Claim Missing Document
Check
Articles

Found 29 Documents
Search

Analysis of antioxidant activity of carrots (Daucus carrota L.) using FRAP and CUPRAC methods Aprilya Sri Rachmayanti; Nurmaya Effendi; Andi Muflihunna
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 6 No. 1 (2021)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v6i1.13981

Abstract

Carrot antioxidant activity analysis has been carried out. Carrot juice was analyzed qualitatively by the FRAP method using FRAP reagent and by the CUPRAC method using copper (II) chloride solution, neucuproine solution, ammonium acetate buffer solution, and distilled water. Quantitatively, the mixture of sample solutions using the FRAP and CUPRAC methods was analyzed using a UV-Vis spectrophotometer at a wavelength of 596 nm for the FRAP method and 452 nm for the CUPRAC method, using Trolox solution as the standard curve. The results obtained were that each sample A and B's antioxidant activity using the FRAP method was 0.5186 µM TR/g and 0.8857 µM TR/g samples. Meanwhile, samples A and B's antioxidant activity using the CUPRAC method was 0.1160 µM TR/g sample and 0.1762 µM TR/g sample.
Antibacterial Activity Test of Meniran Herb Extract (Phyllanthus Niruri L.) against Staphylococcus Epidermidis and Klebsiella Pneumoniae Nahrul Hasan Nahrul; Aprilya Sri Rachmayanti; Eem Masaenah
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.927

Abstract

An antibacterial test of meniran herb extract (Phyllanthus niruri L.) against Staphylococcus epidermidis and Klebsiella pneumoniae has been carried out. Meniran herb powder was screened for phytochemicals to assess the secondary metabolites contained in it, then meniran herbs were extracted using the soxhletation method in stages with various solvents (n-hexane, ethyl acetate, and 70% ethanol). The disc diffusion method was used to test the inhibition zone diameter of n-hexane extract, ethyl acetate extract, and ethanol extract against Staphylococcus epidermidis and Klebsiella pneumoniae. Meniran herb extract was diluted with a concentration series using dimethylsulfoxide. Meniran herb extracts from the three types showed the best inhibition zone diameter when tested for minimum inhibitory concentration (MIC) by the solid dilution method. The results showed that meniran herb powder contained flavonoids, saponins, tannins, glycosides, and steroids/terpenoids. Antibacterial tests showed that ethyl acetate and 70% ethanol extracts had antibacterial activity only against Staphylococcus epidermidis. The antibacterial activity of the two meniran herb extracts had the largest inhibition zone diameter against Staphylococcus epidermidis at a concentration of 50%, which was 12,33 mm for the ethyl acetate extract and 16,00 mm for the ethanol extract. The MIC test of the ethanol extract of the meniran herb, which had the best antibacterial activity, found that at a concentration of 2,5% it was able to inhibit the growth of Staphylococcus epidermidis.
Hubungan Karakteristik Penderita Hipertensi dengan Tingkat Kepatuhan Minum Obat di RSUD Embung Fatimah Kota Batam Suci Fitriani Sammulia; Aprilya Sri Rachmayanti; Erna Chintia
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 1 No. 3 (2022): Juli 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v1i3.429

Abstract

Hypertension is one of the non-communicable diseases which is a problem in the health sector and is often found in primary health services. A person is said to suffer from hypertension when systolic blood pressure ≥ 140 mmHg and diastolic pressure ≥ 90 mmHg. The use of antihypertensive drugs alone is proven to be insufficient to produce long-term blood pressure control effects if it is not supported by adherence to the use of antihypertension. The high incidence of hypertension in the world, is influenced by two types of factors, namely factors that cannot be changed such as age, sex, and race. Furthermore, factors that can be changed include obesity, alcohol consumption, lack of exercise, excessive salt consumption, and smoking habits. The purpose of this study was to determine the relationship between the characteristics of hypertension sufferers with the level of adherence to take medication at Embung Fatimah District Hospital in Batam. This study used a cross-sectional descriptive study method using the MMAS-8 (Morisky Medication Adherence Scale) questionnaire. Respondents who were the subject of this study were suffering from hypertension at Embung Fatimah Regional Hospital in Batam. The sampling technique used is a simple random sampling technique with a total sample of 96 people. The results of this study generally showed that 36.5% of patients had high adherence to take hypertension medication while the remaining 13.5% of patients had moderate adherence and as many as 50% had high adherence. To support the success rate of hypertension treatment can be done with the presence of hypertension counseling so that adherence to taking medication for hypertension sufferers can increase.
Aktivitas Antibakteri Ekstrak Bronok (Acaudina molpadioides) terhadap Pertumbuhan Bakteri Staphylococcus aureus dan Escherichia coli: Antibacterial Activity of Bronok Extract (Acaudina molpadioides) against the Growth of Staphylococcus aureus and Escherichia coli Bacteria Suhaera Suhaera; Aprilya Sri Rachmayanti; Nadya Aoliyaninda
Jurnal Surya Medika (JSM) Vol. 8 No. 3 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i3.3599

