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All Journal Journal of Clinical Pharmacy and Pharmaceutical Science Jurnal Kesehatan Maluku Husada
Maritje S.J Malisngorar
STIKes Maluku Husada
Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Formulasi Emulgel Ekstrak Daun Kopasanda (Chromolaena odorata L.) Menggunakan Carbopol 940 Sebagai Gelling Agent Nabila Aulia; Lukman La Basy; Ety Dusra; Dzulfikri Mewar; Maritje S.J Malisngorar
JURNAL KESEHATAN MALUKU HUSADA Vol 3, No 2 (2025): JULI-DESEMBER 2025
Publisher : STIKes Maluku Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/jkmh3205

Abstract

Daun kopasanda (Chromolaena odorata L.) mengandung flavonoid, saponin, dan tanin yang berperan sebagai antibakteri, antiinflamasi, dan antioksidan sehingga berpotensi mempercepat penyembuhan luka. Untuk meningkatkan efektivitas dan kenyamanan aplikasi topikal, ekstrak daun kopasanda diformulasikan dalam bentuk emulgel dengan Carbopol 940 sebagai gelling agent. Penelitian ini bertujuan memformulasikan ekstrak daun kopasanda menjadi emulgel serta mengetahui pengaruh variasi konsentrasi Carbopol 940 sebagai gelling agent terhadap stabilitas fisik sediaan emulgel ekstrak daun kopasanda (Chromolaena odorata L.). Metode penelitian bersifat eksperimental laboratorium. Ekstrak diperoleh melalui maserasi etanol 70%, kemudian diformulasikan menjadi emulgel dengan variasi konsentrasi Carbopol 940 (0,5%, 1%, 1,5%, dan 2%). Evaluasi mutu fisik meliputi uji organoleptik, pH, viskositas, daya sebar, dan daya lekat. Data dianalisis menggunakan uji Kruskal-Wallis. Hasil menunjukkan seluruh formula stabil secara organoleptik. Nilai pH rata-rata berada dalam rentang fisiologis kulit (F1 = 6; F2 = 5; F3 = 5; F4 = 5). Viskositas meningkat seiring kenaikan konsentrasi (F1 = 695 cps; F2 = 31.444 cps; F3 = 44.636,7 cps; F4 = 66.461,3 cps). Uji daya sebar rata-rata berkisar 6 cm (F1), 5,5 cm (F2), 5 cm (F3), hingga 4 cm (F4). Uji daya lekat menunjukkan peningkatan signifikan, dari 1,7 detik (F1), 2,6 detik (F2), 4,3 detik (F3) hingga 5,3 detik (F4). Analisis Kruskal-Wallis memperlihatkan perbedaan signifikan (p < 0,05) pada viskositas, daya sebar, pH dan daya lekat antar formula. Sehingga dapat disimpulkan bahwa ekstrak daun kopasanda dapat diformulasikan menjadi emulgel yang stabil, dengan Carbopol 940 konsentrasi 1,5% sebagai formula paling optimal.
Pengaruh Edukasi Dengan Audio Visual Terhadap Pengetahuan Ibu Tentang Stunting Desa Teluti Baru Tahun 2023 Maritje S.J Malisngorar; Ety Dusra; Siti Nadya Silawane
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 4 No. 2 (2025): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i2.45

Abstract

Stunting is a condition of growth failure that occurs in children under five years of age (bavi under five years) as a result of chronic malnutrition so that children look short at their age. Stunting occurs in the critical period from the womb, 1000 HPK to the age of two years. if not addressed it will have a permanent impact because stunting is irreversible or cannot be corrected. This study is to determine the effect of education with audio visual media on mothers' knowledge about stunting in Telutih Baru Village, Tehoru District.This study used Pre-Experiment method with one group pre-test and post-test design. The population in this study were 45 mothers who had a 2-year-old bailta. While the sample in this research is 45 mothers who have toddlers aged 2 years in Teluti Baru Village, Tehoru District. The sampling technique used total sampling technique The research instrument used a questionnaire in the form of statements, the variable in this study was a single variable, namely maternal knowledge. The analysis used in this study was the Wilcoxon Test.analysis of the effect of education with Audio Visual media on maternal knowledge about stunting in Teluti Baru Village, Tehoru District in 2023 from the results of the Wilcoxon Test Respondents' knowledge decreased 0, knowledge remained 0, Respondents' knowledge increased 45.
Co-Authors Dzulfikri Mewar Ety, Dusra Lukman La Basy Nabila Aulia Siti Nadya Silawane