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ANTI-INFLAMMATORY EFFECT OF LEAF ETHANOL EXTRACT OF CAT'S KUMIZE (Orthosiphon stamineus Benth) IN MALE WHITE RATS OF WISTAR STRAINS Meyana Marbun; Dian Permata Nasution; Beta Hanindiya; Mustaruddin; Yulia Delfahedah; Arsiaty
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 3 (2021): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v3i.244

The cat's whiskers plant is empirically used by the community for the treatment of gout and rheumatism. This research was conducted with the aim of knowing the anti-inflammatory power of cat's kumis (Orthosihon stamineus Benth) leaf extract. This study was a quasi-experimental study with a one-way completely randomized design. Kumis Kucing leaf extract was extracted using 70% ethanol. A total of 25 male wistar rats aged 2-3 months, weighing 150-200g were divided into 5 groups. Each group was treated orally with distilled water (negative control), diclofenac sodium 2.25 mg/kg BW (positive control). Kumis leaf ethanol extract tested at doses of 123, 245 and 490 mg/kgBB. Treatment 1 hour before the feet of rats were inflamed with 1% sublantar carrageenin. Measurements of the rat's foot volume were carried out every 0.5 hours for 6.5 hours. The obtained average edema volume curve is used to calculate AUC (Area Under The Curve) and the obtained AUC is used to calculate DAI (Anti-Inflammatory Power). The AUC and DAI data were tested statistically with one way Anava and followed by LSD with a 95% confidence level. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded 33.11%; 52.64% and 64.12% respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively.

THE RELATIONSHIP OF KNOWLEDGE AND ATTITUDES OF YOUTH WOMEN TO PREVENTION OF LEVIATION IN THE WORKING AREA OF SINDAR RAYA PUSKESMAS SIMALUNGUN DISTRICT Beta Hanindiya; Arsiaty; Mustaruddin
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 3 (2021): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v3i.250

Based on the findings of the researchers, there were 5 young women in the Working Area of the Sindar Raya Health Center, Simalungun Regency, experiencing vaginal discharge. This research was conducted to find out whether there is a relationship between the knowledge and attitudes of young women towards preventive measures for vaginal discharge in the Working Area of the Sindar Raya Health Center, Simalungun Regency, in 2017. This type of research is descriptive with the population in this study being all young women in the Working Area of the Sindar Raya Health Center, Regency Simalungun in 2017, namely 108 people who were sampled as many as 85 people using the simple random sampling technique, which is a simple random sampling method. The results of this study showed that the majority had good knowledge, namely 42 people (49.4%), while the minority had less knowledge, namely 17 people (20%). The majority had an attitude of agreeing, namely 58 people (68.2%), while a minority had an attitude of disagreeing, namely 27 people (31.8%). The majority had good leucorrhoea prevention measures as many as 57 people (67.1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of the Sindar Raya Health Center, Simalungun Regency, 2017. 2%) while the minority had a disapproving attitude, namely 27 people (31.8%). The majority had good leucorrhoea prevention measures as many as 57 people (67.1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of the Sindar Raya Health Center, Simalungun Regency, 2017. 2%) while the minority had a disapproving attitude, namely 27 people (31.8%). The majority had good leucorrhoea prevention measures as many as 57 people (67.1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of the Sindar Raya Health Center, Simalungun Regency, 2017. 1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of the Sindar Raya Health Center, Simalungun Regency, 2017. 1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of the Sindar Raya Health Center, Simalungun Regency, 2017. From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of the Sindar Raya Health Center, Simalungun Regency, 2017. From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of the Sindar Raya Health Center, Simalungun Regency, 2017.

