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All Journal BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan Journal of Agromedicine and Medical Sciences Jurnal Biologi Tropis Jurnal Biotek Jurnal Dunia Farmasi Indonesian Journal of Global Health research Jurnal Gizi Kerja dan Produktivitas Jurnal Ilmiah Agribios FORTE JOURNAL Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Journal of Health and Medical Science Jurnal Farmasi Sains dan Praktis Prosiding Seminar Nasional Rekayasa Teknologi Industri dan Informasi ReTII Gunung Djati Conference Series Journal of Applied Plant Technology Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat Ilmu Kesehatan Media Penelitian dan Pengembangan Kesehatan

Muhammad Andry

Program Studi Farmasi, Fakultas Farmasi Dan Kesehatan, Institut Kesehatan Helvetia, Medan, Sumatera Utara, Indonesia.

Author-ID : 6323708

Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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ANTIFUNGAL Trycophyton rubrum AND Trycophyton mentagrophytes IN LIQUID BATH SOAP FERMENTED PROBIOTIC KOMBUCHA FLOWER TELANG (Clitoria ternatea L) AS A PHARMACEUTICAL BIOTECHNOLOGY PRODUCT Barolym Tri Pamungkas; Ayu Safitri; Firman Rezaldi; Muhammad Andry; Lucky Dita Agustiansyah; M. Fariz Fadillah; Fajar Hidayanto; Hari Hariadi
BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan Vol 10, No 2 (2022): JURNAL BIOTIK
Publisher : Universitas Islam Negeri Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/biotik.v10i2.15160

Telang flower kombucha (Clitoria ternatea L) is a functional probiotic drink that has antifungal properties. This study aimed to examine the antifungal activity of the probiotic bath soap formulation fermented kombucha telang flower against Trycophyton rubrum and Trycophyton mentagrophytes. This research method was carried out experimentally in an in vitro laboratory. The formulation of the fermented kombucha bath soap for the flower of telang was made with varying concentrations of 20%, 30%, and 40%. The preparation of probiotic bath soap for kombucha telang flower was tested for its antifungal activity against the bacteria T. rubrum and T. megantrophytes using the disc diffusion method. The working procedure includes the manufacture of bath soap preparations, and antifungal activity tests on the probiotic kombucha bath soap preparations of telang flower. The results of the study were positively correlated based on the one-way ANOVA test with f count greater than f table and showed that telang flower kombucha in the form of probiotic bath soap had antifungal activity against T. rubrum and T. mentagrophytes as a whole. The concentration of 40% was the highest concentration in the probiotic soap preparations fermented kombucha telang flower with an average inhibition zone diameter of 17.70 mm in T. rubrum species and 17.30 mm in T. mentagrophytes species. The average value of the diameter of the inhibition zone is included in the strong category.

SIMULTANEOUS CONTENT ANALYSIS OF RIFAMPICIN, ISONIAZID, AND PYRAZINAMIDE IN TABLET DOSAGE FORM BY SPECTROPHOTOMETRY ULTRAVIOLET WITH DWM AND RSM Luthvia Luthvia; Muhammad Andry
Jurnal Farmasi Sains dan Praktis Vol 8 No 3 (September-December 2022)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v8i3.6241

Treatment of active tuberculosis requires the use of combinations of drugs. One of the common combination of drugs to serve as anti-tubercular medication is rifampin, isoniazid and pyrazinamide. However, a research conducted by the Food Drug Administration (FDA) concluded that the combination of anti-tubercular medication may pose some patients to the risk of sub-optimal drug exposure, which may lead to less optimal treatment. This study aimed to determine the drug level of combination of anti-tubercular medication, namely rifampin, isomiazid, and pyrazinamide and to develop a spectrophotometric method using the dual wavelength method (DWM) and ratio substaction method (RSM) in tablet preparations on the market without separation. During the preparation, methanol was used as the solvent, followed by dilution, determination of calibration curve, determination of wavelength (λ), measurement, data analysis and validity test with several parameters ranging from linearity, accuracy, precision, LOD, and LOQ. The research revealed that the drug levels of rifampin, isoniazid, and pyrazinamide from the ultraviolet spectrophotometric method using sequential DWM were 100.3±1.8785; 99.98±2.5943; 100.03±2.076 and the results of the ultraviolet spectrophotometric method using RSM sequentially were 99.73±0.5437; 99.84±1.7598; 99.91±1.4762. Both methods succeeded in determining the drug level of the combination of rifampin, isoniazid, and pyrazinamide in tablet preparations without separation and the results of the validation parameters met the requirements.

