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All Journal BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan Jurnal Biologi Tropis Jurnal EduHealth Journal of Pharmaceutical and Sciences. Jurnal Cendekia Mengabdi Berinovasi dan Berkarya
Dwiyarina Margarisa
Program Studi D3 Farmasi, Universitas Mangku Wiyata, Cilegon, Banten, Indonesia.
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary

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IN VITRO PHARMACOLOGICAL ACTIVITY TEST OF TELANG FLOWER KOMBUCHA AS ANTIBACTERIAL Vibrio Cholerae AND Shigella dysenteriae THROUGH FERMENTATION BIOTECHNOLOGY METHOD Ucu Wandi Somantri; M Fariz Fadillah; Firman Rezaldi; Isti Dwi Pruschia; Dwiyarina Margarisa; Maharani Maharani
BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan Vol 11, No 2 (2023): JURNAL BIOTIK
Publisher : Universitas Islam Negeri Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/biotik.v11i2.17427

Abstract

Diarrhea that occurs in the digestive tract is a big problem for human intestinal health. This can be caused by the activity of pathogenic bacteria in the form of Vibrio cholera and Shigella dysinteriae. In this study, kombucha has been shown to have pharmacological activity in vitro in inhibiting the growth of Vibrio cholera and Shigella dysinteriae bacteria at all sugar concentrations. The purpose of this study was to determine the in vitro pharmacological activity of the butterfly pea flower kombucha in inhibiting the growth of the two test bacteria consisting of a sugar concentration of 20%, 30% and 40%. The method for testing the inhibition of both bacterial growth tests is disc diffusion. One way ANOVA and post hoc analysis are one of the quantitative test methods used in this study of the average diameter of the inhibition zone of teal flower kombucha from various sugar concentrations. The results of this study have proven based on a one-way ANOVA with each P value> 0.05 and then continued through post hoc analysis concluded that the telang flower kombucha at a concentration of 40% is the best treatment in inhibiting the growth of both test bacteria where the concentration is significantly different from sugar concentration 20% and 30%.
Fermentasi kombucha bunga telang (Clitoria ternatea L) sebagai produk bioteknologi sederhana dalam memberikan reaksi farmakodinamik mencit (Mus musculus L) yang terpapar asap rokok dan morfometri ovarium Dwiyarina Margarisa; Firman Rezaldi; Isti Dwi Pruschia; Muhammad Andry; M. Fariz Fadillah; Mutia Muhardiyanti; Hendra Jaya; Leni Halimatusyadiah; Muhammad Amin Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.254

Abstract

One of the fertility indicators in women is the optimal functioning of the ovaries. Exposure to cigarette smoke affects the decline in ovarian function in quality and quantity. The main components contained in cigarette smoke include tar, nicotine, carbon monoxide, inorganic gases, heavy metals, nitrosamines, carbonyls, formaldehyde, and polynuclear aromatic hydrocarbons. The main components contained in cigarette smoke positively influence female reproductive hormone levels and even reduce fertility. One of the efforts to prevent free radicals from cigarette smoke and have the potential as a natural antioxidant is consuming butterfly pea flower kombucha. The butterfly pea flower kombucha from previous studies contains phytochemicals that can inhibit free radicals. This study aimed to study the effect of butterfly pea flower kombucha on the ovary morphometry of female mice exposed to cigarette smoke. The design of this study was Completely Randomized Design (CRD). The test animals used were female mice aged 10 to 12 weeks weighing 20 to 20 g in a total of 24 mice. The butterfly pea flower kombucha given was ten mL/L, 20 mL/L, 30 mL/L, and 40 mL/L. Cigarette smoke exposure to mice was carried out on days 1-20 as much as one stick and treated with butterfly pea flower kombucha on days 21-40. Mating of female mice was carried out on the 40th day. Observations of ovarian morphometry such as length, width, weight, and number of corpus luteum were carried out on the 18th day of gestation. ANOVA and DMRT with a confidence level of 1% is the data analysis performed. The conclusion of this study was that butterfly pea flower kombucha had a good effect on improving fertility levels, which could be observed with test parameters such as length, width, weight, and number of corpus luteum and administration of kombucha with a concentration of 40 mL/L was the best treatment.
Factors Influencing Midwife Practices in Antenatal Services in The Early Detection of High Risk Pregnancy in Serang District Dwiyarina Margarisa; Bagoes Widjanarko; Tinuk Istiarti
Jurnal Biologi Tropis Vol. 23 No. 2 (2023): April-June
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i2.5500

