Article Per Year (5 Year)
p-Index From 2021 - 2026
0.751
P-Index
This Author published in this journals
All Journal Dentika Dental Journal Eureka Herba Indonesia
Indra Basar Siregar
Unknown Affiliation
Dentistry Medicine & Pharmacology

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Antibacterial Activity Test of Gambas Fruit Extract (Luffa Acutangula (L.) Roxb.) against Bacterial Growth Staphylococcus Aureus In Vitro Stanlee, Elwin; Indra Basar Siregar; Olivia Avriyanti Hanafiah; Isnandar
Eureka Herba Indonesia Vol. 4 No. 3 (2023): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v4i3.85

Abstract

One aspect that needs attention in dental and oral health is bacterial infection, including infections caused by Staphylococcus aureus bacteria. Staphylococcus aureus is a type of gram-positive bacteria that can be found in various parts of the human body, including the skin and nasal mucus. These bacteria usually do not cause problems if they remain within normal limits. However, when Staphylococcus aureus enters the oral cavity or surrounding tissue, it can cause various dental and oral health conditions. Gambas fruit (Luffa acutangula (L.) Roxb.), which is also known as Oyong fruit from the Cucurbitaceae family, has an antibacterial effect. This study aimed to determine the antibacterial activity of the ethanol extract of Gambas fruit (Luffa acutangula (l.) roxb.) on bacterial growth of Staphylococcus aureus in vitro. This type of research is a laboratory experimental design post-test only control group. Research data were analyzed using testone-way ANOVA with post-hoc LSD. The results showed that there was an inhibition diameter at each concentration of Gambas fruit extract. 25% Gambas fruit extract has an average diameter of 10.8 mm, 12.5% Gambas fruit extract has an average diameter of 9.4 mm, 6.25% Gambas fruit extract has an average diameter of 8 mm, l Gambas fruit extract 3.125% has an average diameter of 6.9 mm. Gambas fruit extract has antibacterial properties with a minimum inhibition level of 25% against the bacterial growth of Staphylococcus aureus.
The Effectiveness of Using Jengkol Peel Extract (Pithecellobium lobatum Benth.) in Inhibits Bacterial Growth Staphylococcus aureus In Vitro Indra Basar Siregar; Gostry Aldica Dohude; Rahmi Syaflida Dalimunte; Zata Amani, A Rachma
Eureka Herba Indonesia Vol. 4 No. 3 (2023): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v4i3.87

Abstract

Staphylococcus aureus is aerobic bacteria that are gram-positive and are one of the normal human flora on the skin and mucous membranes. Most infections in the oral cavity are caused by Staphylococcus aureus, which is a normal flora in the oral cavity that can turn into a pathogen if trauma or abrasion occurs on the mucosal surface. Jengkol peel is thought to contain tannin compounds, which have the potential as an anti-inflammatory, anti-diarrheal, antioxidant, treatment of infections of the skin and mouth, and treatment of burns. This study aimed to explore the potential of jengkol peel extract (Pithecellobium lobatum Benth.) as an antibacterial Staphylococcus aureus regularly in vitro. This study is an experimental research in vitro, where as many as 7 treatment groups were used in this study. Positive and negative controls and extract concentrations of 5%-80% were used as the treatment group. Analysis of the average diameter of the inhibition of bacterial growth was carried out using SPSS version 25 software. The potential inhibition of jengkol peel extract was in line with the increase in the concentration of jengkol peel extract. The higher the concentration of jengkol peel extract, the greater the inhibition of bacterial growth. Extract concentration of 20% has a comparable inhibition of bacterial growth control positive. Jengkol peel extract effectively inhibits the growth of Staphylococcus aureus bacteria. Jengkol peel extract concentration of 20% has effectiveness in inhibiting bacterial growth equivalent to 0.2% chlorhexidine in vitro.
Effectiveness Test of Avocado Seed Extract (Persea Americana Mill.) in Inhibiting the Growth of Staphylococcus aureus Bacteria In Vitro Indra Basar Siregar; Isnandar; Rahmi Syaflida Dalimunte; Melenia, Prilisa
Eureka Herba Indonesia Vol. 4 No. 4 (2023): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v4i4.92

Abstract

Staphylococcus aureus can cause several health problems in the oral cavity, including stomatitis, tooth abscess, soft tissue infections, gingivitis, and periodontitis. The exploration of new therapeutic modalities for Staphylococcus aureus infection is urgent. Staphylococcus aureus has developed resistance to many of the antibiotics commonly used to treat bacterial infections. This study aimed to determine the antibacterial effectiveness of avocado seed extract (Persea americana Mill.) in inhibiting bacterial growth of Staphylococcus aureus in vitro. This study is an in vitro study in which 28 petri dishes have been added with 1-2 oses of bacterial culture Staphylococcus aureus and MHA (Mueller Hinton Agar) were used in this study. There were 7 test groups, namely 0.2% chlorhexidine as a positive control (K1), negative control, DMSO (K2), avocado seed extract treatment group 2%, 4%, 6%, 8%, and 10% respectively as K3-K7. Treatment of avocado seed extract with a concentration of 6% has the ability to grow bacteria Staphylococcus aureus better than the bacterial growth ability of the positive control, chlorhexidine. The increase in extract concentration was in line with the increase in the diameter of the bacterial inhibition zone Staphylococcus aureus. Avocado seed extract (Persea americana mill.) showed effectiveness in inhibiting bacterial growth of Staphylococcus aureus in vitro.
Antibacterial Effectiveness of Mackerel (Rastrelliger sp) Fish Oil Emulgel against Staphylococcus aureus Bacteria Using Disk-Diffusion Method. Isnandar; Olivia Avriyanti Hanafiah; Indra Basar Siregar; Salsabila
Dentika: Dental Journal Vol. 28 No. 2 (2025): Dentika: Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/dentika.v28i2.22238

Abstract

Oral health is a major concern in Indonesia, which is caused by bacteria infections in oral cavity.¹ Bacteria such as Staphylococcus play a crucial role in the development of dental diseases, showing the need for improving oral hygiene to prevent infections.² Therefore, this research aimed to evaluate the effectiveness of mackerel fish oil (Rastrelliger sp.) emulgel against Staphylococcus aureus using the disk diffusion method in an in vitro. The investigation was carried out using an experimental laboratory design with a post-test only control group through the Kirby-Bauer disk diffusion method. The samples consisted of various concentrations of mackerel fish oil emulgel (10, 5, 2.5, 1.25, 0.62, and 0.31%). Clinium® gel 1% was used as a positive control, while gel base was served as a negative control. The formation of inhibition zone diameter after 24 hours of incubation was measured in millimeters (mm) using a vernier caliper. The results showed that mackerel fish oil (Rastrelliger sp.) emulgel had antibacterial activity against Staphylococcus aureus. The mean inhibition zone diameters observed at concentrations 10, 5, 2.5, 1.25, 0.62, and 0.31% were 16.99 mm, 13.23 mm, 10.32 mm, 7.18 mm, and 6.23 mm. Mackerel fish oil (Rastrelliger sp.) emulgel showed effective antibacterial activity against Staphylococcus aureus in an in vitro setting.
Co-Authors Dohude, Gostry Aldica Isnandar Melenia, Prilisa Olivia Avriyanti Hanafiah Rahmi Syaflida Dalimunte Salsabila Stanlee, Elwin Zata Amani, A Rachma