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Leni Halimatusyadiah
Sekolah Tinggi Ilmu Kesehatan Salsabila Serang
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Pelatihan Pembuatan Jamu Instan Pada Masyarakat Di Desa Kemanisan Kecamatan Curug Serang Sebagai Upaya Peningkatan Kemandirian Ekonomi Keluarga Yusransyah Yusransyah; Sofi Nurmay Stiani; Fathiyati Fathiyati; Sandy Nurlaela Rachman; Leni Halimatusyadiah; Endah Endah; Renditya Ismiyati; Andri Harpan; Meila Pertiwi
Jurnal Abdi Masyarakat Kita Vol 3 No 1 (2023): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/asta.v3i1.366

Abstract

Traditional medicines are ingredients in the form of plant ingredients, animal ingredients, mineral ingredients, galenic preparations, or mixtures of these materials which have been used for generations for treatment and can be applied in accordance with the norms in force in society, while herbal medicine is a Traditional Medicine made in Indonesia. The purpose of this research is to increase understanding of the importance of increasing understanding regarding the processing of instant herbal medicine and raising awareness of the importance of improving skills in the form of training on making good and correct instant herbal medicine in Kemanisan village. The community service method used in this research is in the form of community relations through counseling and health training. The results showed that the knowledge level of the respondents before the training, namely 41,7 %, was in the sufficient category. The respondents' knowledge level after the training was 50% in the good category. Based on the study results, it can be concluded that the respondents' knowledge level before and after counseling and training increased their knowledge. Community service activities through counseling methods can increase respondents' knowledge regarding managing medicinal plants into an instant herbal products with economic value.
Edukasi Penggunaan Obat pada Bulan Ramadhan Ditinjau dari Segi Kesehatan dan Islam Di SMK Babunajah Pandeglang Sofi Nurmay Stiani; Yusransyah Yusransyah; Sylvi Addini; Leni Halimatusyadiah; Fathiyati Fathiyati; Syifa Maulidia Rizqi; Dewi Intan Sri Rahayu; Hanifah Dwi Safitri
Jurnal Pengabdian Pada Masyarakat Vol 8 No 3 (2023): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v8i3.486

Abstract

Bulan Ramadhan merupakan waktu bagi umat muslim dalam melaksanakan kewajiban untuk berpuasa. Bagi yang melaksanakan puasa dan mengalami gangguan kesehatan, pasti akan mempengaruhi konsumsi atau pola penggunaan obat seperti pada hari-hari biasa. Perubahan jadwal penggunaan obat sangat perlu diperhatikan sehingga tidak mempengaruhi efek terapi yang diberikan atau yang sedang dijalani. Tujuan penelitian ini dilakukan untuk memberikan edukasi kepada masyarakat supaya tetap dapat mengkonsumsi obat dengan benar tanpa meninggalkan ibadah puasanya. Metode pengabdian masyarakat yang digunakan dalam penelitian ini yaitu community relation melalui edukasi mengenai pengetahuan penggunaan obat saat puasa kepada peserta. Hasil penelitian menunjukkan bahwa tingkat pengetahuan responden sebelum diberikan edukasi yaitu 56% berada pada kategori cukup. Tingkat pengetahuan responden setelah diberikan edukasi yaitu 90% pada kategori baik. Berdasarkan hasil penelitian dapat disimpulkan bahwa tingkat pengetahuan responden sebelum dan sesudah diberikan edukasi mengalami peningkatan pengetahuan secara signifikan dengan nilai p<0,05. Kegiatan pengabdian kepada masyarakat melalui pemberian edukasi dapat meningkatkan pengetahuan responden tentang penggunaan obat yang baik dan benar saat puasa. The month of Ramadan is the time for Muslims to carry out the obligation to fast. For those who carry out fasting and experience health problems, it will definitely affect consumption or patterns of drug use as on normal days. Changes in the schedule for drug use really need to be considered so that it does not affect the effect of the therapy being given or being carried out. The purpose of this research was provided education to the public so that they can continue to take medication properly without leaving their fasting worship. The community service method used in this study was community relations through education about the knowledge of using drugs during fasting to participants. The results showed that the level of knowledge of the respondents before being given education, namely 56%, was in the sufficient category. The level of knowledge of respondents after being given education was 90% in the good category. Based on the results of the study it can be concluded that the level of knowledge of respondents before and after being given education experienced a significant increase in knowledge with a p value <0.05. Community service activities through the provision of education can increase respondents' knowledge about the proper and correct use of drugs during fasting.
Fermentasi kombucha bunga telang (Clitoria ternatea L) sebagai produk bioteknologi sederhana dalam memberikan reaksi farmakodinamik mencit (Mus musculus L) yang terpapar asap rokok dan morfometri ovarium Dwiyarina Margarisa; Firman Rezaldi; Isti Dwi Pruschia; Muhammad Andry; M. Fariz Fadillah; Mutia Muhardiyanti; Hendra Jaya; Leni Halimatusyadiah; Muhammad Amin Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.254

