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All Journal E-Jurnal Medika Udayana International Journal of Public Health Excellence (IJPHE)
Mardaningrat, Kadek Herdana Vildan
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Health Professions Medicine & Pharmacology Nursing Public Health

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UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BUNGA KAMBOJA PUTIH (Plumeria alba) TERHADAP Streptococcus pyogenes Mardaningrat, Kadek Herdana Vildan; Aman, IGM; Jawi, I Made; Indrayani, Agung Wiwiek
E-Jurnal Medika Udayana Vol 12 No 4 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i04.P13

Abstract

ABSTRAK Streptococcus pyogenes merupakan bakteri gram positif berbentuk kokus yang sering menyebabkan infeksi pada saluran pernapasan manusia. Pertumbuhan Streptococcus pyogenes dapat dihambat oleh senyawa fitokimia yang berasal dari bahan alam seperti bunga kamboja putih (Plumeria alba). Ekstrak etanol bunga kamboja putih telah diketahui memiliki berbagai jenis senyawa fitokimia yang dapat berperan sebagai agen antibakteri. Tujuan dari penelitian ini adalah untuk menganalisis daya hambat ekstrak bunga kamboja putih pada konsentrasi 25%, 50%, 75%, dan 100% terhadap bakteri Streptococcus pyogenes. Penelitian in vitro ini menggunakan metode true experimental post-test only control group. Sampel penelitian dibagi menjadi enam kelompok, yaitu dua kelompok kontrol terdiri dari kontrol positif yang diberikan klindamisin dan kontrol negatif yang diberikan aquades, serta empat kelompok perlakuan yaitu konsentrasi 25%, 50%, 75%, dan 100%. Metode difusi agar (Kirby-bauer) digunakan sebagai uji antibakteri. Data hasil penelitian dianalisis menggunakan software SPSS. Hasil penelitian menunjukkan ekstrak bunga kamboja putih pada konsentrasi 25%, 50%, 75%, dan 100% mempunyai daya hambat terhadap Streptococcus pyogenes dengan diameter zona hambat sebesar 7.2 mm, 8.8 mm, 9.4 mm, dan 9.6 mm. Kontrol positif yang digunakan adalah klindamisin dengan diameter 38.8 mm. Analisis Kruskal-Wallis menunjukkan hasil 0.000 yang menandakan adanya perbedaan rata-rata luas zona hambat antar kelompok yang signifikan. Dengan demikian, ekstrak etanol bunga kamboja putih pada konsentrasi 25%, 50%, 75%, dan 100% berpotensi dalam menghambat pertumbuhan bakteri Streptococcus pyogenes. Kata kunci: Uji daya hambat, ekstrak, Plumeria alba, Streptococcus pyogenes
Medication Adherence and Physical Activity in Relation to Blood Pressure in Hypertension Patients Mahendra Mardaningrat, Gede Ari; Wiguna, Putu Dony Astika; Lestari, I Dewa Ayu Made Dian; Gayatri, Dewa Ayu Agung Maya; Mardaningrat, Kadek Herdana Vildan; Krisnanda, Made Yogi
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 1 (2023): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i1.651

Abstract

In the 21st century, it is estimated that there will be a rapid increase in the incidence and prevalence of NCDs. It is estimated that the countries that will feel the impact the most are developing countries, including Indonesia. One of the NCDs that is currently a very serious health problem is hypertension. This study aims to determine the relationship between medication adherence and physical activity on blood pressure in hypertension patients. This research is an analytical study with a cross-sectional design. Data collection was carried out by conducting interviews with patients, filling out questionnaires by the patient, viewing the patient's medical record data and carrying out blood pressure checks in September 2023 to October 2023. Bivariate analysis showed that there was an influence of medication attendance (p value = 0.0001; PR = 7.667) and physical activity (p value = 0.0001; PR = 26.156) on blood pressure. Multivariate analysis showed that physical activity (p value = 0.0001; aPR = 23.726) had more influence on blood pressure than medication adherence (p value = 0.007; aPR = 6.622). It is important for health workers to always educate patients regarding medication compliance and increase physical activity in an effort to achieve normal blood pressure.
Co-Authors Agung Wiwiek Indrayani Aman, IGM Gayatri, Dewa Ayu Agung Maya I Made Jawi Krisnanda, Made Yogi Lestari, I Dewa Ayu Made Dian Mahendra Mardaningrat, Gede Ari Wiguna, Putu Dony Astika