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All Journal JUKESHUM: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Sciences. Grimsa Journal of Science Engineering and Technology
Mahmudi Mahmudi
Department Of Pharmacy, STIKES Assyifa Aceh, Aceh, Indonesia 23242
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Formulasi dan uji sifat fisik lulur krim ekstrak etanol bunga kecombrang (Etlingera eliator (Jack) R.M. Smith) Rina Kurniaty; Asri Ainun; Mutia Farida; Saiful Azhari; Salman Salman; Mahmudi Mahmudi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.223

Abstract

Kecombrang plant (Etlingera eliator (Jack) R.M. Smith), has bioactive compounds of polyphenols, alkaloids, flavonoids, steroids, saponins and essential oils. The purpose of this study, to make a cream scrub formulation from ethanol extract of kecombrang flowers that meets the standards and benefits on the skin. The method of this study, by varying the concentration of ethanol extract of kecombrang flowers 5% and 10% with modified formulations adding amylum oryzae as a scrub and without the addition of amyulum oryzae. The results of the 28-day study based on the parameters, in the organoleptical test had a stable shape, odor, and color, in the homogeneity test showed a homogeneous preparation, the pH test had a stable value of 7, the spreadability test had an average value of 5 cm, stable results in room or low temperature storage (2-8oC). Hedonic test results with parameters, aroma, texture, color, and effectiveness, namely formulation I 10% with an average scale value of 5, which means very like is a formulation with the addition of amylum oryzae as a scrub. Formulation results with the addition of amylum oryzae affect the preparation of abrasive formulations. The results of the skin effectiveness test, in the moisture test using a skin analyzer with an average value of moist volunteer skin at week 4, and the volunteer's skin color is slightly brighter. In conclusion, the cream scrub formulation has a good formulation, kecombrang flower extract has the effect of brightening the skin and moisturizing the skin.
Assessing Heavy Metal Contamination in Traditional Herbal Medicine (Jamu) by Atomic Absorption Spectrophotometry Mahmudi Mahmudi; Mutiara Annisa; Mutia Farida; Muhammad Yusuf; Saiful Azhari; Yunda Fachrunniza
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 1 (2023): October 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i1.4

Abstract

Heavy metal contamination of traditional herbal medicine (jamu) is a threat to humans, especially at levels above known threshold concentrations. Traditional herbal medicine found in Banda Aceh City – Indonesia, polluted by heavy metals cadmium (Cd), lead (Pb), and mercury (Hg) was performed. Heavy metal analysis used Flame - Atomic Absorption Spectrometry (FAAS) and Chemical Vapor Generation - Atomic Absorption Spectrometry (CVG - AAS) methods. The validation of the method was performed to obtain more accurate heavy metal analysis results for the samples. Heavy metal contamination, especially Pb metal, with concentrations of 4.32 ± 0.14 mg/Kg to 29.25 ± 0.24 mg/Kg. The Cd metal contamination was only found in herbal medicine sample E with a concentration of 0.80 ± 0.02 mg/Kg, above the threshold. The Hg metal contamination was also found with concentrations of 0.20 ± 0.01 to 2.14 ± 0.06 mg/Kg, and some were not detected. The government should be very concerned about stopping the distribution of herbal medicine that can be harmful to health and should inspect drug stores that still sell herbs that do not have established standards.
Vegetables, Heavy metals, FAAS, Kajian Cemaran Logam Berat Timbal (Pb), Kadmium (Cd), Dan Merkuri (Hg) Pada Sayuran Di Daerah Pertambangan Aceh Jaya Secara Spektrofotometri Serapan Atom. Rina Kurniaty; T.M. Dayan Adiyana; Muhammad Yusuf; Mahmudi Mahmudi
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.448