Abstract

One of the fertility indicators in women is the optimal functioning of the ovaries. Exposure to cigarette smoke affects the decline in ovarian function in quality and quantity. The main components contained in cigarette smoke include tar, nicotine, carbon monoxide, inorganic gases, heavy metals, nitrosamines, carbonyls, formaldehyde, and polynuclear aromatic hydrocarbons. The main components contained in cigarette smoke positively influence female reproductive hormone levels and even reduce fertility. One of the efforts to prevent free radicals from cigarette smoke and have the potential as a natural antioxidant is consuming butterfly pea flower kombucha. The butterfly pea flower kombucha from previous studies contains phytochemicals that can inhibit free radicals. This study aimed to study the effect of butterfly pea flower kombucha on the ovary morphometry of female mice exposed to cigarette smoke. The design of this study was Completely Randomized Design (CRD). The test animals used were female mice aged 10 to 12 weeks weighing 20 to 20 g in a total of 24 mice. The butterfly pea flower kombucha given was ten mL/L, 20 mL/L, 30 mL/L, and 40 mL/L. Cigarette smoke exposure to mice was carried out on days 1-20 as much as one stick and treated with butterfly pea flower kombucha on days 21-40. Mating of female mice was carried out on the 40th day. Observations of ovarian morphometry such as length, width, weight, and number of corpus luteum were carried out on the 18th day of gestation. ANOVA and DMRT with a confidence level of 1% is the data analysis performed. The conclusion of this study was that butterfly pea flower kombucha had a good effect on improving fertility levels, which could be observed with test parameters such as length, width, weight, and number of corpus luteum and administration of kombucha with a concentration of 40 mL/L was the best treatment.
UJI DAYA HAMBAT BAKTERI Staphylococcus epidermidis, Vibrio parahaemolyticus, Escherichia coli DARI PRODUK BIOTEKNOLOGI FARMASI BERUPA SABUN CUCI TANGAN KOMBUCHA BUNGA TELANG (Clitoria ternatea L) Leni Halimatusyadiah; Rina Octavia; Endang Safitri; Firman Rezaldi; M. Fariz Fadillah; Desi Trisnawati
Jurnal Kesehatan dan Kedokteran Vol. 1 No. 3 (2022): Oktober: Jurnal Kesehatan dan Kedokteran
Publisher : Asosiasi Dosen Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56127/jukeke.v1i3.381

