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Activity Test of Facial Wash Formulation Containing Ethanol Extract of Patikala Fruit (Etlingera elatior) Against the Growth of Propionibacterium acnes Muthmainnah Thalib; Istianah Purnamasari; Nirwana Nirwana
International Journal Of Health Science Vol. 5 No. 1 (2025): : International Journal of Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v5i1.6080

Abstract

Acne (acne vulgaris) in Indonesia, as a country with a tropical climate, has a high prevalence of the disease. This is caused by tropical climate conditions that support the growth of bacteria, parasites, and fungi. Propionibacterium acnes is another organism involved in skin pathogenesis. One of the plants that has antibacterial properties is the patikala fruit (Etlangiera elatior) as an anti-acne agent so it can be formulated as a facial wash preparation because it has antioxidant and antimicrobial activity. This study aims to determine whether the ethanol extract of the patikala fruit (Etlangiera elatior) can be formulated into a facial wash preparation that has good physical stability and has antibacterial activity at concentrations of 3%, 6% and 9%. This research method is a laboratory experiment that aims to formulate a facial wash preparation based on the ethanol extract of the patikala fruit (Etlangiera elatior) and test its antibacterial activity against the bacteria that causes acne, namely Propionibacterium acnes. The most effective facial wash preparation of ethanol extract of patikala fruit (Etlingera elatior) in inhibiting the growth of Propionibacterium acnes bacteria is a concentration of 9% with an inhibitory power of 16.43 mm, which is included in the strong category.
FORMULASI  DAN KARAKTERISASI SABUN ANTISEPTIK PADAT BERBASIS MINYAK JELANTAH DIPERKAYA EKSTRAK ETANOL DAUN BIDARA CINA (Ziziphus jujuba) UNTUK PEMANFAATAN BERKELANJUTAN. Zakiah Thahir; Yuyun Sri Wahyuni; Hernawati Basir; Istianah Purnamasari; Adrival Darwin; Aisyah; Indah Lestari
Jurnal Kesehatan Yamasi Makassar Vol 10 No 1 (2026): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/aap2gh31

Abstract

Minyak jelantah merupakan limbah rumah tangga yang berpotensi mencemari lingkungan, sementara daun bidara cina (Ziziphus jujuba) dikenal memiliki ragam aktivitas biologi, termasuk antibakteri. Pemanfaatan kedua komponen ini dalam formulasi sabun antiseptik padat dapat memberikan nilai tambah dan solusi berkelanjutan. Tujuan: Penelitian ini bertujuan untuk memformulasikan sediaan sabun antiseptik padat berbasis minyak jelantah dengan penambahan ekstrak etanol daun bidara cina yang memenuhi persyaratan mutu SNI, serta mengevaluasi karakteristik fisik, kimia, dan aktivitas antibakterinya. Metode: Minyak jelantah dimurnikan dengan arang sabut kelapa. Ekstrak etanol daun bidara cina ditambahkan ke dalam sabun pada konsentrasi 5% (F1) dan 10% (F2), dibandingkan dengan blanko (F0). Pengujian meliputi organoleptik (bentuk, warna, aroma), pH, tinggi busa, kadar air, asam lemak bebas, dan alkali bebas. Aktivitas antibakteri diuji terhadap Staphylococcus aureus, Staphylococcus epidermidis, dan Propionibacterium acne. Hasil: Semua formula sabun menunjukkan karakteristik organoleptik yang baik (padat, aroma khas) dengan variasi warna sesuai konsentrasi ekstrak. Nilai pH (9.7-10.1) dan tinggi busa (59.67-75.33 mm) memenuhi SNI. Kadar air (8.3-9.31%) dan asam lemak bebas (2.0-2.3%) juga memenuhi standar. Namun, kadar alkali bebas Formula 2 (0.2%) melebihi batas SNI (<0.1%). Semua formula dengan ekstrak menunjukkan zona hambat terhadap ketiga bakteri uji, dan zona hambat meningkat seiring peningkatan konsentrasi ekstrak (terbesar pada 10%) sehingga dapat disimpulkan bahwa  Sabun antiseptik padat berbasis minyak jelantah dan ekstrak etanol daun bidara cina berhasil diformulasikan dan memenuhi sebagian besar standar mutu SNI serta menunjukkan aktivitas antibakteri yang baik, meskipun Formula 2 memerlukan optimasi lebih lanjut terkait kadar alkali bebas.
PENGARUH EKSTRAK ETANOL DAUN KELAPA SAWIT (Elaeis guineensis Jack.) TERHADAP PERTUMBUHAN Staphylococcus aureus dan Escherichia coli BERDASARKAN METODE KLT-BIOAUTOGRAFI Istianah Purnamasari; Muhammad Taufiq Duppa; Syafruddin Syafruddin; Sitti Nurjanna; Anshari Masri; Hernawati Basir; Ermawati Ermawati
Jurnal Kesehatan Yamasi Makassar Vol 10 No 2 (2026): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/44bza773

Abstract

This study aims to determine the antibacterial activity of ethanol extract of oil palm leaves (Elaeis guineensis Jack.) against the growth of Staphylococcus aureus and Escherichia coli and to determine the compounds from ethanol extract of oil palm leaves (Elaeis guineensis Jack.) that can provide antibacterial based on TLC-Bioautography analysis. This study tested the antibacterial activity of ethanol extract of oil palm leaves (Elaeis guineensis Jack.). Ethanol extract of oil palm leaves was obtained through the maceration method. Then the activity test was carried out by TLC-Bioautography against Staphylococcus aureus and Escherichia coli bacteria. The results of the separation of compounds by Thin Layer Chromatography (TLC) using n-hexane: ethyl acetate (7: 3) eluent. The results of the TLC-Bioautography test showed that spots at Rf values ​​0.92; Rf 0.85; Rf 0.74; Rf 0.7; Rf 0.63 and Rf 0.52 can provide inhibitory activity against Staphylococcus aureus and at Rf values ​​​​of 0.92; Rf 0.85 can provide inhibitory activity against Escherichia coli. The results of the identification of chemical components gave positive results in the appearance of flavonoid spots at Rf values ​​​​of 0.92; Rf 0.85 and alkaloids at Rf values ​​​​of 0.92; Rf 0.74.