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Pelvic Floor Distress Inventory (PFDI)-20 Score In Patients With Pelvic Organ Prolaps (POP) Yulia Margaretta Sari; Mila Permata Sari
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.693-702.2024

Abstract

Background :Pelvic organ prolapse (POP) is a common and benign condition in women. It was the fall of one or more components of the vagina and uterus, which allows surrounding organs to herniate into the vaginal area, a disease known as cystocele, rectocele, or enterocele. The PFDI-20 score has been used to evaluate symptoms and quality of life in all POP patients. Objectives : To analyze the PFDI-20 score in patients with POP. Method : An observational study involving POP patients was undertaken at RSUP Dr. M. Djamil Padang from December 2023 to January 2024. The variables include demographic information (age, parity, obstetric and gynecological history) gathered from medical records, as well as complaints and POP symptoms obtained through an interview using the Indonesian PFDI-20 score. Data was analyzed univariately and bivariately. Statistical significance was set at p<0.05, and statistical analyzes were conducted using Kruskal-Wallis. The statistical program used for the analysis was SPSS 25.0. Results : Twenty-eight ladies participated. Their average age was 64.43 years (SD=10.49), parity number was 4.5 (SD=2.2), and PDFI-20 score was 136.61 (SD=54.21). In terms of POP, 53.6% (15) were IV. In terms of prolapse type, all patients had uterine prolapses, with the majority also having cystocele and rectocele (96.4%). Total vaginal hysterectomy (TVH) was performed in 82.1% (23), with over half of the patients undergoing anterior colporrhaphy (AC), posterior colpoperineorrhaphy, or colpocleisis. The majority of the complaints concerned inactive sexual activity (92.0%) and frequency (64.3%). The bivariate analysis with Kruskal Wallis test revealed no statistically significant relationships between PDFI-20 score and degree of POP (p<0.05). Conclusion : Although we were unable to identify a significant correlation, the PFDI-20 score was demonstrated to be a reliable tool for assessing symptoms and quality of life in all POP patients.
The Efficacy of Dequalinium Chloride Against Vulvovaginitis in Pregnancy Mila Permata Sari; Djanas, Dovy; Putra, Andani Eka
Andalas Obstetrics And Gynecology Journal Vol. 9 No. 1 (2025)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.9.1.49-62.2025

Abstract

Introduction: Vulvovaginitis affects pregnancy outcomes and managing it involves the use of metronidazole or nystatin, which can cause local or systemic side effects. Dequalinium chloride (DQC) is suggested as a new treatment option for vulvovaginitis during pregnancy with minimal side effects. Objective: To compare the effectiveness of dequalinium chloride (DQC) versus metronidazole + nystatin (MN) in treating vulvovaginitis in pregnant women during their second and third trimesters. Method: A single-blind randomized controlled trial was conducted at the Andalas Public Health Center, Padang, from January to May 2024. Pregnant women in their second and third trimesters, meeting the inclusion and exclusion criteria, were enrolled. The participants were randomly assigned to either the DQC or MN group. Vaginal swabs were taken before and after a 6-day treatment, and PCR analysis was performed. Results: Eighteen patients were treated with DQC and MN. Most participants had bacterial vaginosis (DQC 78%, MN 83%), with half having candidiasis (DQC and MN 50%) and fewer cases of trichomoniasis (28% in both groups). Significant improvements were seen in the DQC group for symptoms (p=0.000), Gardnerella vaginalis (p=0.035), and Candida albicans (p=0.021). In the MN group, significant improvements were noted for symptoms (p=0.000) and Gardnerella vaginalis (p=0.002). No significant differences were observed between the groups for symptom resolution or microbial reduction. Conclusion: DQC is as effective as metronidazole + nystatin in treating bacterial vaginosis and candidiasis in pregnancy. Keywords: Vulvovaginitis, pregnancy, dequalinium chloride, metronidazole, nystatin