Abstract

Heavy metal contamination in vegetables poses a threat to humans, especially at predetermined thresholds. In this study, Pb, Cd, and Hg metals were analyzed using Flame - Atomic Absorption Spectrometry (F-AAS) and Vapor Generation Accesory - Atomic Absorption Spectrometry (VGA-AAS) methods at mining areas in Krueng Sabee Sub-District, Aceh Jaya District, Aceh Province. Method validation was conducted to obtain accurate heavy metal analysis results on the samples. The results showed that the highest Pb metal contamination was found in cassava leaf I sample with levels of 2.44 ± 1.33 mg/Kg and the lowest was found in spinach III sample with levels of 0.15 ± 0.07 mg/Kg. The high Pb content was also found in kale I and spinach I samples obtained in areas close to the mining area with levels of 1.07 ± 0.59 mg/Kg and 0.93 ± 0.50 mg/Kg, respectively. The highest Cd metal contamination content was found in kale II samples with levels of 0.11 ± 0.01 mg/Kg and the lowest Cd metal contamination with levels of 0.02 ± 0.01 mg/Kg was found in cassava leaf II samples. The highest Hg metal content of 0.58 ± 0.12 mg/Kg was found in cassava leaf I sample and the lowest level was 0.04 ± 0.02 mg/Kg owned by spinach III sample. Contamination of Hg metal in all vegetable samples showed levels that were above the established SNI 7387 (2009) quality standard of 0.03 mg/Kg. The quality standards for Pb and Cd metal contamination are 0.5 mg/Kg and 0.2 mg/Kg, respectively.  This study shows the need for government monitoring of heavy metal contamination in agricultural areas near mining activities to ensure safe food consumption.
Skrining fitokimia dan aktivitas antioksidan ekstrak etanol daging buah pala (Myristica fragrans) kawasan Aceh Selatan, Indonesia. Saiful Azhari; Rina Kurniaty; Muhammad Yusuf; Riza Zulyani; Mahmudi Mahmudi; Wahyu Mustika Rani; Mutia Farida
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.421

Abstract

The nutmeg fruit (Myristica fragrans) shows the presence of secondary metabolite compounds and has antioxidant activity. The nutmeg examined in this study is the flesh of the fruit and dried for seven days to obtain simplisia. The extraction process is by maceration method using 96% ethanol solvent. Based on the results of phytochemical screening of ethanol extracts of nutmeg flesh showed the presence of secondary metabolite compounds, which are groups of alkaloids, steroids, saponins and flavonoids. The results of antioxidant activity of ethanol extract of nutmeg flesh have an IC50 value of 22.88 ppm. In this study using vitamin C as a positive control for comparison with the IC50 value obtained is 3.82 ppm. The more secondary metabolite compounds in an extract, the higher the antioxidant activity.
Pembudidayaan Ayam Arab Petelur Untuk Meningkatkan Perekonomian Masyarakat Desa Gampong Siem Kecamatan Darussalam Kabupaten Aceh Besar Mahmudi Mahmudi; Mutia Farida; Saiful Azhari; Rina Kurniaty
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 3 No. 2 (2023): Edisi Juli 2023
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v3i2.760

Abstract

Pemberdayaan Berbasis Masyarakat (PBM) ini bertujuan untk membentuk dan mengembangkan usaha budidaya ayam arab petelur ramah lingkungan untuk miningkatkan perekonomian masyarakat Calon Pengusaha di Desa Gampong Siem Kecamatan Darussalam Kabupaten Aceh Besar. Target luaran program adalah terbentuknya kandang ayam arab petelur ramah lingkungan yang memproduksi telur, sekaligus ayam afkir, kompos, dan pengelolaan produksi dan manajemen usaha. Metode yang diterapkan untuk mewujudkan tujuan dan target luaran program adalah edukasi dan transfer Iptek dari Tim Pengabdian STIKes Assyifa Aceh kepada masyarakat Kelompok Calon Pengusaha. Implementasi program dilaksanakan selama 6 bulan. Kegiatan diawali dengan koordinasi program, presentasi dan penjelasan potensi dan peluang usaha berternak ayam arab petelur, pemeliharaan yang optimal, pengelolaan produksi dan manajemen usaha dan diakhiri dengan seminar hasil kegiatan dan publikasi. PBM bertenak ayam arab petelur telah dilaksanakan dan berhasil baik di desa Siem kecamatan Darussalam Kabupaten Aceh Besar. Mitra telah menjalankan dengan sangat baik seluruh rangkaian kegiatan PBM. Luaran program berupa kandang ramah lingkungan telah berhasil, namun luaran berupa telur belum berhasil karena perkiraan ayam arab bertelur pada Februari 2024.
Pelatihan Pembuatan Minuman Herbal Di Gampong Meunasah Mesjid Lamlhom, Lhoknga, Aceh Besar Mutia Farida; Mahmudi Mahmudi; Saiful Azhari
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2024): Edisi Januari 2024
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v4i1.834

