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All Journal Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Jurnal Pengabdian Ilmu Kesehatan
Shinta Sari Dewi
Institut Kesehatan Mitra Bunda
Health Professions Medicine & Pharmacology Public Health

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PENETAPAN KADAR FENOLIK TOTAL DAN PENGUJIAN AKTIVITAS ANTIOKSIDAN EKSTRAK BRONOK (Acaudina molpadioides) : THE DETERMINATION OF TOTAL PHENOLIK CONTENT AND TESTING OF ANTIOXIDANT ACTIVITY OF BRONOK EXTRACT (Acaudina molpadioides) Suhaera; Shinta Sari Dewi; Umi Kalsum
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 3 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i3.387

Abstract

Indonesia merupakan salah satu kepulauan terbesar di dunia dengan dua pertiga wilayahnya adalah lautan, namun masih banyak biota laut yang belum bisa dimanfaatkan secara optimal, salah satu biota laut yang memiliki bioaktif adalah bronok (Acaudina molpadioides). Penelitian ini bertujuan untuk mengetahui kadar fenolik total dan aktivitas antioksidan pada ekstrak metanol, etil asetat dan n-heksan pada bronok (Acaudina molpadioides).Metode yang digunakan adalah metode FRAP (Ferric Reducing Antioxidant Power) dan penetapan kadar fenolik total. Hasil pengujian antioksidan pada ekstrak metanol, etil asetat, n-heksan memiliki nilai FRAP sebesar 79,531 mgAAE/g ekstrak, 60,859 mg AAE/g ekstrak dan 43,932 mg AAE/g ekstrak. Hasil pada fenolik total pada ekstak metanol sebesar 2,161 mg/g, ekstrak etil asetat sebesar 0,839 mg/g dan n-heksan sebesar 0,461 mg/g. Hasil tersebut menunjukkan ekstrak bronok dan fenolik total yang kuat sebagai antioksidan.
Gerakan Masyarakat Cerdas Menggunakan Obat ( GEMA CERMAT ) Di Kampung Baru Kecamatan Galang Delladari Mayefis; Reny Haryani; Shinta Sari Dewi; Sri Hainil; Andi Bunga Dahlia; Faziyana Faziyana; Merry Ardini; Selawati Selawati
Jurnal Pengabdian Ilmu Kesehatan Vol. 1 No. 2 (2021): Juli: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v1i2.3589

Abstract

There are still many problems with drug use among the public, including: Purchasing drugs not from licensed/official facilities, purchasing prescription drugs, purchasing antibiotics freely without a doctor's prescription, excessive use of over-the-counter drugs (over dosage), occurrence of side effects, drug interactions or misuse. Medicines often occur in society and can cause new health problems, there are still many people who do not understand how to store and dispose of medicines properly
Uji Senyawa Bioaktif Dan Toksisitas Limbah Cangkang Kerang Hijau (Pera Viridis) Suhaera Suhaera; Aprilya Sri Rachmayanti; Shinta Sari Dewi; St. Mursyidah; Dachriyanus Dachriyanus
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 1 No. 3 (2021): NOVEMBER : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v1i3.2932

Abstract

Green mussels are organisms belonging to the class pelecypoda, this class has two bilaterally symmetric valve shells, these green mussels are referred to as bivalves, and are included in the soft-bodied marine biota (Mollusca). This study aims to determine the bioactive compounds and toxicity contained in the shells of green mussels (Perna viridis) which are processed seafood typical of the Riau Islands. Secondary metabolite screening tests include alkaloids, flavonoids, tannins, saponins, steroids and terpenoids as for toxicity tests using the BSLT (Brine Shrimp Lethality Test) method with shrimp larvae (Artemia salina Leach) test animals. The results of secondary metabolite screening on the test for alkaloids, flavonoids, tannins, steroids and terpenoids were declared negative while the saponin test was positive with the formation of stable foam. The results of the BSLT toxicity test (Brine Shrimp Lethality Test) with concentrations of 10 ppm, 100 ppm, and 1000 ppm obtained LC50 <1000 g/ml, which is 1127.28 ppm in the non-toxic category. In the sense that it is safe to be used as processed food.
Uji Efek Stimulan Sistem Saraf Pusat Dari Ekstrak Etanol Biji Pala (Myristica fragrans H.) Pada Mencit Putih Jantan Delladari Mayefis; Shinta Sari Dewi; Nurlia Oktaviyanti; Arie Vonikartika
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 1 No. 2 (2021): JULI : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v1i2.2943

Abstract

Research on the effects of central nervous system stimulants from nutmeg (Myristica Fragrans H.) ethanol extract on male white mice has been carried out using the methods of: sleep onset test, hanging test, swimming test, and evacuation test. In this study, the test animals were divided into five groups in which each group consisted of three animals for three experiments, the first group was given a 0.5% NaC CMC suspention, the next three groups were given extracts of nutmeg seed ethanol (Myristica Fragrans H. ) with three variations of doses, namely 150, 300, and 600 mg / Kg BW, the next group as a comparison was given a caffeine solution of 13 mg / kg BW. Each preparation was given orally and then carried out a observation of several test methods. The results showed that the ethanol extract of nutmeg (Pala H.) can provide a good stimulant effect at a dose of 300 mg / kg BW (p <0.05) which was clearly seen in the swimming test and the hanging test method.
Co-Authors Andi Bunga Dahlia Aprilya Sri Rachmayanti Arie Vonikartika Dachriyanus Dachriyanus Delladari Mayefis Faziyana Faziyana Merry Ardini Nurlia Oktaviyanti Reny Haryani Selawati Selawati Sri Hainil St. Mursyidah Suhaera Suhaera Suhaera Umi Kalsum