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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal 'Aisyiyah Medika Bioscientia Medicina : Journal of Biomedicine and Translational Research
Abdillah, Novandra
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

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ANALISIS KUALITAS HIDUP PASIEN PENYAKIT GINJAL KRONIS YANG MENJALANI HEMODIALISIS Abdillah, Novandra; Asiani, Gema; Murni, Nani Sari; Wahyudi, Arie
Jurnal 'Aisyiyah Medika Vol 10, No 1: Februari 2025 Jurnal 'Aisyiyah Medika
Publisher : stikes 'aisyiyah palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36729/jam.v10i1.1316

Abstract

Latar Belakang: Penyakit Ginjal Kronis (PGK) merupakan masalah kesehatan global dengan prevalensi yang semakin meningkat, Hasil Riskesdas tahun 2018 menunjukkan adanya peningkatan prevalensi PGK di Indonesia pada kelompok usia ≥ 15 tahun, dimana tahun 2013 sebesar 0,2% dan tahun 2018 menjadi 0,38%. Tujuan: Menganalisis faktor – faktor yang berhubungan dengan kualitas hidup penderita Penyakit Ginjal Kronis yang menjalani hemodialisis. Metode: penelitian ini adalah kuantitatif analitik dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah seluruh pasien PGK yang menjalani hemodialisis secara reguler di Rumah Sakit Pusri Palembang sebanyak 70 orang. sampel dalam penelitian ini adalah total populasi sejumlah 70 responden. Penelitian ini telah di laksanakan 20 April - 10 Mei tahun 2024. Pengumpulan data menggunakan kuisioner. Analisis data bivariat menggunakan uji Chi-Square. Hasil: Tidak ada hubungan umur (p Value 0,973), jenis kelamin (p Value 0,790), Status pekerjaan (p Value 0,840), lama HD (p Value 0,698), Anemia (p Value 0,492), Adekuasi HD (p Value 0,138), Dukungan Keluarga (p Value 0,298), dan Hipertensi (p Value 0.431) dengan kualitas hidup responden.  Namun ada hubungan Pendidikan (p Value 0,042), Akses Vaskuler (p Value 0,020), dan Status Depresi (p Value 0,001) dengan kualitas hidup penderita Penyakit Ginjal Kronis yang menjalani hemodialisis di Rumah Sakit Pusri Palembang tahun 2024. Faktor yang paling dominan Status Depresi (OR 10,131). Saran: RS PUSRI Palembang dapat menyusun rencana dan menjalankan program kegiatan bagi pasien yang melakukan hemodialisis di Rumah Sakit Pusri untuk meminimalisir depresi pasien. Kata Kunci: PGK, Kualitas Hidup, Hemodialisis, Depresi
Gut Microbiota in Chronic Kidney Disease: A Narrative Literature Review Abdillah, Novandra; Zulklhair Ali; Novadian; Ian Effendi; Suprapti; Elfiani; Rery TF Yuniarti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 4 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i4.976

Abstract

Chronic kidney disease (CKD) is a growing public health problem related to loss of kidney function and cardiovascular disease as the main causes of morbidity and mortality in CKD. It is known that CKD is associated with intestinal dysbiosis. There is an influence of the gut microbiota on the gut-kidney axis and it works reciprocally: on the one hand, CKD significantly changes the composition and function of the gut microbiota. On the other hand, gut microbiota is able to manipulate the processes that cause the emergence and progression of CKD through inflammatory, endocrine and neurological pathways. Understanding the complex interactions between gut and kidney microbiota may provide novel nephroprotective interventions to prevent the progression of CKD by therapeutically targeting balance of gut microbiota composition.
Gut Microbiota in Chronic Kidney Disease: A Narrative Literature Review Abdillah, Novandra; Zulklhair Ali; Novadian; Ian Effendi; Suprapti; Elfiani; Rery TF Yuniarti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 4 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i4.976

Abstract

Chronic kidney disease (CKD) is a growing public health problem related to loss of kidney function and cardiovascular disease as the main causes of morbidity and mortality in CKD. It is known that CKD is associated with intestinal dysbiosis. There is an influence of the gut microbiota on the gut-kidney axis and it works reciprocally: on the one hand, CKD significantly changes the composition and function of the gut microbiota. On the other hand, gut microbiota is able to manipulate the processes that cause the emergence and progression of CKD through inflammatory, endocrine and neurological pathways. Understanding the complex interactions between gut and kidney microbiota may provide novel nephroprotective interventions to prevent the progression of CKD by therapeutically targeting balance of gut microbiota composition.
Co-Authors Elfiani Gema Asiani Ian Effendi Nani Sari Murni Novadian Rery TF Yuniarti Suprapti Wahyudi, Arie Zulklhair Ali