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GAMBARAN PERESEPAN OBAT PADA PASIEN DIARE DI PUSKESMAS JAMBI KECIL TAHUN 2020 Faila Sufa; Armaidi Darmawan; Nyimas Natasha Ayu Shafira; Rina Nofrienis; Erny Kusdiyah
Journal of Medical Studies Vol. 1 No. 2 (2021): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v1i2.16567

Abstract

ABSTRACT Background: Diarrhea remains a serious health problem since it is a leading cause of death. Improper treatments are the main cause of death from diarrhea. One of ways to prevent this is to use rational drugs, which can be assessed using WHO prescribing indicators. Objectives: This study aims to determine drug prescribing for diarrhea patients at the Jambi Kecil Health Center in 2020. Methods: A quantitative descriptive study with a sample of 115 prescriptions for diarrhea patients at the Jambi Kecil Health Center in 2020 (total sampling). Results: Diarrhea was highest in female (56,5%) and among 0-4 years old age group (34,8%), the most frequently prescribed antidiarrheal drugs was oral rehydration solution (15,2%), the average number of drugs prescribed was 3.37, the drugs prescribed by generic name was 94,1%, the encounters with an antibiotic prescribed was 42,6%, the encounters with an injection prescribed was 0%, the drugs prescribed from DOEN was 76,8%. Conclusions: Oral rehydration solutions were the most prescribed drugs, the percentage of drugs prescribed by generic name and injection were in accordance wtih WHO indicators, while the average number of drugs prescribed, the percentage of antibiotic, and drugs prescribed from DOEN were not in accordance with WHO indicator standards. Keywords: prescribing, diarrhea, WHO indicators ABSTRAK Latar Belakang: Diare merupakan masalah kesehatan dengan angka kematian yang tinggi. Tatalaksana yang tidak tepat dan cepat merupakan penyebab utama kematian akibat diare. Salah satu pencegahannya adalah dengan penggunaan obat rasional, yang dapat dinilai menggunakan indikator peresepan WHO. Tujuan: Mengetahui gambaran peresepan obat pasien diare di Puskesmas Jambi Kecil tahun 2020. Metode: Penelitian deskriptif kuantitatif dengan sampel 115 resep (total sampling) pasien diare di Puskesmas Jambi Kecil tahun 2020. Hasil: Distribusi pasien diare terbanyak adalah perempuan (56,5%), kelompok usia terbanyak 0-4 tahun (34,8%), obat diare terbanyak diresepkan adalah cairan rehidrasi oral (15,2%), rerata jumlah item obat per lembar resep 3,37 item, peresepan obat generik 94,1%, peresepan antibiotik 42,6%, peresepan injeksi 0%, dan peresepan dari DOEN 76,8%. Kesimpulan: Cairan rehidrasi oral merupakan obat yang paling banyak diresepkan, persentase peresepan obat generik dan injeksi sesuai indikator WHO, sedangkan rata-rata jumlah item obat per lembar resep, persentase antibiotik, dan peresepan dari DOEN tidak sesuai standar indikator WHO. Kata kunci : peresepan, diare, indikator WHO
Efek Melaleuca Cajuputi terhadap Gambaran Histopatologi Organ Paru Tikus yang Diinduksi Asap Rokok Cantika Dwi; Hasna Dewi; Ahmad Syauqy; Fairuz; Rina Nofrienis
Jurnal Pendidikan, Sains, Geologi, dan Geofisika (GeoScienceEd Journal) Vol. 7 No. 3 (2026): August (Inpres)
Publisher : Mataram University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/goescienceed.v7i3.2946

Abstract

Exposure to cigarette smoke can cause lung tissue damage through mechanisms of chronic inflammation and oxidative stress. Melaleuca cajuputi essential oil contains 1,8-cineole and flavonoids, which possess anti-inflammatory and antioxidant properties, thereby offering potential protective effects on lung tissue. This study aimed to analyze the effects of Melaleuca cajuputi essential oil on the histopathological features of the lungs in cigarette smoke-induced rats. This experimental study used 28 male Wistar rats divided into four groups: negative control, positive control (cigarette smoke exposure), treatment group 1 (cigarette smoke exposure + Melaleuca cajuputi aromatherapy at a dose of 0.5 mL), and treatment group 2 (cigarette smoke exposure + aromatherapy at a dose of 1 mL). The treatments were administered for 30 days, with exposure to two cigarettes per day and aromatherapy for 15 minutes daily. Histopathological parameters assessed included inflammatory cell infiltration and alveolar septal destruction. Data were analyzed using the Kruskal–Wallis test and Mann–Whitney test. The results showed that administration of Melaleuca cajuputi at a dose of 0.5 mL significantly reduced inflammatory cell infiltration scores and alveolar septal destruction compared to the positive control group. Administration of the 1 mL dose significantly reduced inflammatory cell infiltration; however, it did not show a significant difference in alveolar septal destruction compared to the positive control group.