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Patient adherence and factors associated with short-term oral antibiotic use for acute respiratory infections (ISPA) in Wedi primary health care Putri, Aristhasari; Septyasari, Avanilla Fany; Ridhwan, Adib Muhammad
Borobudur Pharmacy Review Vol. 5 No. 2 (2025): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i2.14513

Abstract

Upper respiratory tract infection (URTI) is a common illness in Indonesia caused by microorganisms, caused by microorganisms that affect the upper respiratory tract. Short-term antibiotic therapy is frequently prescribed, but many patients do not adhere to this treatment. Non-compliance often occurs because patients feel better, forget to take their medication, or do not follow the prescribed regimen properly. This can lead to poor clinical outcomes and an increased risk of bacterial resistance. This study was conducted to to assess the level of adherence and contributing factor among URTI patients to short-term oral antibiotic therapy. A cross-sectional research design was employed, utilizing a structured questionnaire for data collection. The sampling method applied was purposive sampling, which included a cohort of 31 patients with URTI who were prescribed short term antibiotics. The results showed that 77.4% of respondents were compliant, while 22.6% were non-compliant. Factors that significantly associated with adherence included educational level and occupation (p < 0.05), while age did not show a significant relationship (p > 0.05). Another factors influencing non-adherence included inadequate information provided by healthcare professionals, busy schedules, premature discontinuation of therapy due to perceived recovery, lack of family support, and difficulty swallowing medication. Pharmacists can play a significant role in improving compliance by providing clear information and utilizing reminder tools to assist patients in taking their medication as prescribed.
Evaluasi Komparatif Asam Sitrat Pada Beberapa Kultivar Mangga Lokal (Mangifera indica L.) dengan Metode Titrasi Alkalimetri Choiril Hana Mustofa; Elsa Epilia Duri; Avanilla Fany Septyasari; Aristhasari Putri
CERATA Jurnal Ilmu Farmasi Vol 17 No 1 (2026): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v17i1.2449

Abstract

Citric acid is an organic secondary metabolite found in fruit and is important in determining the sensory profile and biochemical stability of mango (Mangifera indica L.). This observational study aimed to quantitatively measure the prevalence of citric acid in three local mango varieties: Harumanis, Indramayu, and Manalagi. The methodology employed included qualitative identification through a precipitation reaction with calcium chloride (CaCl₂) and quantitative determination using an alkalimetric method. Qualitative test results on all three samples confirmed the presence of citric acid in all samples through the formation of calcium citrate precipitates. Quantitative analysis showed that the average citric acid content in Harumanis mangoes was 0.69%, Indramayu mangoes 0.98%, and Manalagi mangoes 0.92%. These findings indicate that the Indramayu variety has the highest citric acid content, which implies a potential longer shelf life compared to other varieties.
Gambaran Tingkat Kepatuhan Minum Obat Anti Hipertensi pada Pasien Hipertensi di Desa Kujon Kecamatan Ceper Kabupaten Klaten Avanilla Fany Septyasari; Aristhasari Putri; Sutaryono Sutaryono; Maherawati Noni
CERATA Jurnal Ilmu Farmasi Vol 14 No 2 (2023): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v14i2.906

Abstract

Hipertensi merupakan suatu kondisi terjadinya peningkatan tekanan darah sistolik dan diastolik yaitu >140/90 mmHg. Hipertensi merupakan penyakit degeneratif yang membutuhkan terapi jangka panjang dan tekanan darah harus terkontrol, dan untuk mencapai tekanan darah yang terkontrol dibutuhkan managemen terapi yang baik, salah satunya adalah kepatuhan dalam meminum obat antihipertensi. Kepatuhan dan ketidakpatuhan terapi akan mempengaruhi terkontrolnya tekanan darah pasien. Tujuan penelitian ini untuk mengetahui tingkat kepatuhan pasien meminum obat antihipertensi di Desa Kujon, Ceper, Klaten. Penelitian ini merupakan penelitian deskriptif observasional. Teknik pengambilan sampel menggunakan metode purposive sampling, dan kuesioner MARS-10. Responden yang terlibat dalam penelitian ini sejumlah 57 responden. Hasil penelitian ini menunjukkan sebagian besar responden (59,65%) memiliki tingkat kepatuhan sedang / cukup patuh dalam meminum obat antihipertensi
Tingkat Kepatuhan dan Faktor yang Mempengaruhi Penggunaan Obat Antihipertensi pada Pasien Lansia di Posyandu Lansia Desa Drono Aristhasari Putri; Avanilla Fany Septyasari; Belinda Apriliana
CERATA Jurnal Ilmu Farmasi Vol 15 No 2 (2024): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v15i2.1493

