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All Journal Andalas obstetrics and gynecology journal Jurnal Sains dan Teknologi
Yulia Margaretta Sari
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Rectovaginal Fistula Due To Chronic Perineal Tear; A Case Report Yulia Margaretta Sari; Juan Habli Soufal
INSOLOGI: Jurnal Sains dan Teknologi Vol. 3 No. 3 (2024): Juni 2024
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v3i3.3624

Abstract

An abnormal connection that exists between two epithelial surfaces or lumens of the rectum that reaches into the vagina is known as a recto-vaginal fistula (RVF). RVF is one unfortunate consequence of the underlying condition, such as trauma or surgery. According to the patient recap of the urogynecology clinic at M Djamil Hospital Padang (2023), from January to September, 6 patients had cases of rectovaginal fistula that needed to be repaired. Treatment of the underlying condition, the fistula, and its associated complications all fall under the umbrella of RVF management. Given that obstetrics, procedure is still the main cause in this case, the role of the field of urogynecology in the management of surgical interventions is important to maintain the quality of life of a woman. In this case report we present a case report of a 24-year-old woman with rectovaginal fistula and anal incontinence caused by chronic total perineal tear. The patient complained of feces discharge from the vagina since giving spontaneous birth to the first. Physical examination found defects in the internal sphincter (IAS) and external sphincter (EAS) at 11 until 14 o'clock. The patient then underwent sphincteroplasty and perineorrhaphy and showed improvement after surgical intervention
Pelvic Floor Distress Inventory (PFDI)-20 Score In Patients With Pelvic Organ Prolaps (POP) Yulia Margaretta Sari; Mila Permata Sari
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.693-702.2024

Abstract

Background :Pelvic organ prolapse (POP) is a common and benign condition in women. It was the fall of one or more components of the vagina and uterus, which allows surrounding organs to herniate into the vaginal area, a disease known as cystocele, rectocele, or enterocele. The PFDI-20 score has been used to evaluate symptoms and quality of life in all POP patients. Objectives : To analyze the PFDI-20 score in patients with POP. Method : An observational study involving POP patients was undertaken at RSUP Dr. M. Djamil Padang from December 2023 to January 2024. The variables include demographic information (age, parity, obstetric and gynecological history) gathered from medical records, as well as complaints and POP symptoms obtained through an interview using the Indonesian PFDI-20 score. Data was analyzed univariately and bivariately. Statistical significance was set at p<0.05, and statistical analyzes were conducted using Kruskal-Wallis. The statistical program used for the analysis was SPSS 25.0. Results : Twenty-eight ladies participated. Their average age was 64.43 years (SD=10.49), parity number was 4.5 (SD=2.2), and PDFI-20 score was 136.61 (SD=54.21). In terms of POP, 53.6% (15) were IV. In terms of prolapse type, all patients had uterine prolapses, with the majority also having cystocele and rectocele (96.4%). Total vaginal hysterectomy (TVH) was performed in 82.1% (23), with over half of the patients undergoing anterior colporrhaphy (AC), posterior colpoperineorrhaphy, or colpocleisis. The majority of the complaints concerned inactive sexual activity (92.0%) and frequency (64.3%). The bivariate analysis with Kruskal Wallis test revealed no statistically significant relationships between PDFI-20 score and degree of POP (p<0.05). Conclusion : Although we were unable to identify a significant correlation, the PFDI-20 score was demonstrated to be a reliable tool for assessing symptoms and quality of life in all POP patients.
A Rare Case of Female Urethral Diverticulum Muhammad Iqbal; Yulia Margaretta Sari; Bobby Indra Utama
Andalas Obstetrics And Gynecology Journal Vol. 9 No. 2 (2025)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.9.2.305-317.2025

Abstract

Background: DU is a varied and challenging case of pelvic surgery because the diagnosis is difficult to make. Symptoms that appear in women vary, ranging from incidental findings, lumps or swelling, and pain in the vagina, as well as discharge from the urethra with a periurethral mass. Objective: In this report, we report a case of DU in a 32-year-old woman who complained of a painful lump in her genitals. This patient underwent transvaginal urethral diverticulectomy and successfully resolved the symptoms of urethral diverticulum he experienced. Methods: Management of urethral diverticulum in this report, namely by history taking, physical examination, supporting examination consisting of transvaginal and transperineal ultrasound, as well as cystourethroscopy before excision and reconstruction of the urethral diverticulectomy is carried out on this patient. Results: This patient had a successful transvaginal urethral diverticulectomy, with no early post-surgical complications found. Conclusion: Reducing the rate of problems following surgery is possible by adhering to the excision and reconstruction principles of urethral diverticulectomy.
Factors Associated with Stress Urinary Incontinence During Pregnancy at Pasar Kuok Community Health Center Maulana, Muhammad Iqbal; Yulia Margaretta Sari
Andalas Obstetrics And Gynecology Journal Vol. 9 No. 2 (2025)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.9.2.224-230.2025