Abstract

Kegiatan pengabdian kepada masyarakat dilakukan di Gampong Meunasah Mesjid Lamlhom, kecamatan Lhoknga Aceh Besar bertujuan untuk meningkatkan pengetahuan masyarakat untuk memvariasikan pemanfaatan bahan alam yang tersedia disekitar salah satunya bisa dijadikan minuman sehat dan dapat dipasarkan. Pengolahan bahan tersebut menjadi minuman kesehatan berbentuk minuman herbal kunyit asam dan sereh jahe adalah salah satu upaya pemanfaatan pangan yang dipandang sangat tepat dalam bidang kesehatan dan bisa menjadi salah satu sumber penghasilan tambahan jika dipasarkan dan dikemas dengan menarik. Pelaksanaan kegiatan pengabdian kepada masyarakat dilakukan dengan metode Ceramah/Sosialisasi/Sharing dan Demonstrasi. Sasaran dalam kegiatan ini adalah masyarakat Gamponng Meunasah Mesjid Lamlhom kecamatan Lhoknga Aceh Besar. Kegiatan ini dilakukan pada tanggal 26 Agustus 2023 secara tatap muka dan di laksanakan di Aula Gampong Meunasah Mesjid Lhamlhom, Lhoknga Aceh Besar. Kegiatan ini dihadiri oleh Ibu-Ibu masyarakat desa Gampong Meunasah Mesjid dan mahasiswa STIKes Assyifa Aceh.
Skrining Fitokimia dan Uji Aktivitas Antioksidan Ekstrak Etanol Daun Ciplukan (Physalis angulata L) Dikawasan Manifestasi Geothermal Seulawah Agam Mutia Farida; Saiful Azhari; Dimas Dwi Darsa; Mahmudi Mahmudi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.826

Abstract

Ciplukan leaves (Physalis angulata L.) from the Seulawah Agam geothermal manifestation area exhibit strong potential as a natural antioxidant source. This study investigates the phytochemical content and antioxidant activity of ethanol extract from ciplukan leaves using UV-Vis spectrophotometry. The research begins with sample collection and plant determination, followed by phytochemical screening and antioxidant activity testing using the DPPH method. Phytochemical screening results reveal the presence of alkaloids, flavonoids, tannins, saponins, and steroids. Antioxidant activity testing using the DPPH method yields an IC50 value of 14.99 μg/mL, significantly lower than the positive control, ascorbic acid (19.40 μg/mL), indicating strong antioxidant activity. At the highest tested concentration (50 μg/mL), the extract exhibits an inhibition percentage of 81.84%, while at the lowest concentration (10 μg/mL), it shows an inhibition of 41.41%. These findings confirm that the ethanol extract of ciplukan leaves from the geothermal area possesses high antioxidant content and has great potential for applications in the development of natural-based pharmaceutical and nutraceutical products.
Co-Authors Asri Ainun Dimas Dwi Darsa Muhammad Yusuf Muhammad Yusuf Muhammad Yusuf Mutia Farida Mutia Farida Mutia Farida Mutia Farida Mutia Farida Mutiara Annisa Rina Kurniaty Riza Zulyani Saiful Azhari Saiful Azhari Salman Salman T.M. Dayan Adiyana Wahyu Mustika Rani Yunda Fachrunniza