Antioxidant Activity Test of Ethanol Extract of Andaliman Fruit (Zanthoxylum Acanthopodium DC.) on Superoxide Dismutase (SOD) Levels in Rats Arsiaty; Yulia Delfahedah; Andre Bastian Manik; Nurasima Kurniati Damanik
International Journal of Public Health Excellence (IJPHE) Vol. 1 No. 2 (2022): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v1i2.330

Free radicals are compounds or molecules that contain one or more unpaired electrons in their outer orbitals. If the production of free radicals is excessive, it can cause oxidative damage which ends in cell death resulting in the acceleration of various degenerative diseases. To neutralize the work of free radicals, external antioxidants are needed. Andaliman (Zanthoxylum acanthopodium DC) is a source of natural antioxidants that contain flavonoids that can neutralize free radicals. This research included sample preparation, examination of simplicia characteristics, screening of simplicia phytochemicals, extract preparation, determination of SOD activity spectrophotometrically using reagents. A total of 30 rats were divided into 6 groups consisting of the control group, the stress-induced group, the comparison group, and the three stress-induced and EEBA groups with doses of 75 mg/kg, 150 mg/kg, and 300 mg respectively. /kg bw. Stress induction was carried out by administering EEBA for 7 days and continued by administering EEBA together with doxorubicin for the next 2 days. The results showed that the average SOD level in the control group was (4.626 0.2583), the doxorubicin group (1.956+ 0.0879), the EEBA group 75 mg kg body weight (2.444 0.0844), the EEBA group 150 mg/kg body weight ( 3.052 +0.1139), the EEBA 300 mg/kg body weight (3.646+0.1739) and the Routine 50 mg/kg body weight 5.594 + 0.2056), EEBA had higher SOD activity when compared to the doxorubicin group. Based on the statistical results, SOD activity increased with the increase in the dose of EEBA given and showed a significant difference (p<0.05) between the EPBA group and the doxorubicin group. Observations on liver tissue in the group given EEBA showed better conditions than the liver in the doxorubicin group.

The Relationship Between Family Support on the Care Process of Lulmon Tubercolosis Patients in the Working Area of Rahuning Health Center, Rahuning District, Asahan Regency Arsiaty; Manik, Andre Bastian
International Journal of Public Health Excellence (IJPHE) Vol. 2 No. 2 (2023): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v2i2.353

The success of tuberculosis treatment depends on the patient's knowledge and support from the family. There is no self-effort or motivation from the family who does not provide support for complete treatment. It will affect patient adherence to taking the drug. A study was conducted to find out whether there is a relationship between family support and the patient's recovery process. Pulmonary Tuberculosis in the Working Area of the Rabuning Health Center, Rahuning District, Asahan Regency in 2019 This research was conducted in July-September 2019 with a population of 32 respondents. The sampling was carried out using total sampling. The results of this study found that from 15 respondents who received emotional support, all of them received healing compared to less supportive 6 respondents out of 8 respondents, who did not support 1 respondent and 9 respondents Out of 15 respondents who received information support all got healing compared to less supportive 6 respondents and 10 respondents, who did not support 1 respondent out of 9 respondents. Of the 10 respondents who received instrumental support, all of them got healing compared to less supportive, 11 of 14 respondents who did not support the respondent and 8 respondents. the patient did not experience recovery at all. This research is expected to provide benefits to families in assisting patients in obtaining recovery by providing emotional support, informational support, instrumental support and appreciation support regarding the importance of family support in helping to increase patient knowledge so that it can affect recovery.

Antioxidant Activity Test of Ethanol Extract of Andaliman Fruit (Zanthoxylum Acanthopodium DC.) on Superoxide Dismutase (SOD) Levels in Rats Arsiaty; Yulia Delfahedah; Andre Bastian Manik; Nurasima Kurniati Damanik
International Journal of Public Health Excellence (IJPHE) Vol. 1 No. 2 (2022): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v1i2.330

