Asti Pratiwi
Fakultas Farmasi, Institut Kesehatan Medistra Lubuk Pakam, Indonesia

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Uji Aktivitas Ekstrak Biji Asam Jawa (Tamarindus indica) terhadap Asam Urat Mencit Putih Jantan (Mus Musculus) Induksi Kalium Oksonat Asti Pratiwi; Aminah Syarifuddin; Cucu Arum Dwi Cahya; Melinda Sari
Jurnal Indah Sains dan Klinis Vol 4 No 2 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i2.01

Abstract

Background: The Tropical Tamarind Plant has great economic value and benefits for society, from the stems to the leaves it can be used to treat diseases, such as fever, dyspepsia and even gonorrhoea. The chemical components of Tamarind seeds include alkaloids, saponins, flavonoids, glycosides, malic acid, tartrate, pectin, arabinose, xylose, galactose and glucose. Objective: The study was directed to determine the activity of ethanol extract from tamarind seeds in reducing uric acid in mice. Methods: Preparation of dry extract of Tamarind seeds (EKBAJ), phytochemical screening, and testing the activity of reducing uric acid in mice induced by potassium oxonate at various concentrations of EKBAJ. Measure the levels with Easy Touch GCU. Results: EKBAJ can inhibit mouse uric acid synthesis. The higher the concentration of EKBAJ, the greater the effect on reducing uric acid levels. Conclusion: A concentration of 200 mg/kgBW had the greatest effect on reducing uric acid in mice.
Kuantifikasi Vitamin C Petai Cina (Leucaena leucocephala) dengan Spektrofotometri UV-Vis Asti Pratiwi; Aminah Syarifuddin; Cucu Arum Dwi Cahya; Sri Rahayu
Jurnal Indah Sains dan Klinis Vol 4 No 3 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i3.01

Abstract

Background: Vitamin C is very soluble in water and is always used for additional nutrition in the form of supplements. This vitamin is needed by the body because it can increase the body's ability to fight disease and function as a neutralizer of radical particles found in the body, usually referred to as antioxidants. One of them is the Petai Cina plant which is used by the community as a savory flavor in dishes, and can also be used as traditional medicine. Objective: To determine the presence and levels of vitamin C in Petai Cina in the Lubuk Pakam regional market. with quality and quantity analysis. Method: Samples were analyzed qualitatively using a specific color reagent for vitamin C and quality was determined using UV spectrophotometry. Results: The standard vitamin C wavelength is 224.5 nm at a concentration of 4 ppm with the regression equation y = 0.0339x + 0.3922. Qualitatively, it is proven that there is vitamin C in Petai Cina with a quantity of 0.1095 mg/mL. Conclusion: Vitamin is found in Petai Cina with a quantity of 0.1095 circulating in the Lubuk Pakam market