Abstract

Kombucha bunga telang selain berpotensi sebagai minuman probiotik dalam meningkatkan sistem kekebalan tubuh memiliki potensi juga sebagai bahan aktif sabun cuci tangan dalam menghambat pertumbuhan bakteri Staphylococcus epidermidis, Vibrio parahaemolyticus, dan Escherichia coli. Tujuan penelitian ini adalah untuk membuat formulasi dan sediaan sabun cuci tangan yang berbahan aktif larutan fermentasi kombucha bunga telang dengan konsentrasi gula 20%, 30%, dan 40%. Metode penelitian ini dilakukan secara eksperimental laboratorium dengan membuat 4 sediaan sabun cuci tangan dan menyediakan sabun cuci tangan pasaran untuk diuji pada ketiga pertumbuhan bakteri uji melalui metode difusi cakram. Analisis data yang digunakan adalah ANOVA satu jalur dilanjut melalui Analisis pos hoc. Hasil penelitian ini disimpulkan bahwa sabun cuci tangan yang berbahan aktif larutan fermentasi kombucha bunga telang berkolerasi secara positif dalam menghambat ketiga pertumbuhan bakteri uji. Konsentrasi 40% pada sediaan sabun cuci tangan kombucha bunga telang berbeda nyata secara signifikan dengan nilai F tabel lebih kecil dibanding F hitung (P<0,05) pada konsentrasi 20%, 30%, dan basis sabun. Namun tidak berbeda nyata dengan sabun cuci tangan yang tersedia dipasaran dalam menghambat ketiga pertumbuhan bakteri uji. Konsentrasi 40% (sabun cuci tangan kombucha bunga telang) konsentrasi terbaik dari seluruh perlakuan dalam menghambat ketiga pertumbuhan bakteri uji.
Comparison of the Toxicity of Watermelon Rind Extract (Citrullus lanatus) and Melon Rind Extract Using BSLT Method Fajrin Noviyanto Fajrin; Rinditya Lutfiah Syafa Kurnadi; Eva Kholifah; Afifah Nur Shobah; Leni Halimatusyadiah
Jurnal Ilmiah Sains Volume 24 Issue 1, April 2024
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v24i1.49263

Abstract

Toxicity analysis is a preliminary test to observe a toxic pharmacological activity to find a safe dose to be developed into a new drug. The plants that potentially have poisonous effects are Watermelon rind (Citrullus lanatus) and Melon rind (Cucumis melo). The purpose of this study was determine the toxic potential of watermelon rind and melon rind using Brine Shrimp Lethality Test. Test BSLT and phytochemical screening. The results of research on watermelon rind and melon rind contain secondary metabolites, amely alkaloids, flavonoids, tannins, saponins. The result of the BSLT test watermelon rind extract and melon rind extract were different. For watermelon rind extract, the LC50 value was 305,19 µg/ml and for melon rind extract, the LC50 value was 816,73 µg/ml. The LC50 value pbtained from the research results of the two samplees is toxic to Artemia salina Leach, because the LC50 value is < 1000 µg/ml. Statistical test results using One Way Anova obtained a significant value of 0.027 where there were significant differences in the two samplesand various concertration, but both plants had the same toxic effect on Artemia salina Leach larvae. Keywords: Citrullus lanatus; Cucumis melo; LC50; toxicity
Aplikasi Metode Bioteknologi Fermentasi Kombucha Buah Nanas Madu (Ananas comosus) Subang Sebagai Antibakteri Gram Positif Dan Negatif Berdasarkan Konsentrasi Gula Yang Berbeda Rezaldi, Firman; Fadillah, M. Fariz; Agustiansyah, Lucky Dita; Tanjung, Siti Aisiyah; Halimatusyadiah, Leni; Safitri, Endang
Jurnal Agroteknologi Merdeka Pasuruan Vol 6, No 1 (2022): JUNI 2022
Publisher : Universitas Merdeka Pasuruan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51213/jamp.v6i1.70