Anti-Inflammatory Activity of Stem Barks Ethanol Extracts of Asam Kandis On Male White Rats Hanafis Sastra Winata; Muhammad Andry; Muhammad Amin Nasution; Firman Rezaldi; Ade Shindy F Br Sembiring
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.37478

Inflammation is a complex series of changes in tissue due to tissue injury caused by bacteria, trauma, chemicals, heat, and pain. Gamboge (Garcinia xanthochymus) is a fruit-bearing tree native to Southeast Asia. Plants of the genus garcinia are rich in secondary metabolites such as flavonoids, steroids, and triterpenes which have potential pharmacological activity. This study aimed to determine the anti-inflammatory activity based on the reduction in edema volume of Gamboge (Garcinia xanthochymus) stem bark. The inquiry was experimental. Through maceration, an ethanol extract of the gamboge stem was created. The animals were divided into five groups, each containing five white male rats. The test given was a suspension of gamboge ethanol extract at doses of 200, 400, and 600 mg/kgBW, a negative control of 1% Na CMC suspension, and a positive control of 2.25 mg/kgBW sodium diclofenac. Observations were made for 6 hours, and then data were analyzed using a two-way analysis of variance (ANOVA) test. The results showed that gamboge ethanolic extract was proven to have an anti-inflammatory effect in white male rats induced by carrageenan starting at doses of 200, 400, and 600 mg/kgBW, marked by a significant difference to the negative control (p<0.05). The 600mg/kgBW dose group showed no significantly different results from the positive control group (p>.05). These results concluded that the dose group 600mg/kgBW was the best dose of gamboge stem ethanol extract had an anti-inflammatory activity based on reducing the volume of leg edema of white male rats. Keywords: Asam Kandis Stem Bark; Anti-Inflammation; Male White Rats

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.37478

Uji Aktivitas Antibakteri Ekstrak Etanol Daun Sisik Naga terhadap Bakteri Staphylococcus aureus dan Salmonella typhi Muhammad Amin Nasution; Muhammad Andry; Hindri Syahputri; Nia Novranda Pertiwi; Melia Sari
Jurnal Dunia Farmasi Vol 7, No 2 (2023): Edisi April
Publisher : Program Studi Farmasi, Fakultas Farmasi dan Kesehatan, Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jdf.v7i2.5693

Latar Belakang: Paku sisik naga (Pyrrosia piloselloides) termasuk dalam family Polypodiaceae merupakan tanaman epifit yang hidup dan menempel di bebatuan atau pepohonan dan mengandung metabolit sekunder seperti alkaloid, flavonoid, saponin. Tujuan: Untuk mengetahui metabolit sekunder yang terdapat pada sampel serta menguji aktivitas antibakteri dan konsentrasi yang paling baik ekstrak etanol sisik naga (Pyrrosia piloselloides) dalam menghambat pertumbuhan bakteri Staphylococcus aureus dan Salmonella typhi. Metode: Penelitian ini eksperimental dengan ekstraksi metode maserasi dengan pelarut etanol 96%. Sampel penelitian ini adalah daun tropofil sisik naga (Pyrrosia piloselloides) diambil secara purposive sampling yang diekstrak kemudian diencerkan dengan konsentrasi 10%, 20% dan 30%. Uji daya hambat menggunakan metode difusi cakram. Data yang diperoleh dari hasil penelitian di laboratorium diolah dengan statistik yaitu uji Analysis of Varians (ANOVA). Hasil: Berdasarkan uji anova diketahui nilai sig sebesar 0,000 (0,005) terdapatl perbedaan signifikan antara konsentrasi 10%, 20%, 30%, kontrol (+) dan kontrol (-) dengan kata lain penambahan konsentrasi mempengaruhi zona hambat mikroba. Kesimpulan: Pada penelitian ini dapat disimpulkan bahwa uji aktivitas antimikroba dan konsentrasi pada ekstrak etanol sisik naga (Pyrrosia piloselloides) mempunyai aktivitas antimikroba terhadap bakteri Staphylococcus aureus dan Salmonella typhi.

