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Senyawa Fucoidan Pada Teripang Laut Untuk Pengobatan Diabetes Mellitus: Sebuah Tinjauan Pustaka Wina Arsylia Fakar
Jurnal Medika Hutama Vol. 5 No. 01 Oktober (2023): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Abstract

Diabetes Mellitus (DM) is a chronic disease characterized by blood glucose (blood sugar) levels exceeding normal, namely blood sugar levels at or above 200 mg/dl, and fasting blood sugar levels above or equal to 126 mg/dl. In the last few decades, the content of sea cucumber secondary metabolites has been widely studied, such as inhibiting the growth of new blood vessels, preventing excessive blood clotting, having antibacterial, anti-inflammatory, anticancer properties, including antidiabetes One of the sea cucumber compounds is Fucoidan, which is an acidic polysaccharide consisting of fucose monosaccharides and its chemical structure differs depending on the type of sea cucumber. Fucoidan has been widely proven to have potential in the treatment of diabetes.
Trauma Vaskular: Patofisiologi, Manifestasi Klinis, Diagnosis dan Penatalaksanaan Palna, Zhayyin; I Gede Aditya Satrya Bhuwana Cakra; Irsyadina Hasana Bharata; Khaula Karima; Salsabila Chauna; Wina Arsylia Fakar; Maz Isa Anshori Arsatt
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.3381

Abstract

Vascular trauma is an injury involving the circulatory system, particularly blood vessels, disrupting the body's balance and being a leading cause of morbidity and mortality. The extremities are the most common locations for vascular trauma, especially the femoral artery, popliteal artery, and brachial artery. Signs and symptoms of vascular trauma in body limbs are described as hard and soft signs. Hard signs found in patients indicate the need for surgical intervention, while patients with soft signs require further diagnostic imaging for confirmation. Management should consider the golden period (6 to 8 hours) by controlling bleeding with resuscitative endovascular balloon occlusions (REBOA), minimizing ischemic events in the distal part of the trauma, and preventing compartment syndrome. Surgical intervention is performed to achieve functional recovery and salvage the affected vascular area. Surgical procedures that can be performed in cases of vascular trauma include vascular grafting, vascular ligation, and temporary intravascular shunt (TIVS).