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All Journal Majalah Biomorfologi (Biomorphology Journal) Surabaya Biomedical Journal
Fitria Kusumastuti
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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AGE, SEX, AND TYPES OF OCCUPATION WITH HISTOPATHOLOGICAL TYPES IN PATIENTS WITH OCULAR SURFACE SQUAMOUS NEOPLASIA (OSSN) IN A TERTIARY HOSPITAL IN SURABAYA, INDONESIA Stella Agatha Widjaja; Delfitri Lutfi; Linda Dewanti; Alphania Rahniayu; Fitria Kusumastuti
Majalah Biomorfologi Vol. 34 No. 2 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i2.2024.74-82

Abstract

Highlights The histopathological types of OSSN were significantly associated with age and occupation. The study's findings enhance the understanding of OSSN in Indonesia and emphasize the importance of UV exposure, occupation, and age in its development.   Abstract Background:  Ocular Surface Squamous Neoplasia (OSSN) is a spectrum of tumors affecting the conjunctiva and cornea, in which a more invasive type of OSSN has a higher recurrence rate. As a tropical country, Indonesia is constantly exposed to intense ultraviolet (UV) radiation, the main risk factor for OSSN. Despite this, there are very few studies regarding OSSN in Indonesia. Objective:  This study aimed to analyze the association between sociodemographic characteristics such as age, sex, and types of occupation (outdoor and indoor) and histopathological types of OSSN to fill the gap in research and contribute to early diagnostic strategies. Material and Method: Sociodemographic and histopathological data were extracted from the medical records of patients who were histopathologically diagnosed with OSSN at Dr. Soetomo General Hospital from 2017 to 2021. Data from 88 samples that met the inclusion and exclusion criteria were classified and analyzed with descriptive statistics and a two-sided Fisher's exact test using SPSS version 27.0 (IBM Corp., Armonk, N.Y., USA). Result: The exact test results of the two-sided fisher revealed a statistically significant relationship between age (p = 0.0004) and occupation type (p = 0.049) with histopathological types of OSSN. However, no significant association was found between sex and histopathological types of OSSN (p = 0.130). Conclusion: Age and occupation were found to have a significant association with the histopathological types of OSSN, reinforcing the need for further exploration of its strength and nature to be considered by future researchers.
Kejadian Ablasio Retina Regmatogen Pada Miopia Tinggi: Sebuah Laporan Kasus Ni Luh Ayu Made Intan Edyassari Putriutami; Fitria Kusumastuti; I Ketut Edy Sudiarta
Surabaya Biomedical Journal Vol. 2 No. 1 (2022): September
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v2i1.44

Abstract

Latar Belakang: Ablasio retina adalah salah satu kelainan mata yang dapat mengancam penglihatan dan dapat menyebabkan kebutaan. Ablasio retina regmatogen merupakan jenis ablasio yang paling sering ditemukan dan memerlukan penatalaksanaan bedah yang segera dan komprehensif untuk mencegah terjadinya gangguan penglihatan dan kebutaan yang permanen. Insiden kasus ablasio retina regmatogen secara global adalah 1 dibanding 10.000 kasus per tahunnya. Miopia tinggi merupakan salah satu faktor resiko dari ablasio retina regmatogen. Ilustrasi Kasus: Pasien laki-laki berusia 25 tahun datang ke rumah sakit dengan keluhan mata kanan kabur mendadak dan pandangan seperti tertutup tirai hitam sejak 4 jam sebelum ke rumah sakit setelah mengangkat benda berat dengan riwayat penggunaan kacamata OD S-11.0 D dan OS S-10.0 D. Pada pemeriksaan oftalmologis didapatkan visus OD light perception (+) dengan total detach pada retina, retinal tear pada jam 11-12, macula off, RM (-). Pasien menjalani vitrektomi pars plana dengan tamponade perfluorocarbon dan endolaser. Pasien mengalami peningkatan tajam penglihatan setelah menjalani tindakan tersebut. Kesimpulan: Seorang laki-laki berusia 25 tahun dengan riwayat miopia tinggi mengalami ablasio retina regmatogen setelah melakukan aktifitas mengangkat benda berat. Tindakan vitrektomi pars plana dengan tamponade perfluorocarbon dan endolaser telah dilakukan pada pasien ini dan memberikan hasil attachment dan hasil tajam penglihatan yang relatif baik.
Co-Authors Alphania Rahniayu I Ketut Edy Sudiarta Linda Dewanti Lutfi, Delfitri Ni Luh Ayu Made Intan Edyassari Putriutami Stella Agatha Widjaja