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All Journal Pharmasipha JURNAL ILMIAH AGRINECA Applied Science and Technology Research Journal
A Hi Wahid, Rahmat
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Electrical & Electronics Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Description Of Antihypertensive Drugs Use In Hypertensive Outpatients With Diabetes Mellitus At Panembahan Senopati Bantul Hospital A Hi Wahid, Rahmat; Febri Nilansari, Anis; Andriani Fatimah, Fitri
APPLIED SCIENCE AND TECHNOLOGY REASERCH JOURNAL Vol. 3 No. 1 (2024): Applied Science and Technology Research Journal
Publisher : Lembaga Penelitian dan Pengabdian Mayarakat (LPPM) Universitas PGRI Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31316/astro.v3i1.6143

Abstract

Hypertension (HT) is still a health problem in the world, including in Indonesia. Hypertension in patients with type 2 diabetes mellitus (T2DM) will have an impact on worsening conditions and multi-complications, including macrovascular, microvascular, and insulin resistance complications. This can be prevented by providing appropriate and rational therapy so that the effectiveness of therapy is achieved and avoid worsening conditions and complications. This study aims to determine the pattern of antihypertensive drug use in HT patients with comorbid T2DM in the outpatient installation of Panembahan Senopati Hospital, Bantul for the period of August 2023. The study was designed with a descriptive non-experimental method, cross-sectional with a retrospective approach. The source of research data is secondary data derived from medical records of HT patients with T2DM for the period of August 2023 with data collection by purposive sampling. A total of 157 HT patients met the inclusion criteria in this study with the prevalence of women (n = 106; 67.50%) and men (n = 51; 32.50%), most ages in the 55-65 year range (n = 57; 36.30%). A total of 66 patients (42.10%) received monotherapy, while 91 (57.90) patients received polytherapy. Candesartan (n=80; 27.68%) and Amlodipine (n=78; 26.99%) monotherapy with oral administration were the most common treatment options in this study. Overall, the most widely used drug classes were Angiotensin Receptor Blockers (ARB) (41.18%), Calcium Channel Blockers (CCB) (32.5%), and Diuretics (14.1%). While the most common combination of drug groups is ARB + CCB (24.8%). This study concluded that the use of drugs mainly was polytherapy and in general the use of antihypertensive drugs consisted of 7 classes of drugs namely Angiotensin Receptor Blockers, Calcium Channel Blockers, Diuretics, ẞ- blockers, Centrally-acting Agents, ACE-Inhibitors, Vasodilators
Identifikasi Bakteri Endofit Dalam Penerapan Eco-Enzyme Pada Budidaya Jahe Merah (Zingiber Officinale Var. Rubrum) Bintang Pamungkas, Puguh; Purwaningsih, Okti; A Hi Wahid, Rahmat
JURNAL ILMIAH AGRINECA Vol 25 No 1 (2025): JURNAL ILMIAH AGRINECA
Publisher : Fakultas Pertanian, Universitas Tunas Pembangunan Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36728/afp.v25i1.4365

Abstract

During the COVID-19 pandemic, the use of red ginger as a herbal treatment increased significantly, establishing it as a highly popular herbal commodity. However, disruptions caused by plant pests have led to fluctuating demand. One major issue is bacterial wilt disease caused by Ralstonia solanacearum, which can result in yield losses of up to 90%. Biological control using endophytic bacteria has shown promise in managing bacterial wilt, particularly bacteria residing in the red ginger rhizosphere. This research aimed to explore and identify endophytic bacteria from the rhizosphere of red ginger plants. The study was conducted from September to October 2022 at the Greenhouse and Integrated Chemistry and Biology Laboratory, PGRI University Yogyakarta. Soil samples were collected from red ginger cultivation systems implementing eco-enzymes as part of a healthy farming approach. Four treatments were applied with three replications: no eco-enzyme, 0.1% eco-enzyme, 0.3% eco-enzyme, and 0.5% eco-enzyme. Each treatment involved three soil samplings, yielding a total of 36 soil samples for analysis. Exploration of the rhizosphere resulted in the isolation of 36 bacterial strains, of which 20 were identified as belonging to the genera Bacillus sp. and Pasteuria sp. Among these, 16 isolates were identified as Bacillus sp., including six from the no eco-enzyme treatment, one from the 0.3% eco-enzyme treatment, and nine from the 0.5% eco-enzyme treatment. Additionally, five isolates were identified as Pasteuria sp., with two from the 0.1% eco-enzyme treatment and three from the 0.3% eco-enzyme treatment.
Tingkat pengetahuan, persepsi, dan sikap konsumen terhadap kehalalan obat di Apotek UNISIA 24 Taman Sari Yogyakarta Sahlia, Siti Afifah; A Hi Wahid, Rahmat
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 9 No. 1 (2025): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v9i1.10590

