Yana Supriatna
Department Of Radiology, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia

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Prevention, Identification, and Management of Stunting through Health Education and Entrepreneurial Capacity Building in Argomulyo Village, Sleman, Yogyakarta Torana Kurniawan; Yana Supriatna; Sri Dwidanarti; Lina Choridah; Anita Ekowati; Wigati Dhamiyati; Bambang Supriyadi; Mohammad Rizki Pratama; Abdi Alhaq
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 9, No 3 (2023): September
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpkm.83779

Abstract

Stunting is one of the world’s most serious public health issues, with significant morbidity rates, especially in Indonesia. Low public awareness of stunting and low family income are two major causes discovered especially in Special District of Yogyakarta. This community service project was undertaken to address this issue. Following the completion of the situation analysis and problem identification, a community-based problem-solving strategy in the form of health and entrepreneurship education was developed. Three medical experts provided prenatal health education to pregnant women, followed by an ultrasound screening to detect any early anomalies related to stunting. For other members of the community, experienced entrepreneurs give entrepreneurial education, which was supported by workshops for them to immediately practice the material that had been presented. It was intended that the community’s excitement would raise health awareness about stunting and the level of the local economy, allowing the stunting problem in this region to be ameliorated. It was found that the provision of health education programs had succeeded in increasing the level of community knowledge regarding stunting. Ultrasound examination found that all pregnant women in the area had normal pregnancies and fetal conditions. Community-based interventions through health education and increasing economic welfare based on tourism villages can be used to prevent stunting.
Delayed percentage attenuation ratio (DPAR) on multiphase CT as a quantitative predictor of early response in hepatocellular carcinoma Yana Supriatna; Rifki Bachtiar; Muhammad Y. Makkaraeng; Arif Budiman
Narra J Vol. 6 No. 1 (2026): April 2026
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v6i1.2996

Abstract

Hepatocellular carcinoma (HCC) remains a major cause of cancer-related mortality, and transarterial chemoembolization (TACE) is the standard therapy for intermediate-stage disease. However, response to TACE is variable, and reliable quantitative imaging biomarkers are needed to support early treatment decision-making. This study aimed to evaluate the predictive value of the delayed percentage attenuation ratio (DPAR) measured from pre-TACE multiphasic computed tomography (CT) in forecasting early therapeutic response. A retrospective cross-sectional study was conducted involving patients with a definitive diagnosis of HCC who underwent their first TACE session and had complete multiphasic CT imaging before and after treatment. Quantitative washout parameters, delayed percentage attenuation ratio (DPAR), absolute washout (WOAbs), and relative washout (WORel) were measured using standardized region of interest (ROI) placement by three radiologists. Treatment response was assessed four to six weeks post-TACE based on modified Response Evaluation Criteria in Solid Tumors (mRECIST) criteria and classified into responders and non-responders. Diagnostic performance was evaluated using receiver operating characteristic (ROC) analysis, and interobserver reliability was assessed using intraclass correlation coefficient (ICC) and Cohen’s κ. A total of 49 HCC patients were included and analyzed. Responders demonstrated significantly higher DPAR values compared with non-responders (median 134.5 vs 113.0; p<0.001). DPAR showed the strongest discriminative performance with an area under the curve (AUC) of 0.898, outperforming WOAbs (AUC 0.689) and WORel (AUC 0.704). The optimal DPAR threshold of ≥120.5 provided 84.4% sensitivity and 88.2% specificity to predict early post-TACE treatment response. Interobserver reliability was excellent for all washout parameters (ICC 0.98–0.99), and agreement for mRECIST classification was also excellent (κ=0.867). In conclusion, pre-TACE DPAR is a robust and reproducible quantitative imaging biomarker that accurately predicts early response to TACE in HCC. A threshold value of ≥120.5 may assist in treatment planning and patient selection in routine clinical practice.