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All Journal Jurnal Ilmiah Kesehatan Masyarakat Jurnal Pengabdian Ilmu Kesehatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Habibie Deswilyaz Ghiffari
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Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi

 1 
Optimasi Dan Formulasi Sediaan Gel Ekstrak Etanol Hydrocotyle Verticillata Thub Dengan Variasi Konsentrasi HPMC Dengan Penambahan Asam Usnat Habibie Deswilyaz Ghiffari; Alqushay Alqushay; Sri Budiasih; Tommy Julianto
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 1 (2024): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i1.155

Abstract

Hydrocotyle verticillata Thub is a plant that can be used to treat burns. Usnic acid can inhibit pathogenic microorganisms and can act as an anti-inflammatory, both of which can contribute to the wound healing process. The aim of this research is to determine the extract of gotu kola leaves which is formulated into a gel preparation. Gel is a semi-solid system produced by small particles or large organic molecules that penetrate through a liquid. The gel is easy to use, easily absorbed into the skin, and contains soothing and moisturizing properties that have a healing effect. Gel formulations were made with varying concentrations of HPMC F1 (8%), F2 (8%), F3 (8%), F4 (9%), F5 (10%). The gel produced organoleptically has a distinctive gel aroma, green to brownish in color. In the homogeneity test, all preparations were homogeneous and there were no granules, the pH test showed a pH value ranging from 5.17-6.36, the spreadability test was 5.1-6.4 cm. In the viscosity test, the results were 9,250-40,000 cps, the adhesion test obtained results in 13-64 seconds and the cycling test was stable during storage. Based on the research that has been carried out, it can be concluded that the ethanol extract of gotu kola leaves (Hydrocotyle verticillata Thub)can be formulated into a gel preparation and the results of the physical evaluation of the ethanol extract gel preparation of gotu kola leaves(Hydrocotyle verticillata Thub) with varying concentrations of HPMC and the addition of usnic acid are satisfactory. condition.
Formulasi dan Evaluasi Sediaan Masker Gel Peel-Off Ekstrak Etanol Daun Jambu Bol (Syzygium malaccence (L.) Merr. & Perry) untuk Perawatan Kulit Wajah Sri Hainil; Sri Budiasih; Habibie Deswilyaz Ghiffari; Senny Mey Pratiwi; Desy Maniarti Gusmali
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 1 (2025): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i1.493

Abstract

The guava plant, also known as Syzygium malaccense (L.) Merr. & Perry, is a member of the Myrtaceae family and is rich in antioxidants. The therapeutic properties of this plant have been known for centuries. When compared to other sections of the guava plant, the leaves have the largest concentration of flavonoids. The purpose of this research is to develop and assess the physical characteristics of five different formulations of a peel-off gel mask containing guava leaf extract (Syzygium malaccense (L.)) at concentrations of 0% (F0), 2% (F1), 4% (F2), 8% (F3), and 12% (F5). The recipe was found to be consistent in appearance, smell, and taste throughout the organoleptic testing. The results of tests on pH, spreadability, and viscosity were statistically different (p0.05). Results from 4°C viscosity tests showed a range of 3933-7167 Cps. pH values ranged from 5.08 to 6.48 and spreadability from 5.23 to 6.50 cm when tested at 4, 25, and 40 degrees Celsius, respectively. The drying time test at 25°C and 40°C revealed no significant variations (p>0.05), and the viscosity test yielded values between 4100 and 4933 Cps at both temperatures. Ten test subjects were not irritated by any of the tested formulations. Finally, F4 (0.8%) showed the finest physical quality when incorporated into a guava leaf extract peel-off gel mask.
Co-Authors Alqushay Alqushay Amelia, Ayu Arie Vonikartika Delladari Mayefis Desy Maniarti Gusmali Gina Fernanda Komang Natalia Fitriani Lupina Lupina RENI NOVIANTI Senny Mey Pratiwi Sri Budiasih Sri Hainil Suci Fitriani Sammulia Tommy Julianto Yunisa Friscia Yusri