupakan penyebab signifikan dari morbiditas dan mortalitas, terutama dalam konteks multitrauma, dengan dampak kematian berkisar antara 20% hingga 25%. Penelitian ini bertujuan untuk mengetahui faktor prediktor terjadinya delayed hemothorax pada pasien dengan riwayat trauma tumpul toraks di RSUP Prof. Dr. R.D. Kandou Manado. Metode yang di guanakan metode penelitian dengan pendekatan kohort retrospektif, dengan cara consecutive sampling, analisis data dengan analisis deskriptif. Adapun hasil penelitian, ditemukan bahwa faktor prediktor yang signifikan adalah adanya fraktur tulang iga, jumlah fraktur iga 3 atau lebih, dan lokasi fraktur tulang iga. Usia dan kejadian kontusio paru tidak ditemukan sebagai faktor prediktor yang signifikan. Hasil penelitian juga menunjukkan bahwa pasien yang memiliki fraktur pada tulang iga ke 10-12, 6-9, dan 3-5 memiliki risiko lebih tinggi untuk mengalami delayed hemothorax.