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All Journal JUKESHUM: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Sciences. Grimsa Journal of Science Engineering and Technology
Mahmudi Mahmudi
Department Of Pharmacy, STIKES Assyifa Aceh, Aceh, Indonesia 23242
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Formulasi dan uji sifat fisik lulur krim ekstrak etanol bunga kecombrang (Etlingera eliator (Jack) R.M. Smith) Rina Kurniaty; Asri Ainun; Mutia Farida; Saiful Azhari; Salman Salman; Mahmudi Mahmudi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.223

Abstract

Kecombrang plant (Etlingera eliator (Jack) R.M. Smith), has bioactive compounds of polyphenols, alkaloids, flavonoids, steroids, saponins and essential oils. The purpose of this study, to make a cream scrub formulation from ethanol extract of kecombrang flowers that meets the standards and benefits on the skin. The method of this study, by varying the concentration of ethanol extract of kecombrang flowers 5% and 10% with modified formulations adding amylum oryzae as a scrub and without the addition of amyulum oryzae. The results of the 28-day study based on the parameters, in the organoleptical test had a stable shape, odor, and color, in the homogeneity test showed a homogeneous preparation, the pH test had a stable value of 7, the spreadability test had an average value of 5 cm, stable results in room or low temperature storage (2-8oC). Hedonic test results with parameters, aroma, texture, color, and effectiveness, namely formulation I 10% with an average scale value of 5, which means very like is a formulation with the addition of amylum oryzae as a scrub. Formulation results with the addition of amylum oryzae affect the preparation of abrasive formulations. The results of the skin effectiveness test, in the moisture test using a skin analyzer with an average value of moist volunteer skin at week 4, and the volunteer's skin color is slightly brighter. In conclusion, the cream scrub formulation has a good formulation, kecombrang flower extract has the effect of brightening the skin and moisturizing the skin.
Assessing Heavy Metal Contamination in Traditional Herbal Medicine (Jamu) by Atomic Absorption Spectrophotometry Mahmudi Mahmudi; Mutiara Annisa; Mutia Farida; Muhammad Yusuf; Saiful Azhari; Yunda Fachrunniza
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 1 (2023): October 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i1.4

Abstract

Heavy metal contamination of traditional herbal medicine (jamu) is a threat to humans, especially at levels above known threshold concentrations. Traditional herbal medicine found in Banda Aceh City – Indonesia, polluted by heavy metals cadmium (Cd), lead (Pb), and mercury (Hg) was performed. Heavy metal analysis used Flame - Atomic Absorption Spectrometry (FAAS) and Chemical Vapor Generation - Atomic Absorption Spectrometry (CVG - AAS) methods. The validation of the method was performed to obtain more accurate heavy metal analysis results for the samples. Heavy metal contamination, especially Pb metal, with concentrations of 4.32 ± 0.14 mg/Kg to 29.25 ± 0.24 mg/Kg. The Cd metal contamination was only found in herbal medicine sample E with a concentration of 0.80 ± 0.02 mg/Kg, above the threshold. The Hg metal contamination was also found with concentrations of 0.20 ± 0.01 to 2.14 ± 0.06 mg/Kg, and some were not detected. The government should be very concerned about stopping the distribution of herbal medicine that can be harmful to health and should inspect drug stores that still sell herbs that do not have established standards.
Pembudidayaan Ayam Arab Petelur Untuk Meningkatkan Perekonomian Masyarakat Desa Gampong Siem Kecamatan Darussalam Kabupaten Aceh Besar Mahmudi Mahmudi; Mutia Farida; Saiful Azhari; Rina Kurniaty
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 3 No. 2 (2023): Edisi Juli 2023
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v3i2.760

