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All Journal JPP Jurnal Kesehatan Poltekkes Palembang Community Engagement and Emergence Journal (CEEJ)
Nur Arifah
Universitas Indo Global Mandiri
Humanities Economics, Econometrics & Finance Education Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health

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Upaya Menuju Zero Hunger Melalui Pemanfaatan Potensi Kampung KB Sungai Jawi Dengan Beternak Lele Bioflok Dan Kankung Hidroponik Tien Yustini; Nur Arifah; Atidira Dwi Hanani
Community Engagement and Emergence Journal (CEEJ) Vol. 5 No. 2 (2024): Community Engagement & Emergence Journal (CEEJ)
Publisher : Yayasan Riset dan Pengembangan Intelektual

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37385/ceej.v5i2.5721

Abstract

Pengabdian kepada Masyarakat ini bertujuan  untuk memberikan edukasi kepada kader kampung KB Cempaka, agar dapat memanfaatkan potensi sekitar guna menghasilkan produk, ternak lele bioflok dan kangkung hidroponik  dalam satu wadah. Kegiatan Program PkM ini dilaksanakan di balai Kampung KB Cempaka dan dihadiri kader dan pengurus KKB Cempaka sebanyak 20 orang. Sebelum dan sesudah kegiatan dilakukan pra test dan post test.  Hasil PkM ini diharapkan memberikan manfaat: 1) mengedukasi pengurus dan kader kampung KB untuk memanfaatkan kembali potensi ekonomi yang ada di wilayah KKB Cempaka.2). Memberikan pelatihan kepada pengurus dan kader KKB tentang Teknis budidaya lele dan tanam kangkung hidroponik pada Bioflok; 3) Memberikan pelatihan pembuatan pakan bermikroba ; 4) Memperbaiki dan memanfaatkan bioflok yang ada sehingga dapat produktif kembali. Hasil PkM ini menunjukkan bahwa Kegiatan PkM Pendampingan berupa penyuluhan dan pelatihan teknis beternak lele bioflok dan kangkung hidroponik berlangsung dengan baik dan lancar. Peserta dapat memahami penjelasan mengenai teknis beternak lele bioflok dan kangkung hidroponik. Berdasarkan hasil evaluasi kegiatan, pengetahuan dan pemahaman peserta juga mengalami peningkatan. Pendampingan ini membantu kader Kampung KB Cempaka  dalam memanfaatkan potensi sekitar KKB untuk  beternak lele bioflok dan kangkung hidroponik
Efek Antiproliferatif Ekstrak dan Fraksi Daun Mahoni pada Sel Hela Diah Komala Sari; Nur Arifah; Gusti Ayu Widayanti
JPP JURNAL KESEHATAN POLTEKKES PALEMBANG Vol 20 No 2 (2025): JPP (Jurnal Kesehatan Poltekkes Palembang)
Publisher : Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jpp.v20i2.2920

Abstract

Background: Cervical cancer is one of the leading causes of death among women, particularly in developing countries. The development of anticancer agents from natural sources such as mahogany leaves (Swietenia mahagoni (L.) Jacq.) continues to attract research interest due to their promising potential. This study aimed to evaluate the antiproliferative effects of ethanol extract and bioactive fractions of mahogany leaves on cervical cancer (HeLa) cells in vitro. Methods: This research employed an experimental quantitative approach. Mahogany leaves were extracted using ethanol and further fractionated with n-hexane, ethyl acetate, and ethanol-water. Cell viability was assessed using the MTT assay and an ELISA reader at a wavelength of 550 nm. Antiproliferative activity was determined by measuring cell doubling time after treatment using ½ IC₅₀ concentration of the active fraction. The phytochemical constituents in the active fraction were identified through thin-layer chromatography (TLC). Results: The ethyl acetate fraction exhibited significant antiproliferative activity with a doubling time of 59 hours, compared to 34 hours in the control group and 81 hours with cisplatin. Absorbance values at 72 hours were also lower than the control, indicating suppressed cell proliferation. Phytochemical analysis identified the presence of flavonoids, saponins, and limonoids as major bioactive candidates. Conclusion: The ethyl acetate fraction of mahogany leaf extract demonstrates antiproliferative activity against HeLa cells and shows potential for development as a natural anticancer agent.
Co-Authors Atidira Dwi Hanani DIAH KOMALA SARI Gusti Ayu Widayanti Tien Yustini, Tien