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All Journal JITK (Jurnal Ilmu Pengetahuan dan Komputer) INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY
Malika Zilda
Universitas Muhammadiyah Palembang
Computer Science & IT Health Professions Social Sciences

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DIABETIC RETINOPATHY SEVERITY CLASSIFICATION USING GAMMA CORRECTION-BASED IMAGE ENHANCEMENT AND BN-VGG ARCHITECTURE Indri Ramayanti; Karnadi; Septiani Nadra Indawaty; Muhammad Umar Abdussalam; Malika Zilda; Anita Desiani
JITK (Jurnal Ilmu Pengetahuan dan Teknologi Komputer) Vol. 11 No. 4 (2026): JITK Issue May 2026
Publisher : LPPM Nusa Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33480/jitk.v11i4.8094

Abstract

Diabetic retinopathy (DR) is a diabetes-related condition that can cause vision impairment or vision loss. Accurately identifying the level of DR from retinal fundus images is crucial for early detection. However, poor image quality often degrades classification performance. This study proposes an approach that integrates gamma correction-based image enhancement with a Batch Normalization–Visual Geometry Group (BN-VGG) architecture for multiclass DR severity classification. Gamma correction is applied to improve image contrast, while BN-VGG enhances training stability and feature representation. The proposed method categorizes DR into five classifications: normal, mild, moderate, severe, and proliferative. The enhanced images achieved PSNR of 30.85 and SSIM above 0.86, indicating improved visual quality. The model achieved accuracy at 0.97, sensitivity at 0.92, specificity at 0.98, F1-score at 0.92, Cohen's Kappa at 0.90, and G-Mean at 0.97. The innovative aspect of this study is the incorporation of gamma correction with BN-VGG architecture, demonstrating that image enhancement can significantly improve multiclass DR classification performance without increasing model complexity. The study's results indicate the proposed method's effectiveness for accurate & reliable DR severity classification
Spectroscopic characterization of rosella flower extract (Hibiscus sabdariffa L.) and its antibacterial activity against Enterobacter aerogenes in suspected typhoid cases Siti Rohani; Fadhil Rizki Martha; Trisnawati Mundijo; Yesi Astri; Malika Zilda; Agnes Melianti
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 7 No 1 (2025): Advances in Biomarkers, Therapeutics, and Probiotics: Recent Updates in Medical L
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v7i1.5577

Abstract

Typhoid, a serious bacterial disease, has spurred research into natural products like rosella (Hibiscus sabdariffa L.) for potential treatments. This study investigates the chemical components found in Rosella extract using spectroscopy approximation, assisted by Fourier transform infrared spectroscopy (FTIR) and Gas chromatography–mass spectrometry (GC–MS). The antibacterial activity of rosella extract on bacteria from stool cultures of suspected typhoid cases continues to be evaluated. The antibacterial experimental employed a post-test-only control group design, using 30 μg Chloramphenicol as a positive control, sterile distilled water as the negative control, rosella extract at concentrations of 25%, 50%, 75%, and 100% as the observed variable. Stool samples from typhoid patients were identified, and Enterobacter aerogenes were detected using VITEK®2 testing. Cultivated bacteria from the samples were tested to determine the antibacterial activity of the rosella extract. Phytochemical studies confirmed the presence of tannins, alkaloids, flavonoids, and saponins in the rosella extract. Additionally, the spectroscopic evaluation from FTIR and GC-MS showed the presence of chemical groups, including esters, aldehydes, and aromatics. Further clinical tests demonstrated antibacterial activity at the minimum inhibitory concentration. The results showed an increasing inhibition zone of bacterial growth, correlating with the increase in rosella extract concentration. Although the antibacterial activity of rosella extract was lower compared to commercial Chloramphenicol, this natural product has demonstrated antibacterial activity and shows potential as a candidate for future herbal medicine development.
Co-Authors Agnes Melianti Anita Desiani Fadhil Rizki Martha Indri Ramayanti Karnadi Muhammad Umar Abdussalam Septiani Nadra Indawaty Siti Rohani Trisnawati Trisnawati Yesi Astri