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All Journal Borneo Journal Of Pharmascientech
Rabiatul Munawarah
Universitas Borneo Lestari
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Uji Aktivitas Antibakteri Fraksi N-Heksana Ekstrak Etanol 96% Daun Pare (Momordica charantia L.) Terhadap Bakteri Staphylococcus epidermidis Rabiatul Munawarah; Putri Kartika Sari; Eka Fitri Susiani
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.494

Abstract

Pare leaves (Momordica charantia L.) have many health benefits. Leaves pare (M.chrantia L.) are a trusted herb that is used as an antibacterial plant. N-hexane fraction of pare leaves(S. epidermidis). The purpose of this study is to identify the secondary metabolite compounds found in the n-hexane fraction of ethanol extract 96% of pare leaves (M.charantia L.) and to find out the N-hexane fractions of etanol 96% pare leaves (M.charantia L.) in inhibiting S.epidermidis bacteria. The type of research is experimental. The leaf extraction process uses maseration with 96% ethanol solvent and fraxination using n-hexane solvent. Phytochemical screening tests include flavonoids, alkaloids, saponins, steroids/terpenoids, phenols and tannins. The antibacterial activity carried out using well method with concentration of 1%, 2%, 3% and 4%. The results of this study showed that a fraction of n-hexane ethanol extract 96% of the leaf (M.charantia L.) contained flavonoid, alkaloid and steroid compounds. The n-hexane fraction ethanol extract 96% leaf (M.charantia L.) has antibacterial activity in inhibiting the S.epidermidis bacteria in the weak to strong category. Based on the results, it can be concluded that the fraction n-hexane ethanol extract 96% of the leaf (Momordica charantia L.) is able to inhibit the bacteria S.epidermidis at all concentrations.
Co-Authors Eka Fitri Susiani Putri Kartika Sari