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Graves Disease: Diagnosis dan Tatalaksana Lestary, Ayundha Rizky; Fatikha Rudia Ahda; I Gede Aditya Satrya Bhuwana Cakra; Ni Made Sri Padma Puspita; Eva Triani
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2754

Abstract

Abstract: Hyperthyroidism is an increase in the amount of thyroid hormone synthesis and secretion by the thyroid gland. Graves Disease (GD) is the most common cause of hyperthyroidism. Graves Disease (GD) is more common in women than men and in patients with a family history of GD. Graves Disease can also be triggered by environmental factors such as stress, smoking, infection, and exposure to iodine. Graves Disease manifests in the form of the Merseburger triad consisting of thyrotoxicosis, diffuse goiter, and ophthalmopathy (orbitopathy) with symptoms of agitation, palpitations, and muscle weakness. In making the diagnosis of GD, 2 tests are carried out, namely a thyroid function test which consists of examinations to diagnose hypothyroidism, namely Wayne index scoring, TSH test, and FT4 as well as tests to distinguish GD from other causes of hyperthyroidism, namely TRab, radioactive iodine uptake scan with I-123 or I-131, thyroid ultrasound with doppler, T3/T4 ratio values, and CT or MRI. The goal of treatment for GD is to control and improve the condition based on the pathophysiology of GD, namely the antigen-antibody reaction in the thyroid gland. Modalities for the treatment of GD consist of anti-thyroid drugs, surgery, and radioactive iodine (RAI) treatment with sodium-131(131I). The choice of treatment is based on the severity of thyrotoxicosis, age, thyroid size, availability of modalities, response to treatment, and other comorbidities.
Graves Disease: Diagnosis dan Tatalaksana Lestary, Ayundha Rizky; Fatikha Rudia Ahda; I Gede Aditya Satrya Bhuwana Cakra; Ni Made Sri Padma Puspita; Eva Triani
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2754

Abstract

Abstract: Hyperthyroidism is an increase in the amount of thyroid hormone synthesis and secretion by the thyroid gland. Graves Disease (GD) is the most common cause of hyperthyroidism. Graves Disease (GD) is more common in women than men and in patients with a family history of GD. Graves Disease can also be triggered by environmental factors such as stress, smoking, infection, and exposure to iodine. Graves Disease manifests in the form of the Merseburger triad consisting of thyrotoxicosis, diffuse goiter, and ophthalmopathy (orbitopathy) with symptoms of agitation, palpitations, and muscle weakness. In making the diagnosis of GD, 2 tests are carried out, namely a thyroid function test which consists of examinations to diagnose hypothyroidism, namely Wayne index scoring, TSH test, and FT4 as well as tests to distinguish GD from other causes of hyperthyroidism, namely TRab, radioactive iodine uptake scan with I-123 or I-131, thyroid ultrasound with doppler, T3/T4 ratio values, and CT or MRI. The goal of treatment for GD is to control and improve the condition based on the pathophysiology of GD, namely the antigen-antibody reaction in the thyroid gland. Modalities for the treatment of GD consist of anti-thyroid drugs, surgery, and radioactive iodine (RAI) treatment with sodium-131(131I). The choice of treatment is based on the severity of thyrotoxicosis, age, thyroid size, availability of modalities, response to treatment, and other comorbidities.
Trauma Vaskular: Patofisiologi, Manifestasi Klinis, Diagnosis dan Penatalaksanaan Palna, Zhayyin; I Gede Aditya Satrya Bhuwana Cakra; Irsyadina Hasana Bharata; Khaula Karima; Salsabila Chauna; Wina Arsylia Fakar; Maz Isa Anshori Arsatt
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.3381

Abstract

Vascular trauma is an injury involving the circulatory system, particularly blood vessels, disrupting the body's balance and being a leading cause of morbidity and mortality. The extremities are the most common locations for vascular trauma, especially the femoral artery, popliteal artery, and brachial artery. Signs and symptoms of vascular trauma in body limbs are described as hard and soft signs. Hard signs found in patients indicate the need for surgical intervention, while patients with soft signs require further diagnostic imaging for confirmation. Management should consider the golden period (6 to 8 hours) by controlling bleeding with resuscitative endovascular balloon occlusions (REBOA), minimizing ischemic events in the distal part of the trauma, and preventing compartment syndrome. Surgical intervention is performed to achieve functional recovery and salvage the affected vascular area. Surgical procedures that can be performed in cases of vascular trauma include vascular grafting, vascular ligation, and temporary intravascular shunt (TIVS).