Abstract

Objective: This study aimed to analyze the relationship between maternal age, parity, and trimester of pregnancy with stress urinary incontinence (SUI) severity, measured using the International Consultation on Incontinence Questionnaire (ICIQ) score, among 102 pregnant women at Pasar Kuok Health Center. Method: A cross-sectional study was conducted involving pregnant women who completed the ICIQ questionnaire. Data on maternal age, parity, and trimester of pregnancy were collected and analyzed using statistical tests to determine their association with SUI severity. Result: The mean ICIQ scores varied across age groups, parity, and pregnancy trimesters, with the highest scores observed in women aged 31–38 years, multiparous women, and those in the third trimester. However, statistical analysis revealed no significant associations between ICIQ scores and maternal age (p = 0.584), parity (p = 0.945), or trimester of pregnancy (p = 0.136). Conclusion: These findings suggest that maternal age, parity, and trimester of pregnancy may not independently influence SUI severity during pregnancy. Further research is needed to explore other potential contributors to SUI. Early screening and management strategies, including pelvic floor muscle training, remain essential to improving maternal quality of life.
Obstructed Hemivagina and Ipsilateral Renal Agenesis (OHVIRA) Syndrome: A Rare Case Report Ega Atista; Yulia Margaretta Sari
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.163-169.2026

Abstract

Introduction: The Herlyn-Werner-Wunderlich (HWW) syndrome, also known as obstructed hemivagina and ipsilateral renal agenesis (OHVIRA), is a rare form of Mullerian Duct Anomalies (MDA). The patient with OHVIRA syndrome has dysmenorrhea, abdominal pain, and a lump in the belly. Although the exact cause and pathology of OHVIRA syndrome are unknown, early diagnosis and treatment can reduce acute symptoms and preserve normal fertility. Case Report: This article reports a case of 15 a 15-year-old woman who complained of foul mucopurulent discharge. Ultrasound finding uterus didelphys, right obstructed hemivagina with resultant pyocolpos, and suspected of right renal agenesis. The patient was diagnosed with OHVIRA syndrome. The patient underwent vaginal septal resection, and the pyocolpos was drained. Discussion: Intraoperatively, a completely obstructed longitudinal vaginal septum was identified on the right hemivagina, with purulent fluid consistent with pyocolpos. After septal resection, adequate drainage was achieved and communication between both hemivaginas was established. Postoperatively, the patient showed clinical improvement, with resolution of vaginal discharge and relief of vaginal obstruction. No intraoperative or immediate postoperative complications were observed. During short-term follow-up, the patient remained asymptomatic, with no evidence of recurrent obstruction or infection. Conclusion: This case highlights several important aspects of OHVIRA syndrome, including its atypical postpartum presentation, diagnostic challenges, and unpredictable reproductive outcomes. Ultrasonography plays a key role in early detection. Vaginal septal resection and drainage are effective in relieving symptoms and preventing complications. Reporting this rare presentation contributes to improved awareness and timely management of OHVIRA syndrome in adolescents.
The Role of Transforming Growth Factor Beta (TGF-β) in Pelvic Organ Prolapse : A Systematic Review Yulia Margaretta Sari; Bobby Indra Utama; Zelly Dia Rofinda; Elliyanti, Aisyah
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.58-69.2026

Abstract

Introduction: Pelvic organ prolapse (POP) is a gynaecological disorder with a rising prevalence, significantly affecting quality of life. While the pathogenesis of POP is multifactorial, alterations in the extracellular matrix (ECM) have been implicated, particularly the role of transforming growth factor-beta (TGF-β) in ECM remodelling. However, the precise relationship between TGF-β and POP remains unclear. Methods: A systematic review was conducted following PRISMA guidelines. Relevant studies were identified from PubMed, Scopus, Web of Science, and the Cochrane Library. Inclusion criteria focused on studies investigating TGF-β expression in women with POP. Data extraction included study design, patient demographics, TGF-β detection methods, and key findings. Results: Analysis of nine studies revealed mixed findings. Four studies reported a significant reduction in TGF-β1 expression in POP patients, suggesting impaired ECM regulation via the TGF-β1/Smad3 pathway. Three studies found no significant differences in TGF-β levels between POP and control groups, while one study linked increased TGF-β1 levels to severe prolapse, possibly as a compensatory response. Variations in methodology, sample size, and patient characteristics contributed to inconsistencies across studies. Conclusion: Current evidence suggests that TGF-β1 plays a role in POP pathogenesis, with lower levels potentially weakening ECM integrity and higher levels in advanced cases reflecting a failed reparative response. Further research is needed to explore TGF-β interactions with other biomarkers and assess its potential as a therapeutic target.
Co-Authors Aisyah Elliyanti Bobby Indra Utama Ega Atista Juan Habli Soufal Maulana, Muhammad Iqbal Mila Permata Sari Muhammad Iqbal Zelly Dia Rofinda