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All Journal Jurnal Penelitian Sains Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Multidisciplinary Indonesian Center Journal
Nurfadilasari, Ulfa Mustofa
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Religion Humanities Chemistry Earth & Planetary Sciences Education Mathematics Medicine & Pharmacology Physics Other

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STUDI KUALITATIF PERSEPSI APOTEKER DAN KADER KESEHATAN DALAM PEMANTAUAN OBAT ANTI TUBERKULOSIS DI PUSKESMAS MLATI II SLEMAN Nurfadilasari, Ulfa Mustofa; Perwitasari, Dyah Aryani; Ghozali, MT; Supadmi, Woro
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 1 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i1.1714

Abstract

Background: Long-term treatment of tuberculosis can cause side effects that cause concern for patients. The side effects experienced by patients have an impact on treatment compliance and drug withdrawal. Efforts to control drug withdrawal require the role of pharmacists and cadres in monitoring treatment. Objective: to explore the perception of understanding and actions of pharmacists and cadres in monitoring anti-tuberculosis drugs. Method: This study is qualitative study with a case study approach. Participants selection using purposive sampling namely pharmacists, cadres and TB program holders who are involved in monitoring TB treatment. The number of participants was six people. Results: interview transcripts were analyzed thematically using software QSR NVivo 12. We categorized into three themes : drug side effects, medication adherence, and treatment success. Conclusion: pharmacists' understanding and actions in monitoring TB treatment are good. While the cadres' understanding and actions regarding the side effects of drugs are not good enough, the importance of compliance with taking medication and the success of treatment is good
ASSOCIATION BETWEEN INHALED CORTICOSTEROIDS AND OSTEOPOROSIS: A REVIEW Nurfadilasari, Ulfa Mustofa; Liberitera, Sternatami
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 3 (2025): Vol. 2 No. 3 Edisi Juli 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i3.1241

Abstract

Inhaled corticosteroids (ICS) are commonly prescribed to manage asthma and chronic obstructive pulmonary disease (COPD) due to their local anti-inflammatory effects in the airways. However, prolonged or high-dose ICS use has been associated with systemic adverse effects, including decreased bone mineral density (BMD) and increased risk of osteoporosis. This review aimed to examine the association between ICS use and the risk of osteoporosis or fractures, and to identify modifying factors such as dose, duration, patient age, sex, and type of corticosteroid used. Literature review was conducted using databases including PubMed, Scopus, and Web of Science. Articles were selected using specific inclusion and exclusion criteria. The review focused on original studies published up to March 2025, resulting in 28 relevant articles, of which 6–8 high-quality studies were analyzed in depth. Most studies demonstrated that long-term or high-dose ICS use is associated with decreased BMD and increased risk of fractures, especially in elderly COPD patients. The greatest risk was linked to fluticasone and budesonide at doses ≥500 µg/day. Some studies found neutral or even protective effects in specific subgroups, indicating population-dependent variability. Meta-analyses revealed conflicting results due to heterogeneity in populations and methodologies. High-dose and long-term ICS use may increase the risk of osteoporosis. Clinicians should consider individualized risk assessments and adopt strategies such as using the lowest effective dose, monitoring BMD, and providing calcium and vitamin D supplementation in at-risk populations.
Optimalisasi Penggunaan Mikronutrisi dalam Meningkatkan Luaran Klinis dan Menurunkan Durasi Rawat Inap pada Pasien dengan Infeksi Liberitera, Sternatami; Nurfadilasari, Ulfa Mustofa
Jurnal Penelitian Sains Vol 27, No 3 (2025)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56064/jps.v27i3.1218

Abstract

Durasi rawat inap yang berkepanjangan pada pasien dengan penyakit infeksi dapat meningkatkan risiko komplikasi, memperburuk komorbiditas, menambah beban biaya, dan menurunkan kualitas hidup secara signifikan. Mikronutrisi telah dilaporkan memiliki peran penting dalam mempercepat pemulihan klinis melalui berbagai mekanisme biologis seperti modulasi sistem imun, pengurangan respon inflamasi, penurunan stres oksidatif, serta percepatan regenerasi jaringan epitel yang rusak. Studi ini bertujuan untuk mengkaji hubungan antara penggunaan mikronutrien dan luaran klinis pasien infeksi juga terhadap durasi rawat inap. Penelusuran literatur dilakukan melalui database elektronik PubMed, Scopus, Cochrane, dan Embase pada artikel yang diterbitkan dalam 10 tahun terakhir menggunakan kata kunci relevan. Sebanyak 13 artikel yang memenuhi kriteria inklusi dianalisis secara naratif. Hasil telaah menunjukkan bahwa suplementasi mikronutrien seperti zinc, vitamin A, C, D, dan selenium dapat memberikan manfaat klinis bermakna, termasuk pemendekan lama rawat inap. Mikronutrisi tidak hanya bertindak sebagai nutrisi pendukung, tetapi juga sebagai bagian integral dari terapi suportif pada pasien infeksi. Strategi intervensi  dapat dilakukan dengan penggunaan mikronutrien yang optimal pada praktik farmasi klinis untuk meningkatkan efisiensi perawatan dan mempercepat pemulihan pasien. 
Co-Authors Dyah Aryani Perwitasari Muhammad Thesa Ghozali Sternatami Liberitera Woro Supadmi