Analisis Kepuasan Pasien Rawat Jalan Terhadap Kualitas Pelayanan Kefarmasian Di Puskesmas Lhoksukon Aceh Utara Tahun 2022 Mayang Sari, Rahma Wani, Muhammad Andry
Journal of Health and Medical Science Volume 2 Nomor 2 April 2023
Publisher : CV. Pusdikra Mitra Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51178/jhms.v2i2.1343

Puskesmas adalah fasilitas pelayanan kesehatan yang menyelenggarakan upaya kesehatan masyarakat tingkat pertama, dengan lebih mengutamakan upaya promotif dan preventif, untuk mencapai derajat kesehatan yang setinggi-tingginya di wilayah kerjanya. Tujuan dari penelitian ini untuk mengetahui tingkat kepuasan dan kualitas pelayanan kefarmasian di Puskesmas Lhoksukon Aceh Utara. Metode penelitian ini menggunakan metode penelitian survei deskriptif. Populasi pada penelitian ini adalah seluruh pasien rawat jalan yang mendapatkan pelayanan kefarmasian di UPTD Puskesmas Lhoksukon Aceh Utara yang memenuhi kriteria inklusi sebanyak 6.114 pasien. Jumlah sampel dalam penelitian ini menggunakan rumus Slovin sebanyak 98 orang. Analisis data yang digunakan dalam penelitian ini yaitu analisis univariat dan dideskripsikan. Hasil penelitian ini Kepuasan pasien terhadap bukti fisik (72,72%), Kepuasan pasien terhadap kehandalan (70,68%), Kepuasan pasien terhadap ketanggapan (70,88%), Kepuasan pasien terhadap jaminan (72,65%), dan Kepuasan pasien terhadap kepedulian (71,15%). Dari 5 dimensi memperoleh skor rata-rata (71,61%) yang menyatakan Indeks Kepuasan pasien di Puskesmas Lhoksukon Aceh Utara.

Growth Inhibition Test of Gram and Negative Bacteria in Pharmaceutical Biotechnology Products in the Form of Hand Sanitizer Formulations Based Fermented Telang Flower Kombucha Hari Hariadi; Muhammad Andry; Muhammad Amin Nasution; Ade Sumiardi; Firman Rezaldi; Suseno Amien; Yusep Ikrawan
Jurnal Biologi Tropis Vol. 23 No. 3 (2023): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i3.5219

Telang flower kombucha is proven to have various pharmacological activities, so that it can be developed as medicines, cosmetics, and its waste can be applied in agriculture as an ingredient in organic liquid fertilizer to support plant development and growth. This research aims to make hand sanitizer gel formulations and preparations with active butterfly pea flowers. Disk diffusion is used to stop gram-positive and gram-negative bacteria from growing. Post hoc analysis and one-way ANOVA were used to analyze the data. The one-way ANOVA analysis yielded results with a significance level of P<0.05, allowing the post hoc test to continue. When tested at a sugar concentration of 40%, the butterfly pea flower kombucha hand sanitizer significantly outperformed the control when it came to inhibiting the growth of the test bacteria. The best way to stop the test bacteria from growing is to use a concentration of 40%.