Abstract

Tujuan dari penelitian ini adalah untuk menghasilkan rata-rata diameter zona hambat pada bakteri keempat bakteri uji yang difermentasi oleh kombucha buah nanas madu Subang berdasarkan konsentrasi gula pasir putih yang berbeda-beda. Konsentrasi gula pasir putih yang digunakan dalam penelitian ini adalah 15%, 25%, dan 35%. Tahapan sebelum dilakukan aktivitas antibakteri gram positif dan negatif yaitu dengan cara mengidentifikasi kandungan metabolit sekunder pada ampas kulit buah nanas sebagai skrining awal dalam pembuatan kombucha buah nanas. Hasil skrining fitokimia pada ampas kulit buah nanas madu Subang mengandung alkaloid, flavonoid, saponin, dan tanin. Hasil fermentasi kombucha buah nanas madu Subang berpotensi sebagai antibakteri pada bakteri Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, dan Escherichia coli. Kombucha buah nanas madu Subang dapat dikategorikan sebagai antibakteri dalam spektrum luas yang telah terbukti berpotensi dalam menghambat pertumbuhan bakteri patogen. Konsentrasi gula 40% merupakan konsentrasi terbaik pada kombucha buah nanas madu Subang dalam menghambat keempat bakteri uji yaitu terdiri dari dua bakteri gram positif dan dua bakteri gram negatif, sehingga dapat dimanfaatkan sebagai minuman fungsional terkini pada produk bioteknologi konvensional.
EVALUASI TERAPI NON-FARMAKOLOGI PENYAKIT BATUK DAN PILEK DI KELURAHAN KEMANISAN, CURUG, KOTA SERANG Nur Shobah, Afifah; Noviyanto, Fajrin; Fathiyati, Fathiyati; Fairuza, Filda; Mardianti, Lina; Halimatusyadiah, Leni; Rizqi, Syifa Maulidia; Saefurrohman, Zulius Aditia; Renata, Deo
Jurnal Abdimas Bina Bangsa Vol. 5 No. 2 (2024): Jurnal Abdimas Bina Bangsa
Publisher : LPPM Universitas Bina Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46306/jabb.v5i2.1067

Abstract

Community service on "Evaluation of Non-Pharmacological Therapy for Coughs and Cold in Kemanisan Village, Curug, Serang City" was carried out to determine the community's understanding of the causes, prevention and non-pharmacological therapy to treat coughs and colds. The methods used include counseling, distribution of leaflets, masks and hand sanitizer as well as question and answer sessions. Based on the questionnaire, 87% use traditional medicine when they cough and have a kerokan/kerikan, 86% do it, 72% use a mask and 81% hydrate the body. This activity is important to increase awareness of clean and healthy living in treating coughs and cold
TINGKAT PENGETAHUAN, PERSEPSI, DAN SIKAP MASYARAKAT MUSLIM TERHADAP KEHALALAN OBAT DI DESA SUKARENDAH, SUKARAJA, DAN PADASUKA KABUPATEN LEBAK TAHUN 2024 Noviyanto, Fajrin; Apriliani, Ade; Stiani, Sofi Nurmay; Shobah, Afifah Nur; Halimatusyadiah, Leni
International Journal Mathla’ul Anwar of Halal Issues Vol. 4 No. 2 (2024)
Publisher : Universitas Mathla’ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/ijma.202442.116

Abstract

Halal drugs became a very important issue discussed given th at th ere a re st ill ma ny drugs found that are suspected of containing illegal substances and have not been identified as halal. The aim of this research is to determine the level of knowledge, perception, and public attitude about the validity of drugs and to identify the factors that influence the knowledge, perceived, and attitude of the public about the legitimacy of drugs in the villages of Sukarendah, Sukaraja, and Padasuka. This research uses a descriptive approach model (non eksperimental). On sampling in the population of the village community Sukarendah, Sukaraja, and Padasuka used propability samplings, and collected data through questionnaires. According to the results of the research showed that the level of knowledge about the validity of drugs in the villages of Sukarendah, Sukaraja, and Padasuk very well has a score of 82.86%, the perception of the village people of Skarendha, Sukarasu, and Padasuk to the legitimacy of drugs very good score of 74.29%, the attitude of the people of the towns of Sskarendh, sukaraja and Padassuk very good to the validation of drugs score of 94.3%. Overall, it can be said that the knowledge, understanding, and perception levels of the community of villages are very good.
Pengaruh Konsumsi Buah Pepaya Terhadap Kadar Hemoglobin Pada Ibu Hamil Dengan Anemia Ringan di Wilayah Kerja Puskemas Ciomas Kabupaten Serang Tahun 2025 Fairuza, Filda; Halimatusyadiah , Leni; Marbun, Henny Theresia; Imas, Anisa Ratna Kania
Jurnal Ilmiah Kesehatan Vol 17 No 2 (2025): Jurnal Ilmiah Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/jik.v17i2.2850