Free radicals are compounds or molecules that contain one or more unpaired electrons in their outer orbitals. If the production of free radicals is excessive, it can cause oxidative damage which ends in cell death resulting in the acceleration of various degenerative diseases. To neutralize the work of free radicals, external antioxidants are needed. Andaliman (Zanthoxylum acanthopodium DC) is a source of natural antioxidants that contain flavonoids that can neutralize free radicals. This research included sample preparation, examination of simplicia characteristics, screening of simplicia phytochemicals, extract preparation, determination of SOD activity spectrophotometrically using reagents. A total of 30 rats were divided into 6 groups consisting of the control group, the stress-induced group, the comparison group, and the three stress-induced and EEBA groups with doses of 75 mg/kg, 150 mg/kg, and 300 mg respectively. /kg bw. Stress induction was carried out by administering EEBA for 7 days and continued by administering EEBA together with doxorubicin for the next 2 days. The results showed that the average SOD level in the control group was (4.626 0.2583), the doxorubicin group (1.956+ 0.0879), the EEBA group 75 mg kg body weight (2.444 0.0844), the EEBA group 150 mg/kg body weight ( 3.052 +0.1139), the EEBA 300 mg/kg body weight (3.646+0.1739) and the Routine 50 mg/kg body weight 5.594 + 0.2056), EEBA had higher SOD activity when compared to the doxorubicin group. Based on the statistical results, SOD activity increased with the increase in the dose of EEBA given and showed a significant difference (p<0.05) between the EPBA group and the doxorubicin group. Observations on liver tissue in the group given EEBA showed better conditions than the liver in the doxorubicin group.

THE RELATIONSHIP OF PHARMACEUTICAL SERVICES TO PATIENT SATISFACTION AT THE PUSKESMAS TRADING BANDAR DISTRICT SIMALUNGUN DISTRICT Yulia Delfahedah; Arsiaty
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 3 No. 2 (2022): June
Publisher : PT. Radja Intercontinental Publishing

The research entitled The Relationship of Pharmaceutical Services to Patient Satisfaction at the Trading Health Center, Bandar District, Simalungun Regency was conducted in July - August 2019. The purpose of this study was to find out how the application of pharmaceutical service standards at the Puskesmas, the level of patient satisfaction and the effect of applying pharmaceutical service standards on satisfaction Patients This research is a descriptive survey research that is cross-sectional. Data collection was carried out by observation by researchers to find out the application of pharmaceutical service standards and to conduct interviews with patients to determine the level of satisfaction with pharmaceutical services. Data was collected from 170 respondents in July-August 2019 at the Trading Health Center, Bandar District, Simalungun Regency, The application of pharmaceutical service standards studied in this study is human resources, facilities and infrastructure for the management of drugs and medical consumables, clinical pharmacy services and service quality control. The criteria for measuring the level of satisfaction include five variables, namely reliability, responsiveness, confidence, empathy and tangible facilities. The results showed that the implementation of pharmaceutical service standards at the Commercial Health Center, namely the application of pharmaceutical service standards at the Commercial Health Center, was included in the less category. Based on the average value of total patient satisfaction, the level of patient satisfaction at the Jawa Maraja Health Center was included in the satisfied category. The application of pharmaceutical service standards at the Commercial Health Center to patient satisfaction with the Mann-Whiteney Test obtained a sig value of <0.05.

THE RELATIONSHIP OF KNOWLEDGE ATTITUDE AND DIETARY COMPLIANCE WITH BLOOD SUGAR LEVELS IN DIABETES MELLITUS PATIENTS IN THE INTERNAL DISEASE CLINIC OF VITA Arsiaty; Yulia Delfahedah
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 3 No. 3 (2022): September
Publisher : PT. Radja Intercontinental Publishing

Diabetes Mellitus (DM) is a chronic metabolic disorder caused by impaired insulin secretion, insulin resistance, or a combination of both. Controlling blood sugar levels is the main thing for DM sufferers, one of which is with diet/nutrition therapy. Correct diet therapy is based on basic knowledge and attitudes. good for controlling blood sugar This study aims to determine the relationship between knowledge, attitudes and dietary compliance with blood sugar levels in DM patients at the Internal Medicine Polyclinic at Vita Insan Hospital in 2019. This research is an analytic study with a cross-sectional design, carried out from July 2019. the sample used a purposive sampling technique consisting of 52 DM patients. The data taken included aspects of knowledge, attitudes.diet adherence (primary) and blood sugar levels (secondary) Computerized data processing using Chi Square test Univariate analysis results showed 69.2% of patients had uncontrolled blood sugar levels, 59.6% of patients had insufficient knowledge but 59.6% patients had a positive attitude towards efforts to control blood sugar and 53.8% of patients were disobedient to the diet given. From Bivariate analysis there was a significant relationship between knowledge, dietary adherence and blood sugar levels (p<0.05), but for attitudes there was no significant relationship (p-0.05) Suggestions for health workers to further improve patient understanding of the DM diet so that patient's blood sugar levels are controlled by providing education and developing information provision,for the family it is necessary to provide support and motivation so that the patient is on a diet.

