Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal Journal of Economic, Bussines and Accounting (COSTING) Indonesian Journal of Medical Chemistry and Bioinformatics
Abidin, Raniindra Khalisha Soediro
Unknown Affiliation
Chemistry Computer Science & IT Economics, Econometrics & Finance

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Phytochemical Screening, Antioxidant Activity, and Cytotoxicity of Ethanol, Ethyl Acetate, and n-Hexane Kluwak (Pangium edule) Extract on MCF-7 Breast Cancer Cells Abidin, Raniindra Khalisha Soediro; Arsianti, Ade
Indonesian Journal of Medical Chemistry and Bioinformatics Vol. 2, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Breast cancer occurs quite high and is one of the main causes of death in Indonesia and the world. Current treatment for cancer is expensive and has varying degrees of success and can cause side effects for patients. Kluwak (Pangium edule), whose reseach is still limited has the potential to be used as an alternative treatment for breast cancer. Methods: Kluwak powder was macerated using three different types of solvents to obtain ethanol extract, ethyl acetate extract and n-hexane kluwak extract. Phytochemical tests and thin layer chromatography (TLC) were carried out to determine the type and amount of phytochemical components of kluwak extract. The antioxidant activity of kluwak extract was tested using the DPPH method and the cytotoxic effect on MCF-7 breast cancer cells was determined using the MTT test. Results: The phytochemical components contained in kluwak extract include flavonoids, alkaloids, triterpenoids and glycosides. The ethanol extract of kluwak showed very weak antioxidant activity (IC50 = 26459 µg/ml), while the antioxidant activity of the ethyl acetate and n-hexane extracts could not be determined. Ethyl acetate and n-hexane kluwak extracts also had a moderate cytotoxic effect on MCF-7 breast cancer cells with IC50 values respectively 132.79 µg/ml and 232.93 µg/ml while the ethanol extract had a weak cytotoxic effect with values IC50 667.91 µg/ml.Conclusion: Kluwak (Pangium edule) extract contains phytochemical compounds and cytotoxic effects on MCF-7 breast cancer cells, so it has the potential to be developed as a therapeutic agent in the management of breast cancer.
KORELASI PENGGUNAAN REKAM MEDIS ELEKTRONIK TERHADAP KEPUASAN TENAGA KESEHATAN DI UNIT RAWAT JALAN RUMAH SAKIT PERMATA KELUARGA CABANG KARAWANG Permana, Noah Jefferson; Abidin, Raniindra Khalisha Soediro; Talia, Ani
Journal of Economic, Bussines and Accounting (COSTING) Vol 7 No 6 (2024): COSTING : Journal of Economic, Bussines and Accounting
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/costing.v7i6.13394

Abstract

Latar Belakang: Rekam Medis Elektronik (RME) yang ditujukan untuk peningkatan efektivitas kinerja tenaga kesehatan berpotensi mengalami tantangan dalam hal implementasinya karena ketidaksesuaian efektivitas kerja dan tingkat adaptabilitas. Hal ini dapat berpengaruh terhadap kinerja tenaga kesehatan. Kepuasan pengguna terhadap rekam medis elektronik merupakan salah satu indikator kinerja tenaga kesehatan dalam hal implementasi sistem informasi kesehatan. Tujuan: mengetahui tingkat korelasi tingkat kepuasan tenaga kesehatan terhadap implementasi RME di RS Permata Keluarga cabang Karawang. Metode: Studi ini menerapkan jenis penelitian deskriptif kuantitatif melalui pendekatan cross-sectional dan uji statistik chi-square. Hasil: Berdasarkan hasil analisis data sejumlah 75% responden memiliki tingkat kepuasan baik, sedangkan 25% memiliki kepuasan yang kurang baik yang dirincikan sebagai berikut, yaitu 66.7% menggunakan RME dengan kualitas yang kurang baik, dan 33.3% yang kepuasannya rendah tetap menggunakan RME dengan baik. Uji analisis statistik chi-square menunjukkan nilai p = 0.045 (p < 0,05) yang dapat diartikan sebagai adanya korelasi signifikan antara penggunaan RME terhadap tingkat kepuasan tenaga kesehatan. Kesimpulan: Implementasi RME di RS Permata Keluarga cabang Karawang telah memenuhi ekspektasi pengguna yang merefleksikan kesesuaian terhadap tingkat efektivitas dan adaptasi yang baik dari segi kinerja tenaga kesehatan.
Co-Authors Arsianti, Ade Permana, Noah Jefferson Talia, Ani