Abstract

Bronok (Acaudina molpadioides) is a type of marine biota of the phylum Echinoderms class Holothuroidea that can empirically increase stamina and have positive effects on health. One of the infectious diseases such as diarrhea is caused by Escherichia coli and Staphylococcus aureus bacteria which are still a major problem in public health and have the potential to cause death. Most of these bacteria have developed resistance to antibiotics This study aims to determine the antibacterial activity of extracts of bronchus (Acaudina molpadioides) against the growth of Staphylococcus aureus and Escherichia coli bacteria. In addition, this study uses the disc diffusion method with concentrations of 25%, 50% and 75% with the sample used is bronchoconstriction extract. The results of the bland zone diameter showed that methanol extract was able to inhibit the growth of Staphylococcus aureus bacteria with an average diameter of 4.1 mm, 5.3 mm, and 5.8 mm, ethyl acetate extract which is 4.7 mm, 6.2 mm, and 15.2 mm. Methanol extract showed resistance to Escherichia coli bacteria with an average diameter of 3.7 mm, 4.5mm, and 5 mm. The results of the bronok extract study (Acaudina molpadioides) had antibacterial activity against Staphylococcus aureus bacteria in methanol and ethyl acetate extracts. Methanol extract has antibacterial activity against Escherichia coli bacteria. By looking at the inhibition zone of each solvent where the larger the inhibition zone, the stronger the antibacterial activity.
Optimization of HPMC as Gelling Agent in Gel Formula of Etanol Extract of Bangun-Bangun Leaves (Plectranthus amboinicus (Lour) Spreng) Suci Fitriani Sammulia; Aprilya Sri Rachmayanti; Joel Lam Parulian Tampubolon
Jurnal EduHealth Vol. 14 No. 01 (2023): Jurnal eduHealth, Periode Januari-Maret, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (217.498 KB)

Abstract

Hidroxy Propyl Methyl Cellulose (HPMC) is a semi synthetic cellulose derivative gelling agent and can form a clear and neutral gel and has a stable viscosity in the long run. This study aims to determine the concentration of how much HPMC can form ethanol extracts of bangun-bangun leaves (Plectranthus amboinicus (Lour) Spreng) and stability of gel extract preparations. This research is an experimental study, in which the ethanol extract gel formulation of bangun-bangun leaves (Plectranthus amboinicus (Lour) Spreng) was conducted, by varying the concentration of HPMC at concentrations of 3%, 4% and 5%. Bangun-bangun leaves extract obtained from the maceration process and formulated in gel form. Furthermore, physical properties were evaluated, which included tests of adhesion, dispersion, pH, and viscosity on the bangun-bangun leaves extract gel. The evaluation results are then presented in tabular form. The evaluation results are then presented in tabular form. The optimum formula of the bangun-bangun leaves extract gel is a formula that contains 4% HPMC. Based on the results of the study is known that the results of the evaluation of the physical properties can be said to be stable after 4 weeks of stronge.
Antioxidant activity test of packaged juice variants of guava (psidium guajava L.) using FRAP (ferric reducing antioxidant power) method Aprilya Sri Rachmayanti; Nahrul Hasan; Suci Fitriani Sammulia; Henny Rachdiati; Yeni Febriyanti
Science Midwifery Vol 11 No 2 (2023): June: Midwifery and Health Sciences
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i2.1257

Abstract

Packaged juice are usually made using only one type of fruit or can be made using two types of fruits or other additional ingredients. Antioxidants are chemical compounds that can be used to protect biological components such as lipids, proteins, vitamins, and DNA. This study aims to determine the level of antioxidant activity in packaged juice drink variants of guava fruit using the FRAP (Ferric Reducing Antioxidant Power) method. The method used in this study is the FRAP method to test antioxidant activity. The results of testing the antioxidant activity with the FRAP (Ferric Reducing Antioxidant Power) method on the packaged juice drink samples, the level of antioxidant activity in juice drink sample A was 88,359 mgAAE/g sample, sample B was 88,202 mgAAE/g sample, sample C was 83,098 mgAAE/g sample, and sample D was 77,317 mgAAE/g sample. This shows that sample A demonstrated the highest antioxidant activity, followed closely by sample B, while samples C and D exhibited lower levels of antioxidant activity.
Gambaran Pelaksanaan Penyimpanan Cara Distribusi Obat Yang Baik Dan Benar (CDOB) Di PBF BUMN Dan Non BUMN Kota Batam Aprilya Sri Rachmayanti; Mawarni Badar; Chintia Wulandari; Suci Fitriani Sammulia; Reny Haryani; Nahrul Hasan
The Journal General Health and Pharmaceutical Sciences Research Vol. 1 No. 2 (2023): June: The Journal General Health and Pharmaceutical Sciences Research
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/tjghpsr.v1i2.186

