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ANTI-INFLAMMATORY EFFECT OF LEAF ETHANOL EXTRACT OF CAT'S KUMIZE (Orthosiphon stamineus Benth) IN MALE WHITE RATS OF WISTAR STRAINS Meyana Marbun; Dian Permata Nasution; Beta Hanindiya; Mustaruddin; Yulia Delfahedah; Arsiaty
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 3 (2021): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v3i.244

Abstract

The cat's whiskers plant is empirically used by the community for the treatment of gout and rheumatism. This research was conducted with the aim of knowing the anti-inflammatory power of cat's kumis (Orthosihon stamineus Benth) leaf extract. This study was a quasi-experimental study with a one-way completely randomized design. Kumis Kucing leaf extract was extracted using 70% ethanol. A total of 25 male wistar rats aged 2-3 months, weighing 150-200g were divided into 5 groups. Each group was treated orally with distilled water (negative control), diclofenac sodium 2.25 mg/kg BW (positive control). Kumis leaf ethanol extract tested at doses of 123, 245 and 490 mg/kgBB. Treatment 1 hour before the feet of rats were inflamed with 1% sublantar carrageenin. Measurements of the rat's foot volume were carried out every 0.5 hours for 6.5 hours. The obtained average edema volume curve is used to calculate AUC (Area Under The Curve) and the obtained AUC is used to calculate DAI (Anti-Inflammatory Power). The AUC and DAI data were tested statistically with one way Anava and followed by LSD with a 95% confidence level. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded 33.11%; 52.64% and 64.12% respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively.
THE RELATIONSHIP OF KNOWLEDGE AND ATTITUDES OF YOUTH WOMEN TO PREVENTION OF LEVIATION IN THE WORKING AREA OF SINDAR RAYA PUSKESMAS SIMALUNGUN DISTRICT Beta Hanindiya; Arsiaty; Mustaruddin
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 3 (2021): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v3i.250

Abstract

Based on the findings of the researchers, there were 5 young women in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, experiencing vaginal discharge. This research was conducted to find out whether there is a relationship between the knowledge and attitudes of young women towards preventive measures for vaginal discharge in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, in 2017. This type of research is descriptive with the population in this study being all young women in the Working Area of ​​the Sindar Raya Health Center, Regency Simalungun in 2017, namely 108 people who were sampled as many as 85 people using the simple random sampling technique, which is a simple random sampling method. The results of this study showed that the majority had good knowledge, namely 42 people (49.4%), while the minority had less knowledge, namely 17 people (20%). The majority had an attitude of agreeing, namely 58 people (68.2%), while a minority had an attitude of disagreeing, namely 27 people (31.8%). The majority had good leucorrhoea prevention measures as many as 57 people (67.1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, 2017. 2%) while the minority had a disapproving attitude, namely 27 people (31.8%). The majority had good leucorrhoea prevention measures as many as 57 people (67.1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, 2017. 2%) while the minority had a disapproving attitude, namely 27 people (31.8%). The majority had good leucorrhoea prevention measures as many as 57 people (67.1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, 2017. 1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, 2017. 1%) while the minority had bad leucorrhoea prevention measures as many as 28 people (32.9%). From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, 2017. From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, 2017. From the results of the chisguare test it can be concluded that knowledge has a relationship with preventive measures for the occurrence of vaginal discharge in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency in 2017. From the results of the chisguare test cross-table attitudes with actions, a p value of 0.000 is obtained. Likewise, attitudes have a relationship with preventive measures for the occurrence of leucorrhoea in the Working Area of ​​the Sindar Raya Health Center, Simalungun Regency, 2017.