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All Journal Jurnal Sains dan Kesehatan Jurnal Nurse Protein: Jurnal Ilmu Keperawatan dan Kebidanan
Cici Farhana Ambarwanty Mohtar
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Health Professions Nursing Public Health

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Journal : Jurnal Nurse

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Efek Pemberian Ekstrak Jamur Shiitake (Lentinula Edodes) Terhadap Aktivitas Superoksida Dismutase Pada Tikus Yang Diinduksi Karbon Tetraklorida Cici Farhana Ambarwanty Mohtar; Suci Indah Budiarti
Jurnal Nurse Vol. 4 No. 1 (2021): Januari : Jurnal Nurse
Publisher : STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/nurse.v4i1.233

Abstract

Shiitake mushrooms (Lentinula edodes) is edible mushrooms and medicinal mushrooms because they contain high nutrients and bioactive compounds, such as flavonoids, phenols and terpenoids that can function as antioxidants. Antioxidants are molecules that are able to ward off free radicals in the body, although naturally the body can ward off free radicals through enzymatic (endogenous) antioxidants, such as superoxide dismutase (SOD). But if too many free radicals enter the body, it can cause oxidative stress so that endogenous antioxidants cannot work properly, so exogenous antioxidants are needed such as those found in ethanol extracts of L. edodes. One of the materials that can become free radicals is carbon tetrachloride (CCl4). This study aims to determine the effect of ethanol extract of L.edodes on levels of SOD, in rats and determine the most effective dose of ethanol extract on increasing levels of SOD and blood catalase in rats induced by CCl4. This research carried out experimentally with a Completely Randomized Design (CRD) with variation of ethanol extract concentration (250; 500; 750 ppm). The results showed that the extraction of shiitake mushroom extract has an effect on increase in the levels of superoxide dismutase and catalase in rats induced carbon tetrachloride. The concentration of ethanol extract of 500mg/kg BW of rats was the most effective concentration for increasing superoxide dismutase and the ethanolic extract of L. edodes had antioxidant activity.
Hubungan Kadar Kolesterol Total dengan Tekanan Darah pada Pasien Hipertensi di Rumah Sakit Tingkat III 04.06.01 Wijaya Kusuma Purwokerto Cici Farhana Ambarwanty Mohtar; Oksita Asri Widyayanti; Martha Intan Nagari Pratiwi
Jurnal Nurse Vol. 5 No. 2 (2022): Juli : Jurnal Nurse
Publisher : STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/nurse.v5i2.235

Abstract

Hypertension is still a problem in Indonesia and in other countries. Risk factors that cause hypertension pain rates are high total cholesterol levels. High cholesterol levels are experienced by many people with hypertension, will result in the formation of plaque that appears on the surface of the artery wall and has an impact on shrinking the diameter of blood vessels. The occurrence of blockages in blood vessels, which results in blood vessels having lumen (holes) then blood vessels will narrow and the elasticity of blood vessels can be reduced, this can cause hypertension. The purpose of this study was to determine the relationship between total cholesterol levels and the degree of hypertension in patients at Level III Hospital 04.06.01 Wijaya Kusuma Purwokerto. The results showed that the degree of hypertension of patients at Level III Hospital 04.06.01 Wijaya Kusuma Purwokerto there were patients with grade II hypertension as much as 54.1%, patients with grade I hypertension as much as 45.9%. Cholesterol levels with a high risk in patients as much as 54.1%, moderate cholesterol levels as much as 45.9%. The p value on the chi-square test is 0.022 (p<0.05), Fhit > Ftable means that there is a significant relationship between cholesterol levels and the degree of hypertension
Co-Authors Delita Septining Tyas Epsi Marwati Esa Dhiandani Martha Intan Nagari Pratiwi Oksita Asri Widyayanti Suci Indah Budiarti Utami Pratyastiti Setyarini