Abstract

Latar Belakang: Anemia merupakan salah satu komplikasi yang paling sering terjadi pada kehamilan dan dapat meningkatkan risiko persalinan prematur, berat badan lahir rendah, hingga kematian ibu dan bayi. Upaya penanggulangan anemia pada ibu hamil dapat dilakukan dengan pendekatan nutrisi berbasis pangan lokal, salah satunya buah pepaya (Carica papaya) yang mengandung zat besi, vitamin C, dan asam folat. Tujuan: dalam penelitian ini adalah untuk mengetahui pengaruh konsumsi buah pepaya terhadap kadar hemoglobin pada ibu hamil dengan anemia dan untuk mengetahui kadar hemolobin ibu hamil sebelum dan sesudah pemberian buah papaya. Metode: Penelitian ini menggunakan desain quasi eksperimen dengan pendekatan one group pretest-posttest. Sampel terdiri dari 25 ibu hamil trimester I sampai trimsetser III  dengan anemia ringan yang dipilih dengan teknik total sampling di wilayah kerja Puskesmas Ciomas pada tahun 2025. Intervensi berupa konsumsi buah pepaya sebelum mengkonsumsi buah pepaya ibu hamil diperiksa kadar hemoglobinya dan diberikan selama 14 hari dan data dianalisis menggunakan uji Wilcoxon. Hasil: Berdasarkan hasi uji stasitik ada 25 orang ibu hamil yang mengalami anemia ringan dengan rata-rata kadar haemoglobin 9,19 gr/% melalui test normalitas terdapat peningkatan kadar hemoglobin yang signifikan setelah intervensi, dengan nilai p = 0.000 (p < 0.05), yang menunjukkan bahwa konsumsi buah pepaya efektif dalam meningkatkan kadar hemoglobin pada ibu hamil dengan anemia. Dengan mengkonsumsi buah pepaya selama 14 hari berturut-turut banyaknya buah papaya 140 gram  perhari setelah makan  pagi, ada peningkatan kadar haemoglobin rata-rata 2,5 gr/%. Melalui Test uji Wilcoxon. Buah pepaya California mengandung vitamin C sehingga  baik untuk mengurangi anemia, maka ini layak untuk digunakan sebagai bahan penelitian, sangat berbeda jauh dengan pepaya lokal, yaitu sekitar 78 mg per 100 gram, sedangkan pepaya lokal hanya mengandung sekitar 72 mg per 100 gram.Kesimpulan: Konsumsi buah pepaya berpengaruh secara signifikan terhadap peningkatan kadar hemoglobin pada ibu hamil dengan anemia. Pemberian buah pepaya dapat dipertimbangkan sebagai intervensi nutrisi alami dalam pencegahan dan penanganan anemia pada ibu hamil.
Comparative Analysis of Cost Effectiveness of Ceftriaxone and Cefotaxime Antibiotic Therapy in Inpatients with Typhoid Fever in Aulia Pandeglang Regional Hospital in 2023 Yusransyah, Yusransyah; Rustiyani, Risa; Nurani, Agnes Wieanita; Stiani, Sofi Nurmay; Udin, Baha; Halimatusyadiah, Leni
Journal of Experimental and Clinical Pharmacy (JECP) Vol 5, No 2 (2025): August 2025
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v5i2.1436