UJI AKTIVITAS KRIM ANTI JERAWAT EKSTRAK ETANOL DAUN SEROJA (Nelumbo nucifera G.) TERHADAP BAKTERI Propionibacterium acnes DAN Staphylococcus aureus Khairani Fitri; Tetty Noverita Khairani; Muhammad Andry; Nidia Rizka; Muhammad Amin Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background; Lotus leaves (Nelumbo nucifera G.) is one of the plants that are potentially in the field of treatment, like antibacterial antiacne. Lotus leaves contain alkaloids, saponins, tannins, flavonoids and steroids are compounds of secondary metabolites in plants that are effective as an antibacterial. Objective; The study aimed to determine the antibacterial activity of lotus leaves ethanol extract against bacteria of Propionibacterium acnes and Staphylococcus aureus. Method; The ethanol extract of lotus leaves was made by maceration method using 96% ethanol as a solvent. The in-vitro antibacterial activity test used the well method with a concentration of 10%, 20% and 30%. Results; The results of the study with concentration of 10%, 20% and 30% have the inhibition zone on the bacteria Propionibacterium acnes where the concentration of 10% of 8.7mm, a concentration of 20% of 12.4mm and a concentration of 30% by 14.5mm. And the zone of inhibition on Staphylococcus aureus bacteria has a 10% concentration of 8.1mm, the concentration of 20% of 11.1mm and a concentration of 30% of 14.1mm. Concentration is the cream of the ethanol extract of the leaves of lotus at a concentration of 30%. Conclusion; The conclusion of this study showed that the ethanol extract of lotus leaves could be formulated in a cream dosage form and has antibacterial activity against Propionibacterium acnes and Staphylococcus aureus bacteria. It is suggested to the next researchers to do fractionation to get better dosage results.

TINGKAT KEPUASAN PASIEN RAWAT JALAN TERHADAP PELAYANAN KEFARMASIAN DI UPTD PUSKESMAS KUTA BLANG KABUPATEN BIREUEN Fahma Shufyani; Mayang Sari; Muhammad Andry; Dwi Dominica
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background; service quality is an important factor that can shape the trust of Health center patients to create loyalty and patient satisfaction with health services. The results of observations and brief interviews conducted with 11 outpatients at the Pharmacy of UPTD Kuta Blang Health Center, Bireuen Regency, found 6 patients who complained about services in daily operations, the lack of delivery of drug information and the limitations of drugs provided at the Health Center. Objectives; this study aimed to determine the level of patient satisfaction with pharmaceutical services at UPTD Kuta Blang Health Center, Bireuen Regency. Method; this is a descriptive survey method. The population of this study was 4,061 people with samples taken by using the slovin formula as many as 98 people. Analysis of the data used descriptive analysis. Result; the results of the study on the level of patient satisfaction with pharmaceutical services at UPTD Kuta Blang Health Center showed that the highest level of satisfaction was in the responsiveness dimension of 68.6%, physical evidence 67.1%, empathy 65.2%, assurance 62.7% and the last dimension of reliability is 62.2%. Conclusion; the conclusion of the study shows that the average percentage of patient satisfaction with pharmaceutical services at UPTD Kuta Blang Health Center, Bireuen Regency as a whole is 65.6% with the classification of satisfaction being dissatisfied.

Penetapan kadar flavonoid total ekstrak etanol buah asam kandis (Garcinia xanthochymus) dengan metode spektrofotometri Uv-Vis dan LCMS Hanafis Sastra Winata; Hendri Faisal; Muhammad Andry; Nurul Aulia; Muhammad Amin Nasution; Ika Julianti Tambunan
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.159

Background: Kandis acid fruit (Garcinia xanthocymus Hook. f ex T. Anderson) is a plant of the Clusiase family with many species. Kandis acid fruit has various biological and pharmacological activities such as cytotoxic, anti-inflammatory, antimicrobial, antifungal and antioxidant. Purpose: To determine the content and total flavonoid content of tamarind kandis using quercetin as a reference standard. Method: This study used the TLC (Thin Layer Chromatography) method in qualitative analysis with the parameter Rf, then used the spectrophotometric method in the quantitative analysis with the parameter total flavonoid content (Value of mg QE/g sample) and the LCMS method (Liquid Chromatography Mass Spectrometry) with the parameter retention time (Rt). Result: Shows that tamarind kandis has an Rf value of 0.86 which states that tamarind kandis is positive for flavonoids with a reference standard of quercetin, total flavonoid content of 34.8364 mg QE/g sample with a standard deviation of 0.4355 and a percentage of 0.6967% and has five types of flavonoid compounds namely methyl dihydro quercetin, 1,5-Dihydroxy-3-methoxy xanthone, Afzelechin, Myricetin-3-O-ß-D-galactopiranoside, and Myricetin 7-glucoside. Methyl dihydro quercetin is the largest flavonoid with a composition of 49.57% with a retention time of 0.485 minutes. Conclusion: The identified total flavonoids have different types and levels

