Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal Jurnal Ilmiah Farmako Bahari Jurnal Farmasi dan Farmakoinformatika
Tsurayya, Nadya
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
ANTIBACTERIAL ACTIVITY OF BACANG MANGO (Mangifera foetida L.) LEAVES ETHANOL EXTRACT IN GEL FORMULATION AS ANTI-ACNE Aditya, Aditya; Jannati, Zahra Shaumi Jasmin; Hartianty, Eka Pebi; Tsurayya, Nadya
Jurnal Ilmiah Farmako Bahari Vol 15, No 2 (2024): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v15i2.3071

Abstract

Acne was a chronic skin disorder that was most often found in adolescents, so it frequently caused psychological effects that made the acne fighters look for ways to treat it quickly. Although topical antibiotics effectively treat acne, excessive long-term use can cause resistance. This has led to an interest in natural antimicrobials as an alternative treatment for acne. The natural antibacterial activity of the ethanol extract of bacang mango (Mangifera foetida L.) leaves has previously been reported to have antibacterial effects against Propionibacterium acnes, but only in the form of extracts not formulated into pharmaceutical preparations. Therefore, this study aimed to re-test the antibacterial activity of this extract, which has now been formulated into a gel preparation against the same bacteria. The gelling agent used in the gel formulation was Na-CMC with three different concentrations: 3%, 4%, and 5%. The Agar stab technique tests the antibacterial activity for three different extract concentrations. Those were 10%, 15%, and 20% for optimization of inhibitory activity before being formulated. Based on the results of testing the antibacterial activity of the ethanol extract of bacang mango (Mangifera foetida L.) leaves, an extract concentration of 20% had a more potent inhibitory activity than the others so that this concentration was chosen to be formulated into a gel preparation. After the formulation of the extracted gel, Na-CMC with a concentration of 5% produced a better gel base than other formulations. In addition, the three formulations provided the same inhibitory activity of 10 mm, so it can be concluded that the differences in gelling agent concentrations did not affect the antibacterial activity of the extracts in the preparations. However, a 3 mm decrease in inhibition occurred in the extract after it was formulated into a gel preparation. Even so, the extract gel preparation still has antibacterial activity against Propionibacterium acnes with antimicrobial inhibition zone activity, which is in the moderate category.
Formulation And Determination Of The SPF Value Of Sunscreen Cream Spirulina platensis Microalgae Extract Ramdhiany, Nova Azizah; Tsurayya, Nadya
Jurnal Farmasi dan Farmakoinformatika Vol 3, No 1 (2025)
Publisher : Universitas Gunadarma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35760/jff.2025.v3i1.12640

Abstract

Paparan sinar ultraviolet (UV) dari matahari yang berlebihan akan meningkatkan produksi Reactive Oxygen Species (ROS) dan mengaktifkan makrofag untuk melepaskan enzim matriks metalloproteinase (MMP) yang terlibat dalam degradasi matriks ekstraseluler kulit, seperti pelepasan kolagen dan elastin. Dalam mengatasi hal tersebut, lapisan epidermis kulit menyediakan berbagai senyawa penyerap sinar UV salah satunya yaitu melanin. Tetapi produksi pigmen melanin yang berlebihan dapat menyebabkan hiperpigmentasi yang menyebabkan tanda-tanda penuaan kulit. Sehingga, untuk mencegah hiperpigmentasi diperlukan tabir surya. Mikroalga Spirulina platensis menjadi salah satu bahan alam yang berpotensi sebagai bahan aktif tabir surya karena mengandung flavonoid dan senyawa fenolik yang melimpah. Kandungan tersebut bermanfaat untuk menyerap sinar UV. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi ekstrak etanol 90% Spirulina platensis yaitu 6%, 7%, dan 8% terhadap nilai SPF krim tabir surya dengan krim yang tidak diberi ekstrak, karakteristik fisik dan stabilitas sediaan krim tabir surya. Hasil pengujian SPF tertinggi secara in vitro dari krim dengan konsentrasi ekstrak 8% yaitu sebesar 22,05 dengan kategori proteksi ultra, dan krim yang tidak diberi ekstrak nilai SPFnya sebesar 0,5. Hasil evaluasi krim tabir surya berekstrak yaitu berwarna hijau pekat kecoklatan, bau khas wangi spirulina kuat, konsistensinya lembut, homogen, pH 6, tipe emulsi M/A, daya lekat 2-7 detik, dan daya sebar 5 – 6 cm. Uji stabilitas dengan cycling test menunjukkan hasil semua krim tabir surya stabil.
ANTIBACTERIAL ACTIVITY OF BACANG MANGO (Mangifera foetida L.) LEAVES ETHANOL EXTRACT IN GEL FORMULATION AS ANTI-ACNE Aditya, Aditya; Jannati, Zahra Shaumi Jasmin; Hartianty, Eka Pebi; Tsurayya, Nadya
Jurnal Ilmiah Farmako Bahari Vol 15 No 2 (2024): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v15i2.3071

Abstract

Acne was a chronic skin disorder that was most often found in adolescents, so it frequently caused psychological effects that made the acne fighters look for ways to treat it quickly. Although topical antibiotics effectively treat acne, excessive long-term use can cause resistance. This has led to an interest in natural antimicrobials as an alternative treatment for acne. The natural antibacterial activity of the ethanol extract of bacang mango (Mangifera foetida L.) leaves has previously been reported to have antibacterial effects against Propionibacterium acnes, but only in the form of extracts not formulated into pharmaceutical preparations. Therefore, this study aimed to re-test the antibacterial activity of this extract, which has now been formulated into a gel preparation against the same bacteria. The gelling agent used in the gel formulation was Na-CMC with three different concentrations: 3%, 4%, and 5%. The Agar stab technique tests the antibacterial activity for three different extract concentrations. Those were 10%, 15%, and 20% for optimization of inhibitory activity before being formulated. Based on the results of testing the antibacterial activity of the ethanol extract of bacang mango (Mangifera foetida L.) leaves, an extract concentration of 20% had a more potent inhibitory activity than the others so that this concentration was chosen to be formulated into a gel preparation. After the formulation of the extracted gel, Na-CMC with a concentration of 5% produced a better gel base than other formulations. In addition, the three formulations provided the same inhibitory activity of 10 mm, so it can be concluded that the differences in gelling agent concentrations did not affect the antibacterial activity of the extracts in the preparations. However, a 3 mm decrease in inhibition occurred in the extract after it was formulated into a gel preparation. Even so, the extract gel preparation still has antibacterial activity against Propionibacterium acnes with antimicrobial inhibition zone activity, which is in the moderate category.
Co-Authors Aditya Aditya Hartianty, Eka Pebi Jannati, Zahra Shaumi Jasmin Ramdhiany, Nova Azizah