Abstract

Indonesia is one of the countries with the largest Muslim population in the world. So that public awareness and knowledge related to halal product guarantees is very important, one of which is the guarantee on pharmaceutical products. The purpose of this study was to determine the high level of knowledge, perceptions, and attitudes of consumers at the UNISIA 24 Taman Sari Yogyakarta Pharmacy. The research was conducted from March to May 2023. This research is a descriptive observational type. The data collection instrument uses a questionnaire and the data results are processed using statistical analysis applications. The results showed, at the level of knowledge it was known that 53% were categorized as good, 45% were categorized as sufficient and 2% were categorized as deficient. In perception, it is known that 92% are categorized as good and 9% are categorized as sufficient, in attitude it is known that 87% of respondents are categorized as good and 13% are categorized as sufficient. Based on this, it can be concluded that the average value of the level of knowledge (77%), perception (83%) and consumer attitudes (84%) towards the halalness of drugs at the UNISIA 24 Taman Sari Yogyakarta Pharmacy is in the good category.
Description Of Antihypertensive Drugs Use In Hypertensive Outpatients With Diabetes Mellitus At Panembahan Senopati Bantul Hospital A Hi Wahid, Rahmat; Febri Nilansari, Anis; Andriani Fatimah, Fitri
APPLIED SCIENCE AND TECHNOLOGY REASERCH JOURNAL Vol. 3 No. 1 (2024): Applied Science and Technology Research Journal
Publisher : Lembaga Penelitian dan Pengabdian Mayarakat (LPPM) Universitas PGRI Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31316/astro.v3i1.6143

Abstract

Hypertension (HT) is still a health problem in the world, including in Indonesia. Hypertension in patients with type 2 diabetes mellitus (T2DM) will have an impact on worsening conditions and multi-complications, including macrovascular, microvascular, and insulin resistance complications. This can be prevented by providing appropriate and rational therapy so that the effectiveness of therapy is achieved and avoid worsening conditions and complications. This study aims to determine the pattern of antihypertensive drug use in HT patients with comorbid T2DM in the outpatient installation of Panembahan Senopati Hospital, Bantul for the period of August 2023. The study was designed with a descriptive non-experimental method, cross-sectional with a retrospective approach. The source of research data is secondary data derived from medical records of HT patients with T2DM for the period of August 2023 with data collection by purposive sampling. A total of 157 HT patients met the inclusion criteria in this study with the prevalence of women (n = 106; 67.50%) and men (n = 51; 32.50%), most ages in the 55-65 year range (n = 57; 36.30%). A total of 66 patients (42.10%) received monotherapy, while 91 (57.90) patients received polytherapy. Candesartan (n=80; 27.68%) and Amlodipine (n=78; 26.99%) monotherapy with oral administration were the most common treatment options in this study. Overall, the most widely used drug classes were Angiotensin Receptor Blockers (ARB) (41.18%), Calcium Channel Blockers (CCB) (32.5%), and Diuretics (14.1%). While the most common combination of drug groups is ARB + CCB (24.8%). This study concluded that the use of drugs mainly was polytherapy and in general the use of antihypertensive drugs consisted of 7 classes of drugs namely Angiotensin Receptor Blockers, Calcium Channel Blockers, Diuretics, ẞ- blockers, Centrally-acting Agents, ACE-Inhibitors, Vasodilators
Co-Authors Bintang Pamungkas, Puguh Fitri Andriani Fatimah Nilansari, Anis Febri OKTI PURWANINGSIH Sahlia, Siti Afifah