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All Journal International Review of Practical Innovation, Technology and Green Energy (IRPITAGE) KOLONI MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation
Aditya Candra
Universitas Abulyatama
Humanities Civil Engineering, Building, Construction & Architecture Dentistry Energy Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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PHYTOCHEMICAL SCREENING AND GC-MS ANALYSIS OF ETHANOLIC EXTRACT OF Chromolaena odorata LEAVES Aditya Candra; Tahara Dilla Santi; Ika Waraztuty; Syarifah Nora Andrianty; Andri; Said Aandy Saida
MEDALION Journal: Medical Research, Nursing, Health and Midwife Participation Vol. 7 No. 2 (2026): June
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chromolaena odorata leaves are empirically known to act as anti-inflammatory and other pharmacological effects. In this study, ethanol extracts from Chromolaena odorata leaves were analyzed using phytochemical screening and gas chromatography-mass spectrometry (GC-MS) to identify phytochemical constituents. Phytochemical tests showed the presence of flavonoids, alkaloids, tannins, saponins, and phenolics. GC-MS analysis of ethanol extracts from Chromolaena odorata leaves detected the presence of seven phytochemical compounds, namely Ethyl (E)-4-(2-phenylethylamino)but-2-enoate; 2h-pyran 2-(7-heptadecynyloxy) tetrahydro; 3,7,11-Trimethyldodeca-2,6,10-trienyl acetate; Bicyclo(3.1.1)heptane, 2,6,6-trimethyl-,(1alpha,2beta,5alpha)-11,13-Dimethyl-12-tetradecen-1-yl acetate; (2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecen-1-ol, and 9,12,15-Octadecatrienoic acid. This study identified several constituents that are biologically active compounds through GC-MS. These phytocompounds have potential as herbal medicines due to pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, antibacterial, and anticancer.
SOCIALIZATION AND GUIDANCE IN THE MAKING OF HERBAL SAUNAS IN ALUE DEAH TEUNGOH VILLAGE IN 2025 Tahara Dilla Santi; Aditya Candra; Naimah; Ika Waraztuty; Andri; Said Aandy Saida; Ns. Eka Oktarina Riani
International Review of Practical Innovation, Technology and Green Energy (IRPITAGE) Vol. 5 No. 3 (2025): November 2025 - February 2026
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.19464730

Abstract

The International Labor Organization (ILO) reports that 2 million people die in the workplace, one of the causes being overexertion. Herbal saunas are decoctions of plants with medicinal properties, including anti-fatigue. Warm steam applied to the skin helps dilate blood vessels, improving circulation. The purpose of this activity was to provide knowledge about various medicinal plants that can be used as herbal saunas and to provide community members with skills in making herbal saunas. The PKM method involved participation through outreach and mentoring women in preparing herbal saunas. The activity took place on July 27, 2025, in Alue Deah Teungoh Village, with 15 women participating in the Family Welfare Movement (PKK). The activity began with a pre-test and then a herbal sauna booklet. The results of this activity were an increase in the knowledge and skills of the PKK women, demonstrated by the resulting product, a dried herbal sauna packaged in a standing pouch. Participants were very enthusiastic about the training. The activity concluded with the use of herbal saunas, which were boiled in a steamer and the steam flowed into a portable sauna tent. Participants took turns using the sauna, which had been filled with the herbal sauna decoction.
Gambaran Tingkat Kecemasan Mahasiswa Dalam Menghadapi Mini-OSCE Di Fakultas Kedokteran Universitas Abulyatama Atika Humairah; Ratih Ayu Atika; Aditya Candra
KOLONI Vol. 5 No. 3 (2026): SEPTEMBER 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i3.1306

Abstract

Mini-Objective Structured Clinical Examination (Mini-OSCE) is one of the clinical skills assessment methods used in medical education, particularly to evaluate students' ability to apply knowledge, clinical skills, and communication in a structured manner. The implementation of the Mini-OSCE may become a source of psychological pressure for students because it requires them to demonstrate their competencies in an examination setting within a limited period of time. This condition may trigger anxiety at varying levels of severity and potentially affect students' readiness to undertake clinical skills examinations. This study aimed to describe the anxiety levels of students at the Faculty of Medicine, Abulyatama University, when facing the Mini-OSCE and to identify the distribution of anxiety levels based on academic cohorts. This study employed a quantitative descriptive design with a cross-sectional approach. The sample consisted of 120 students from the 2022, 2023, 2024, and 2025 cohorts, who were selected using a quota sampling technique. Data were collected using the Hamilton Anxiety Rating Scale (HARS) questionnaire distributed through Google Forms and analyzed using univariate analysis in the form of frequency and percentage distributions. The results showed that 41 respondents (34.2%) were classified as having no anxiety, 23 respondents (19.2%) experienced mild anxiety, 31 respondents (25.8%) experienced moderate anxiety, 23 respondents (19.2%) experienced severe anxiety, and 2 respondents (1.7%) experienced very severe anxiety. Overall, 79 students (65.8%) experienced anxiety at varying levels of severity. Based on academic cohorts, students from the 2025 cohort showed higher proportions of moderate and severe anxiety than students from the other cohorts. In conclusion, although the no-anxiety category represented the largest single proportion of respondents, anxiety was still experienced by the majority of respondents across varying levels of severity. These findings highlight the importance of improving academic preparedness, providing regular clinical skills practice and Mini-OSCE simulations, and strengthening students' anxiety management abilities as part of their preparation for clinical skills assessments.
Perbandingan Aktivitas Antibakteri Ekstrak Jahe Dan Antibiotik Kloramfenikol Terhadap Escherichia Coli Sarah Yunita; Aditya Candra; M. Syakir Marzuki
KOLONI Vol. 5 No. 3 (2026): SEPTEMBER 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i3.1407

Abstract

Escherichia coli is one of the pathogenic bacteria that can cause various infections and has the potential to develop resistance to antibiotics. This condition encourages the exploration of natural materials that may serve as alternative antibacterial agents. Ginger (Zingiber officinale) contains various secondary metabolites, such as flavonoids, phenolic compounds, terpenoids, and other active compounds, which potentially possess antibacterial activity. This study aimed to determine the antibacterial activity of ethanol extract of ginger against the growth of Escherichia coli and to compare its activity with the antibiotic chloramphenicol. This study was an experimental laboratory study using the disk diffusion (Kirby-Bauer) method. Ginger extract was obtained through maceration using 96% ethanol and was tested at concentrations of 25%, 50%, 75%, and 100%. The test bacterium used was Escherichia coli ATCC 25922. Chloramphenicol was used as a positive control, while distilled water was used as a negative control. Each treatment was performed in triplicate, and antibacterial activity was determined based on the diameter of the inhibition zone formed. The results showed that the ethanol extract of ginger was able to inhibit the growth of Escherichia coli at all tested concentrations. The mean inhibition zone diameters at concentrations of 25%, 50%, 75%, and 100% were 17.15 mm, 20.65 mm, 17.07 mm, and 15.66 mm, respectively. The highest antibacterial activity was observed at a concentration of 50%. Chloramphenicol produced a mean inhibition zone diameter of 37.00 mm, whereas the negative control produced a diameter of 6.00 mm. Based on these findings, it can be concluded that ginger ethanol extract has antibacterial activity against Escherichia coli, although its activity remains lower than that of chloramphenicol.
Co-Authors Andri Atika Humairah Ika Waraztuty M. Syakir Marzuki Naimah Ns. Eka Oktarina Riani Ratih Ayu Atika Said Aandy Saida Sarah Yunita Syarifah Nora Andrianty Tahara Dilla Santi