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Kesesuaian Uji Imunokromatografi dengan Enzyme Linked Fluorescent Assay untuk Deteksi Hepatitis B Surface Antigen Nomira Putri; Dianni Arma Wahyu Setia Ningsih; Bella Lucintarillova Arif Lubis
Journal of Mandalika Literature Vol. 5 No. 3 (2024)
Publisher : Institut Penelitian dan Pengembangan Mandalika (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jml.v5i3.3506

Abstract

Hepatitis B virus (VHB) infection is a global health problem. Hepatitis B surface antigen (HBsAg) as a serologic marker of hepaitis B virus infection can be detected by immunochromatography and Enzyme Linked Fluorescent Assay (ELFA). The aim of this study is to prove the agreement of immunochromatographic test with ELFA to detect HBsAg. This study used a cross-sectional analytic method on 30 patients for HBsAg examination at the Central Laboratory of Clinical Pathology. HBsAg was tested in patient's serum using immunochromatography and ELFA test. The agreement between the two methods was analyzed using the Kappa test. The Kappa coefficient between the two tests was 0.69 with good strength. The concordance of immunochromatographic assay with ELFA to detect HBsAg in this study gave good results.. : infeksi virus hepatitis b (VHB) merupakan maslah kesehatan global. Hepatitis B surface antigen (HBsAg) sebagai penanda serologi infeksi virus hepaitis B dapat dideteksi dengan uji imunokromatografi dan Enzyme Linked Fluorescent Assay (ELFA). Penelitian ini bertujuan untuk membuktikan kesesuaian uji imunokromatografi dengan ELFA untuk mendeteksi HBsAg. Penelitian ini menggunakan metode analitik potong lintang terhadap 30 pasien untuk pemeriksaan HBsAg di Laboratorium Sentral Patologi Klinik. Pemeriksaan HBsAg terhadap serum pasien menggunakan uji imunokromatografi dan ELFA. Kesesuaian antara kedua metode dianalisis menggunakan uji Kappa. Koefisien Kappa antara kedua pemeriksaan ini adalah 0,69 dengan kekuatan yang baik. Kesesuaian uji imunokromatografi dengan ELFA untuk mendeteksi HBsAg pada penelitian ini memberikan hasil yang baik.
The Analysis Study or Prevalence, Risk Factor, Diagnosis, Management and Complication of Pneumonia: A Comprehensive Systematic Review Bella Lucinta Rillova Arif Lubis; Dianni Arma Wahyu Setia Ningsih; Dewi Purwanti; Armaita; Linda Marni; Nomira Putri
The Indonesian Journal of General Medicine Vol. 9 No. 1 (2025): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/vby0y936

Abstract

Introduction: Community-acquired pneumonia (CAP) is a significant global health concern, often leading to severe complications such as bacteremia, respiratory failure, and septic shock. Bacteremia, detected through blood cultures, is a critical indicator of systemic infection and is associated with worse clinical outcomes, including prolonged ICU stays and higher mortality rates. With the rise of antimicrobial resistance and advancements in vaccine research, understanding the current epidemiology and management of CAP, particularly bacteremic CAP, is essential. Methods: This systematic review adheres to PRISMA 2020 guidelines and aims to evaluate the prevalence, risk factors, diagnosis, management, and complications of CAP, with a focus on bacteremia. Studies published between 2019 and 2025 were included, focusing on diagnostic methods, treatment strategies, and outcomes. Data were extracted from PubMed, Embase, Cochrane Library, and Web of Science. Results: Nine studies were included, highlighting trends in diagnostic practices, antibiotic stewardship, and the effectiveness of various treatment regimens. Key findings include increased use of C-reactive protein (CRP) and chest X-rays (CXR) in primary care, the benefits of syndromic molecular testing for pathogen-directed treatment, and the comparative effectiveness of antibiotic regimens such as beta-lactam plus macrolide (BL+M) and fluoroquinolones (FQ). Studies also emphasized the importance of clinical evaluation in interpreting diagnostic results and the need for optimized antibiotic use to reduce complications. Conclusion: This review shows the importance of evidence-based diagnostic and treatment strategies for CAP, particularly in managing bacteremia. While advancements in diagnostics and treatment have improved outcomes, challenges such as antibiotic resistance and underutilization of risk stratification tools remain. Future research should focus on optimizing diagnostic accuracy, treatment efficacy, and antibiotic stewardship to improve patient outcomes.
Hubungan Jenis Kelamin dan Usia dengan Kesehatan Mental di Kalangan Siswa Sekolah Menengah Atas di Kota Bukittinggi Bella Lucintarillova Arif Lubis; Dianni Arma Wahyu Setia Ningsih; Nomira Putri; Khalisah Muthmainnah
Jurnal Cahaya Mandalika ISSN 2721-4796 (online) Vol. 5 No. 1 (2024)
Publisher : Institut Penelitian Dan Pengambangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jcm.v5i2.2714

Abstract

Abstract: Mental health conditions in adolescent groups are important in the psychosocial development of adolescents. A group of mentally healthy teenagers is a valuable investment and asset for human resources in a country. Mental health is an important aspect in realizing overall health. Adolescence is an important period for developing social and emotional habits that are important for mental well-being. The aim of this research is to determine the picture of mental health in groups of teenagers in senior high schools in Bukittinggi city. The design of this research is an observational study with a cross sectional design. This research was conducted at a high school in Bukittinggi City with a total sample of 118 people taken based on the multistage stratified clustered sampling method. The results of the study showed that there was no relationship between age and gender on the mental disorders of high school students in Bukittinggi City (p>0.05).