Co-Authors Abadi, Hafizhatul Abas, Mohd Ihsanuddin Bin Ade Shindy F Br Sembiring Ade Sumiardi Adek Chan Agustiansyah, Lucky Dita Aji, Andrey Akmal Muhni Anggi, Reza Destri Arfiani Arifin Aris Ma'ruf Asyrun Alkhairi Lubis Ayu Safitri Ayu Safitri Ayu Safitri Ayu Wulan Putri Selayan Bakri , Tedy Kurniawan Budiadi Diana, Vivi Eulis Dini Permata Sari Dominica, Dwi Dwiyarina Margarisa Erina Candra Wati Ervina Syahfitri Lubis Fahma Shufyani Faisal , Hendri Faisal, Hendri Fajar Fakri Fajar Hidayanto, Fajar Fira Safitri Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Firman Rezaldi Fitri, Khairani Ginting , Indra Ginting, Indra Gumilar, Roni Hafid Syahputra Hanafis Sastra Winata Hanafis Satra Winata Hari Hariadi Hari Hariadi Hari Hariadi, Hari Hartini, Putri Tri Hendra Jaya Hendri Faisal Hendri Faisal Hendri Faisal Hendri Faisal Hindri Syahputri Husaini, Fahri Husnarika Febriani, Husnarika Ika Julianti Tambunan Illian , Didi Nurhadi Indra Ginting Isnaini , Nadia Isti Dwi Pruschia Jashima Ukhtia Jefri Naldi Jefri Naldi Karo-Karo, Sry Ulina Khairani Fitri Khairani, Tetty Noverita Leni Halimatusyadiah Leni Widiarti, Leni Leny Leny, Leny Ligo, Azzura Lilik Septiana Lubis, Indah Pertiwi Lubis, Meiva Amalia Lucky Dita Agustiansyah Lucky Dita Agustiansyah Lumbantoruan, Jernih Marisatua Luthvia Luthvia Luthvia, Luthvia M. Fariz Fadillah M. Fariz Fadillah M. Fariz Fadillah M. Fariz Fadillah M. Fariz Fadillah M. Fariz Fadillah Mardianto Maritha, Vevi Marseli, Cindy Mayang Sari Melia Sari Melia Sari Melia Sari, Melia Mochammad Imron Awalludin Muhammad Amin Nasution Muhammad Amin Nasution Muhammad Amin Nasution Muhammad Fauzan Lubis Muhammad Yunus Muhammad Yunus Mukhali, Hassan Basri bin Mulidan, Mulidan Mutia Muhardiyanti Nabila, Nabila Naldi, Jefri Nasution , Muhammad Amin Nasution, Halimnah Raina Naziyah, Syifa Ngete, Ani Florida Nia Novranda Pertiwi Nidia Rizka Ningrum, Nurlian Augustin Ningtias, Anggitha Nurcahyani, Nadya Nurfitriyana Nurfitriyana Nurjanah, Ayu Nurul Aulia Pamungkas, Barolym Tri Panjaitan, Yuli Cahyani Pradita, Diding Pricella Ginting Puteri, Cut Intan Annisa Rachelli, Rachelli Rafifah Azzahra Raisa Fadila Ramadaini, Tiara Ratna Fitri Yenny, Ratna Fitri Rezaldi, Firman Rida Evalina Tarigan Rizqi Muhammad Mahbub Rudang , Singgar Ni Rudang, Singgar Ni Rumanti, Ruth Mayana Rustini Sajaratud Dur, Sajaratud Sari, Syilvi Rinda Sarumaha, Paska Eli Shaum Shiyan Shufyani, Fahma Sibero, Jitasari Tarigan Simahate, Sadjnah Simanjuntak, Monica Nelly Siska Dwi Anggraeni Situmorang, Renni Paska Surbakti, Chemayanti Suseno Amien Susiyanti Susiyanti Syariful Mubarok Tetty Noverita Khairani Tetty Noverita Khairani Tetty Noverita Khairani Tri Mayanti Ulfa Melyza Utama, Rezza Fikrih Vannissa Andriani Irawan Vevi Maritha Wijayanti, Fitria Eka Resti Winata, Hanafis Sastra Yudianto, Tri Yusep Ikrawan Ziza Putri Aisyia Fauzi

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