STUDY OF PRESCRIPTION PROFILE OF PATIENTS WITH BRONCHIAL ASTHMA AT PARSOBURAN COMMUNITY HEALTH CITY PEMATANGSIANTAR PERIOD JANUARY-MARCH 2017 Yulia Delfahedah; Arsiaty
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 1 No. 4 (2020): December
Publisher : PT. Radja Intercontinental Publishing

Bronchial asthma has varying incidence rates in different countries, but there is a tendency for this disease to increase in number, even though asthma medications have been developed. This study aims to determine the pattern of treatment of bronchial asthma in patients at the Parsoburan Health Center, Pematangsiantar City for the period January-March 2017. This research was a non-experimental (observational) descriptive study conducted using a retrospective method. The data used are medical records of bronchial asthma patients. The results of the study showed that in the January-March 2017 period there were 18 cases of bronchial asthma. The gender distribution of bronchial asthma patients was 66.7% male and 33.3% female, while the age distribution of bronchial asthma patients was divided into 4 groups, namely, Toddlers (0≤5 years) by 33.3%, children (5<n<12 years) by 5.6%, adults (12<n<65 years) by 38.9%, and elderly (> 65 years) of 22.2% The general description of prescribing the highest number of drugs given to bronchial asthma patients in one prescription are 5 and 6 drugs each of 38.9%, the distribution of drug classes used for therapy includes, bronchodilators 25, 7%, mucolytic 18.5%, corticosteroid 15.5%, anti-microbial 15.5%, anti-hypoxemia 4.1%, analgesic 6.2%, anti-histamine 3.1% and accompanying drugs (anti- diabetic, anti-epileptic, anti-hypertensive, anti-angina, and vitamins) given at 1% each. Distribution of discrepancies in drug administration based on the Indonesian National Drug Informatorium standard of 17.5%, based on the Physicians Drug Handbook standard of 0%,

The Relationship Between Family Support on the Care Process of Lulmon Tubercolosis Patients in the Working Area of Rahuning Health Center, Rahuning District, Asahan Regency Arsiaty; Manik, Andre Bastian
International Journal of Public Health Excellence (IJPHE) Vol. 2 No. 2 (2023): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v2i2.353

The success of tuberculosis treatment depends on the patient's knowledge and support from the family. There is no self-effort or motivation from the family who does not provide support for complete treatment. It will affect patient adherence to taking the drug. A study was conducted to find out whether there is a relationship between family support and the patient's recovery process. Pulmonary Tuberculosis in the Working Area of the Rabuning Health Center, Rahuning District, Asahan Regency in 2019 This research was conducted in July-September 2019 with a population of 32 respondents. The sampling was carried out using total sampling. The results of this study found that from 15 respondents who received emotional support, all of them received healing compared to less supportive 6 respondents out of 8 respondents, who did not support 1 respondent and 9 respondents Out of 15 respondents who received information support all got healing compared to less supportive 6 respondents and 10 respondents, who did not support 1 respondent out of 9 respondents. Of the 10 respondents who received instrumental support, all of them got healing compared to less supportive, 11 of 14 respondents who did not support the respondent and 8 respondents. the patient did not experience recovery at all. This research is expected to provide benefits to families in assisting patients in obtaining recovery by providing emotional support, informational support, instrumental support and appreciation support regarding the importance of family support in helping to increase patient knowledge so that it can affect recovery.

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