Abstract

The incidence of hypertension in the elderly has increased, which is caused by several factors that affect the level of compliance. This study was conducted to determine the level of compliance and factors that influence the use of antihypertensive drugs in patients at the elderly Posyandu Drono Village. This study used purposive sampling technique and questionnaire instrument of MARS-10, correlation analysis was performed with Chi-square test. The results showed that the level of patient compliance in the elderly Posyandu of Drono Village was not compliant (71.4%). Factors that have a correlation with compliance with the use of antihypertensive drugs are educational factors, with a value of p = 0,002 and family support factors with a value of p = 0,045. Providing comprehensive counseling about the desired outcomes, potential side effects, and proper medication usage can enhance patient knowledge, ultimately improving patient adherence. Moreover, family support can promote better adherence in elderly patients.
Tingkat Pengetahuan Tentang Penggunaan Antibiotik Masyarakat Desa Kajoran Kecamatan Klaten Selatan Avanillla Fany Septyasari; Aristhasari Putri; Hanna Nikma Fatin; Choiril Hana Mustofa; Muchson Arrosyid
CERATA Jurnal Ilmu Farmasi Vol 16 No 2 (2025): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v16i2.2102

Abstract

Antibiotics are one type of medication used to treat bacterial infections. The use of antibiotics will ensure successful treatment, but currently there are many cases of antibiotic resistance caused by the inappropriate use of antibiotics. The purpose of this study is to determine the level of knowledge among the community of Kajoran Village, South Klaten District, regarding the use of antibiotics. The method used was descriptive observational with a cross-sectional approach and purposive sampling technique. The research instrument used a questionnaire and analysis using univariate analysis. The results showed that the level of knowledge among the community in Kajoran Village, South Klaten District was in the category of sufficient knowledge regarding the use of antibiotics (42.3%).
Antipyretic effect of Cymbopogon citratus ethanol extract on yeast-induced fever in mice Septyasari, Avanilla Fany; Putri, Aristhasari; Sholihatun, Anik
Borobudur Pharmacy Review Vol. 5 No. 2 (2025): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i2.15115

Abstract

Lemongrass (Cymbopogon citratus) contains several secondary metabolites, one of which is flavonoids that have the ability to inhibit the activity of cyclooxygenase enzymes. Aims of this study is to determine the efficacy of lemongrass stem ethanol extract (Cymbopogon citratus) as an antipyretic and to determine the minimum effective dose for reducing fever in mice (Mus musculus) induced by yeast. The type of study is an experimental laboratory study, divided into 5 treatment groups, 0.5% CMC Na, paracetamol, lemongrass stem extract at doses of 4 mg/20 g, 6 mg/20 g, and 8 mg/20 g. Fever in mice was induced by subcutaneous injection of a 1.5% yeast solution. Rectal temperature measurements were taken at regular intervals at 30, 60, 90, 120, 150, and 180 minutes. The test results showed that the ethanol extract of lemongrass stem at a dose of 4 mg/20 g was able to reduce the fever-induced temperature of mice by 0.78°C from the fever temperature, while the 8 mg/20 g dose of lemongrass extract exhibited antipyretic effects similar to paracetamol.
EDUKASI KONSUMSI TABLET TAMBAH DARAH UNTUK PENCEGAHAN ANEMIA REMAJA PUTRI DI SMA NEGERI 1 KARANGNONGKO Aristhasari Putri; Ayu Jenita Dwi Saputri; Nur Halimah Rika Astuti; Salsabila Suryaningrum; Vika Yuliana Andita Sari; Zesicha Nur Laily
WASATHON Jurnal Pengabdian Masyarakat Vol 4 No 2 (2026)
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/wasathon.v4i2.2550

Abstract

Anemia remains a common health problem among adolescent girls due to increased iron requirements during the growth period and blood loss during menstruation. Poor adherence to Iron Supplement Tablet (IST) consumption is one of the factors contributing to the increased risk of anemia. This community service program aimed to improve adolescent girl’s knowledge and awareness of the importance of IST consumption as an effort to prevent anemia. The program involved 30 female students from SMA Negeri 1 Karangnongko and was conducted throught health education using PowerPoint presentations, posters, leaflets, interactive discussions, question and answer sessions, and educational games. The effectiveness of the program was evaluated using pre-test and post-test asessements, followed by the Wilcoxon signed-rank test. The results showed that the mean knowledge score increased from 92.67 to 94.67, although the improvement was not statistically significant (p=0.574). Nevertheless, the program successfully strengthened participant’s understanding and increased their awareness of the importance of regular IST consumption as a strategy to prevent anemia among adolescent girls.