Abstract

Typhoid fever is still a significant health problem for children in developing countries, including Indonesia. This disease is caused by infection with Salmonella Typhi bacteria, which is a Gram-negative bacteria and requires treatment with antibiotics. The use of antibiotics usually takes up a large portion of the hospital treatment budget. This study aims to compare the cost-effectiveness between two types of antibiotics, namely ceftriaxone and cefotaxime, in typhoid fever patients at Aulia Pandeglang Hospital, and to find the most cost-efficient treatment. This study is descriptive and observational, with retrospective data collection. The data used came from medical records and cost records of inpatients with typhoid fever in children aged 1 to 11 years at Aulia Pandeglang Hospital in 2023. A total of 20 patients met the study criteria. The outcomes measured in this study were the average length of stay in the hospital. The cost components calculated consisted of direct medical costs, such as drug costs, action costs, inpatient costs, medical device costs, and laboratory fees. The analysis was conducted from the payer's perspective. The results showed that the cost for the effectiveness of using ceftriaxone and cefotaxime was IDR 15,264 and IDR 18,265, with an ICER of IDR 257.9 to increase the effectiveness of cefotaxime. The conclusion of this study is that ceftriaxone is a more cost-effective antibiotic.
Co-Authors Afifah Nur Shobah Afifah Nur Shobah Afifah Nur Shobah Afifah Nur Shobah Agustiansyah, Lucky Dita Agustin, Siti Alfi Rahmadhant Alya Widianti Amelia, Rosni Andri Harpan Anggarani Prihantiningsih Prihantiningsih Anisa Ratna Kania Imas Annisa Maulidya Nur Utami Apriliani, Ade Baha Udin Cahya Skania, Pratiwi Deo Renata Desi Permatasari Desi Trisnawati Dewi Intan Sri Rahayu Dinda Ayu Aprilia Qurotul Ain Dini Gharrat Fanai Dwinda Sari Dwiyarina Margarisa Elsa Agustin Elva Febri Ashari Endah Endah Endang Safitri Eva Kholifah Evah Fazhari Fajrin Noviyanto Fajrin Noviyanto Fajrin Noviyanto Fajrin Fajrin Noviyanto, Fajrin Fathiyati, Fathiyati Filda Fairuza Giastami, Salma Nur Hanifah Dwi Safitri Hendra Jaya Henny Theresia Marbun Ika Lustiani Imas, Anisa Ratna Kania Indah Ayu Nur Hasana Iqlima Raina Khairunnisa Isti Dwi Pruschia Jamilah Jamilah Lilis Zuniawati Setianingsih Lina Mardianti Lustiani, Ika M. Fariz Fadillah M. Fariz Fadillah M. Fariz Fadillah Mardianto Marbun, Henny Theresia Meila Pertiwi Muhammad Amin Nasution Muhammad Andry Mutia Muhardiyanti Nina Yuliana Sari Nina Yuliana Sari Nur Shobah, Afifah Nur Utami, Annisa Maulidya Nurani, Agnes Wieanita Nuria Fitri Adista Oktaviana Hadi, Agriyaningsih R Noucie Septriliyana Renata, Deo Renditya Ismiyati Rima Herawati Rina Octavia Rinditya Lutfiah Syafa Kurnadi Rizqi, Syifa Maulidia Rustiyani, Risa Saefurrohman, Zulius Aditia Safitri, Endang Selvi Maria Ulfah Shobah, Afifah Nur Siska Siska Siti Agustin Stiani, Sofi Nurmay Suprawati Suprawati Syifa Maulidia Rizqi Sylvi Addini Tanjung, Siti Aisiyah Teguh Ardianto Theresia Marbun, Henny Yensi Widiasti Agustine Yusransyah, Yusransyah