Article Per Year (5 Year)
p-Index From 2020 - 2025
0.751
P-Index
This Author published in this journals
All Journal Borneo Journal Of Pharmascientech Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Eka Fitri Susiani
Universitas Borneo Lestari
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Penentuan Parameter Nonspesifik Ekstrak Etanol Kulit Batang Tandui (Mangifera rufocostata Kosterm.) Indah Widya Lestari; Revita Saputri; Rahmi Muthia; Eka Fitri Susiani
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 1 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i1.449

Abstract

The cortex of tandui has the potential to be a folk remedy. As an ingredient in traditional medicine, it is necessary to characterize the cortex of tandui as a first step in knowing the quality of the quality of the extract in accordance with the established extract monograph, namely with nonspecific parameters. This study aims to determine the results of the characterization value of nonspecific parameters of ethanol extract of cortex tandui (Mangifera rufocostata Kosterm.). In this study, the extraction of the cortex tandui used the maceration method with a 70% ethanol solvent with a yield gain of 21.1%. The determination of nonspecific parameters includes type weight, moisture content, ash content, acid insoluble ash content, heavy metal contamination, yeast mold contamination and microbial contamination. Ethanol extract of the cortex tandui (Mangifera rufocostata Kosterm.) has successive nonspecific parameter characterization values, namely, type weight of 1.11 grams, moisture content of 42.73%, ash content of 2.28%, acid insoluble ash content of 0.035%, lead metal contamination (Pb) <0.001 mg/kg, cadmium metal contamination (Cd) < 0.001 mg/kg, yeast mold contamination 1,2 × colonies/g and microbial contamination < 1,0 × colonies/g. From the above results, it can be implied that the determination of nonspecific parameters of the ethanol extract of the cortex tandui (Mangifera rufocostata Kosterm.) meets the requirements set except for the parameters of moisture content that exceeds the requirements.
Aktivitas Antioksidan Ekstrak Metanol Daun Tandui (Mangifera rufocostata K.)Menggunakan Metode DPPH Eka Fitri Susiani; Revita Saputri; Helmina Wati; Fitria Mahmudah; Vebruati Vebruati
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.477

Abstract

Free radicals are highly reactive compounds because they have unpaired electrons so that they can interact with body cell molecules, this can cause various diseases. Antioxidants are compounds that can ward off free radicals. Plants of the genus Mangifera are known to have antioxidant activity, one of which is Mangifera rufocostata Kosterm, a typical plant of South Kalimantan known as tandui. The purpose of this study was to determine the antioxidant activity of the methanol extract of the leaves of tandui (Mangifera rufocostata Kosterm.) using the DPPH test method. Phytochemical screening and antioxidant activity tests were performed using a UV-Vis spectrophotometer. The compounds contained in the methanol extract of tandui leaves (Mangifera rufocostata Kosterm.) are phenols, flavonoids, and tannins. The IC50 value of quercetin obtained was 2.39 ppm and the IC50 value of the tandui leaf methanol extract (Mangifera rufocostata Kosterm.) which was obtained was 8.222 ppm. Tandui leaf methanol extract has very strong antioxidant activity.
Uji Aktivitas Antibakteri Fraksi N-Heksana Ekstrak Etanol 96% Daun Pare (Momordica charantia L.) Terhadap Bakteri Staphylococcus epidermidis Rabiatul Munawarah; Putri Kartika Sari; Eka Fitri Susiani
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.494

Abstract

Pare leaves (Momordica charantia L.) have many health benefits. Leaves pare (M.chrantia L.) are a trusted herb that is used as an antibacterial plant. N-hexane fraction of pare leaves(S. epidermidis). The purpose of this study is to identify the secondary metabolite compounds found in the n-hexane fraction of ethanol extract 96% of pare leaves (M.charantia L.) and to find out the N-hexane fractions of etanol 96% pare leaves (M.charantia L.) in inhibiting S.epidermidis bacteria. The type of research is experimental. The leaf extraction process uses maseration with 96% ethanol solvent and fraxination using n-hexane solvent. Phytochemical screening tests include flavonoids, alkaloids, saponins, steroids/terpenoids, phenols and tannins. The antibacterial activity carried out using well method with concentration of 1%, 2%, 3% and 4%. The results of this study showed that a fraction of n-hexane ethanol extract 96% of the leaf (M.charantia L.) contained flavonoid, alkaloid and steroid compounds. The n-hexane fraction ethanol extract 96% leaf (M.charantia L.) has antibacterial activity in inhibiting the S.epidermidis bacteria in the weak to strong category. Based on the results, it can be concluded that the fraction n-hexane ethanol extract 96% of the leaf (Momordica charantia L.) is able to inhibit the bacteria S.epidermidis at all concentrations.
PENETAPAN KADAR TOTAL FENOLIK-FLAVONOID EKSTRAK ETANOL 70% KULIT BATANG TANDUI (Mangifera rufocostata Kosterm.) Eka Fitri Susiani; Revita Saputri; Allisa Fanadia; Liana Fitriani Hasymi
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.676

Abstract

Tandui (Mangifera rufocostata Kosterm.) is a species of the genus Mangifera which is known to contain phenolic and flavonoid compounds and is one of the plants used as an alternative medicine by the people of South Kalimantan. The purpose of this study was to determine the total phenolic and flavonoid content of 70% ethanol extract of tandui bark. Qualitative analysis using phenolic and flavonoid phytochemical screening with 3% FeCl3, Mg-HCl reagents and Thin Layer Chromatography (TLC) with spot appearance 10% FeCl3 for phenolic and 5% AlCl3 for flavonoid compounds. Quantitative analysis using UV-Vis spectrophotometry, determination of total phenolic content using Folin-Ciocalteu reagent with gallic acid standard solution, while determination of total flavonoid content using AlCl3 reagent with quercetin standard solution. The results of identification of phenolic and flavonoid compounds by phytochemical screening and TLC showed that 70% ethanol extract of tandui bark contained phenolic and flavonoid. The results of the determination of the total phenolic content using UV-Vis spectrophotometry were 471.3126 mgGAE/g or 47.1312%, while the total flavonoid content was 872.075 mgQE/g extract or 87.2075%. Based on these results, it can be concluded that 70% ethanol extract of tandui bark contains secondary metabolites in the form of phenolics and flavonoids which have potential as medicine.
Co-Authors Allisa Fanadia Fitria Mahmudah Helmina Wati Indah Widya Lestari Liana Fitriani Hasymi Putri Kartika Sari Rabiatul Munawarah Rahmi Muthia Saputri, Revita Vebruati Vebruati