Abstract

In Serang regency for 2 last years occured increasing of mother dead. This case more take place at antenatal period than having birth and porturition period. Mother dead can be prevented if high risk pregnant mother detected early, on of the method by doing pregnancy checkup appropriate with 7T standart to the pregnant mother. This research has purpose to identify and analize factors that affect midwife practice in antenatal care of high risk pregnancy early detection at Serang Regency. This research is analitik description research with cross sectional approach. The research subjects were midwife that practice BPM by use sample 73 midwifes. Result of the research showed that 52.1% respondent didn’t do antenatal care on the high risk pregnancy early detection. Factors  that related to midwife practice in antenatal care were age, education, long time of work and knowledge where result of statistic experiment was gotten p value < 0,05. Suggestion for IBI is increase monitoring and educating to its members, Health Department should be more distinct give a reward and punishment to BPM practice so that rescuing mother and baby more success, and for BPM should increase knowledges.
Merancang Program Kerja KIR (Karya Ilmiah Remaja) Biologi Kepada Siswa Siswi SMAN 5 Cilegon Dalam Upaya Lomba Menulis Artikel Ilmiah Berbasis Penelitian dan Menyusun Program Kerja Pengabdian Masyarakat Secara Rutin Dalam Setiap Semester Pruschia, Isti Dwi; Margarisa, Dwiyarina; Kartika, Shinta Dewi; Saraswati, Afrini; Rezaldi, Firman; Fatchani, Sati; Widiyaningsih, Ragil
Jurnal Cendekia Mengabdi Berinovasi dan Berkarya Vol 2 No 2 (2024): Mei
Publisher : Universitas Madako Tolitoli

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56630/jenaka.v2i2.574

Abstract

SMAN 5 Cilegon merupakan salah satu daerah di Wilayah Banten  yang memiliki potensi peternakan  yang cukup besar.  Potensi investasi peternakan di wilayah ini mencakup peternakan ungags dan mammalia.   Untuk meningkatkan pemanfaatan serta daya saing produk bioteknologi farmasi  salah satu yang dapat dilakukan dengan cara mendorong pada generasi muda khususnya siswa/i SMA Negeri 5 Cilegon untuk melakukan kegiatan penulisan artikel ilmiah berbasis penelitian bagi siswa/i yang terlibat dalam KIR biologi.  Kegiatan  ini dilaksanakan pada sabtu tanggal 20 Januari 2024.  Bertempat di SMA Negeri 5 Cilegon, Provinsi Banten.  Prosedur  pelaksanaan kegiatan ini yaitu pertemuan langsung untuk penyampaian materi oleh narasumber kepada siswa/i  di SMA Negeri 5 Cilegon. Hasil Perwakilan Dosen yang menyampaikan telah terbukti  secara keseluruhan siswa/i telah memahami potensi kombucha bunga telang sebagai antibiotik natural yang ramah lingkungan dan dapat dimanfaatkan sebagai bahan aktif obat maupun kosmetik dan di harapkan setelah kegiatan yaitu daya minat untuk melanjutkan studi lebih meningkat kembali pada perguruan tinggi yang ditargetkannya.Kata kunci : KIR, Biologi, Artikel Ilmiah, Penelitian 
Patterns Of Medication Prescribing In Adolescent Patients With Mental Disorders At Krakatau Medika Hospital City Of Cilegon For The Period Of January–December 2023 Isti Dwi Pruschia; Maharani, Maharani; Dwiyarina Margarisa; Shinta Dewi Kartika; Dwi Astriani
Jurnal EduHealth Vol. 15 No. 04 (2024): Jurnal EduHealt (inpres), Year 2024
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mental Disorders or Mental Illness is a disease that affects the sufferer's emotions, thought patterns and behavior, a term that refers to various conditions that affect feelings and mood. This study aims to determine the pattern of drug prescribing in adolescent patients with mental disorders at Krakatau Medika Hospital, Cilegon City for the period January - December 2023. This research is a descriptive study with retrospective data collection using patient medical record data. The sampling technique used in this research was Total Sampling using 61 samples. The variables used in this research are drug prescribing patterns, mental disorders, age and gender. The research results showed that the percentage of use of the Antidepressant drug class in the pattern of drug prescribing was higher than other psychopharmacological drug classes, patients received several types of drugs which were included in the Antidepressant drug group and there were combinations of drugs other than the Psychopharmaca drug class. Based on mental disorders, patients with depression are higher than other mental disorders, namely (44.30%). In the classification of adolescents aged 18 – 24 years, the highest percentage was at the age of 21 years, namely (23.00%) and gender, women experienced more mental disorders, namely 57.30%.
Co-Authors Bagoes Widjanarko Dwi Astriani Fatchani, Sati Firman Rezaldi Firman Rezaldi Hendra Jaya Isti Dwi Pruschia Kartika, Shinta Dewi Leni Halimatusyadiah M Fariz Fadillah M. Fariz Fadillah Maharani Maharani Maharani Maharani, Maharani Muhammad Amin Nasution Muhammad Andry Mutia Muhardiyanti Rezaldi, Firman Saraswati, Afrini Shinta Dewi Kartika Tinuk Istiarti Ucu Wandi Somantri Widiyaningsih, Ragil