Abstract

Good Distribution Method (CDOB) is a method of distributing or dispensing drugs and/or medicinal substances that aims to ensure quality by quality requirements and intended use in a distribution channel. Actions related to drug distribution are the acquisition, storage, and distribution of drugs from manufacturers to consumers. The use of CDOB is expected to maintain the quality of drugs received by patients and ensure conformity with the quality of drugs from the pharmaceutical industry. The research aims to find out the results of the implementation of Good Medicine Distribution Methods at PBF Enseval Putera Megatrading Tbk and PBF Kimia Farma Trading Distribution. This research is a type of observational research (evaluative non-experimental) that is descriptive in nature to get a realistic and objective picture of a condition that is currently occurring in a community group which contains questions addressed to Pharmaceutical Personnel on duty at PBF Kimia Farma and PBF Enseval Putera Megatrading Tbk Batam City. The results of research on PBF Enseval Putera Megatrading Tbk, and PBF Kimia Farma Trading Distribution, namely the score obtained from the evaluation results of CDOB implementation at PBF Enseval Putera Megatrading Tbk is in the very good category, namely with a percentage of (99%) and the score obtained from the evaluation results of CDOB implementation in PBF Kimia Farma Trading Distribution is in the very good category, namely with a percentage of (99%). Based on the research results, the description of CDOB implementation at PBF Enseval Putera Megatrading Tbk and Kimia Farma Trading Distribution is in the very good category (99%).
Analisis Waktu Tunggu Pelayanan Resep Non Racikan Pada Pasien Badan Penyelenggara Jaminan Sosial (BPJS) Di Rumah Sakit Harapan Bunda (RSHB) Kota Batam Nur Wafiq Azizah; Reny Haryani; Desy Maniarti Gusmali; Aprilya Sri Rachmayanti; Nahrul Hasan
An-Najat Vol. 1 No. 2 (2023): MEI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v1i2.965

Abstract

One of the Minimum Service Standards for hospital pharmacy is waiting time. Waiting time for drug service is the time from the patient submitting the prescription to receiving the drug. This study aims to analyze the accuracy of waiting time for non-recipe prescription services for BPJS patients at RSHB Pharmacy Batam City in accordance with Kepmenkes Number 129 / Menkes / SK / II / 2008 and determine the factors that cause the length of a prescription service process. This study used purposive sampling method for BPJS patients at RSHB Batam City. This research concludes with a sample size of 187 non-recipe prescriptions. The conclusion of this study is that the average prescription service time is 49.11 minutes, which means that the Batam City RSHB Pharmacy has not met the Minimum Hospital Service Standards
Pengabdian Kepada Masyarakat Melalui Penyuluhan Pemberian Makan Yang Tepat Pada Bayi Dan Dalam Upaya Pencegahan Stunting Di Bengkong Sadai Kota Batam Suhaera Suhaera; Aprilya Sri Rachmayanti; Yunisa Friscia Yusri; Ghalib Syukrillah Syahputra
ARDHI : Jurnal Pengabdian Dalam Negri Vol. 1 No. 1 (2023): ARDHI : Jurnal Pengabdian Dalam Negri
Publisher : Asosiasi Riset Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ardhi.v1i1.217

Abstract

The prevalence of stunting is one of the biggest nutritional problems among toddlers in Indonesia. The proportion of short and very short nutritional status in babies under two years old (baduta) reached 29.9% or higher than the 2019 RPJMN target, which was 28%. Stunting due to malnutrition that occurs in the First 1000 Days of Life (HPK) notonly causes obstacles to physical growth and increases vulnerability to disease, but also threatens cognitive development which will affect children's intelligence and productivity levels.Objective: To know the nutritional status of children under five, especially related to stunting, to increase parents' knowledge about stunting, to raise public awareness of the dangers of stunting.The activities consist of preparation stages, implementation of counseling which begins with filling in the pre-test questionnaire and ends with filling in the post-test questionnaire, as well as the evaluation stage.
Pengabdian Kepada Masyarakat Melalui Peningkatan Kualitas Hidup Lansia Melalui Penerapan Pola Hidup Sehat Di Batam Aprilya Sri Rachmayanti; Suhaera Suhaera; Ghalib Syukrillah Syahputra; Henny Rachdiati
ARDHI : Jurnal Pengabdian Dalam Negri Vol. 1 No. 1 (2023): ARDHI : Jurnal Pengabdian Dalam Negri
Publisher : Asosiasi Riset Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ardhi.v1i1.220

Abstract

The aging process is a natural phenomenon experienced by every individual, characterized by physical and mental changes that affect the body's functions and capabilities. The speed of the aging process can vary between individuals due to the influence of hormones and other factors. Elderly is often thought of as a disease, whereas aging is actually a natural process of decreasing the body's resistance to external and internal stimuli. During aging, the elderly experience physical, mental and psychological changes. Efforts to improve the health of older adults with chronic diseases are made through the adoption of a healthy lifestyle. This includes regular exercise programs, a healthy diet by limiting salt, fat, and cholesterol intake, quitting smoking, avoiding alcoholic beverages and caffeine, managing emotional stress, and undergoing regular monthly health check-ups. With age, older adults are at risk of various diseases, decreased body functions, imbalances, and the risk of falls. These challenges often conflict with older adults' desire to remain independent and active. The mismatch between expectations and conditions can even lead to depression. Therefore, there is a need for special attention to the health and well-being of the elderly with chronic diseases to maintain their quality of life.