Abstract

Pemberdayaan Berbasis Masyarakat (PBM) ini bertujuan untk membentuk dan mengembangkan usaha budidaya ayam arab petelur ramah lingkungan untuk miningkatkan perekonomian masyarakat Calon Pengusaha di Desa Gampong Siem Kecamatan Darussalam Kabupaten Aceh Besar. Target luaran program adalah terbentuknya kandang ayam arab petelur ramah lingkungan yang memproduksi telur, sekaligus ayam afkir, kompos, dan pengelolaan produksi dan manajemen usaha. Metode yang diterapkan untuk mewujudkan tujuan dan target luaran program adalah edukasi dan transfer Iptek dari Tim Pengabdian STIKes Assyifa Aceh kepada masyarakat Kelompok Calon Pengusaha. Implementasi program dilaksanakan selama 6 bulan. Kegiatan diawali dengan koordinasi program, presentasi dan penjelasan potensi dan peluang usaha berternak ayam arab petelur, pemeliharaan yang optimal, pengelolaan produksi dan manajemen usaha dan diakhiri dengan seminar hasil kegiatan dan publikasi. PBM bertenak ayam arab petelur telah dilaksanakan dan berhasil baik di desa Siem kecamatan Darussalam Kabupaten Aceh Besar. Mitra telah menjalankan dengan sangat baik seluruh rangkaian kegiatan PBM. Luaran program berupa kandang ramah lingkungan telah berhasil, namun luaran berupa telur belum berhasil karena perkiraan ayam arab bertelur pada Februari 2024.
Analisis Kadar Total Fenolik Ekstrak Etanol Daun Ciplukan (Physalis angulata L.) Dengan Metode Partisi Bertingkat Di Kawasan Geothermal Dan Non-Geothermal Mahmudi Mahmudi; Saiful Azhari; Aida Apriani; Rinaldi Rinaldi; Rozatun Uliani
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 2 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i2.1262

Abstract

Ciplukan (Physalis angulata L.) is a tropical plant with numerous benefits and is cultivated as a raw material for biopharmaceuticals, so it is no longer known as a lying plant or a weed in vacant lots by the public. Ciplukan contains secondary metabolites that can be used as active ingredients in drugs with antihyperglycemic, anti-inflammatory, antidiabetic, and cytotoxic activities. Phenolic compounds are secondary metabolites found in almost all parts of the plant. Phenolic compounds also have antioxidant properties. This is because phenolic compounds can react with free radicals and eliminate their activity so that they are no longer harmful to human cells. This study aims to determine the total phenolic content in ethanol extracts of ciplukan (Physalis angulata L.) leaves in geothermal and non-geothermal areas using a multilevel partition method. The data used to obtain total phenolic content was calculated based on a calibration curve from the readings from a UV-Vis spectrophotometer. Total phenols were calculated using a linear regression equation from the gallic acid calibration curve. Data obtained from the laboratory were processed manually and analyzed descriptively in the form of tables and graphs. The results of the total phenolic content test of the ethanol extract of ciplukan leaves (Physalis angulata L.) for the ethyl acetate fraction of the geothermal area obtained a phenolic content of 150.88% and for the ethyl acetate fraction of the non-geothermal area obtained a phenolic content of 131.68%. The results of the total phenolic content test of the ethanol extract of ciplukan leaves (Physalis angulata L.) for the N-Hexane fraction of the geothermal area obtained a phenolic content of 125.72%, and the results for the N-Hexane fraction of the non-geothermal area obtained a phenolic content of 75.01%. These results indicate that the phenolic content of ethanol extracts of ground cherry (Physalis angulata L.) leaves in geothermal areas contains higher total phenol levels than those in non-geothermal areas. These results can also serve as a basis for developing standards for ciplukan extracts from geothermal sources as a source of natural antioxidants.
Co-Authors Aida Apriani Asri Ainun Muhammad Yusuf Mutia Farida Mutia Farida Mutiara Annisa Rina Kurniaty Rinaldi Rinaldi Rozatun Uliani Saiful Azhari Saiful Azhari Salman Salman Yunda Fachrunniza