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Analysis of Klebsiella Pneumonia and Resistance Genes Coding and Carbapenemase Production in National Referral Hospital Wastewater Simanjuntak, Glory Gelarich; Karuniawati, Anis; Saharman, Yulia Rosa; Muziasari, Windi
Jurnal Kesehatan Vol 14 No 3 (2023): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v14i3.4147

Abstract

Hospitals, as a source of transmission and spread of bacteria carrying antibiotic-resistant genes (ARGs) as well as a high source of antibiotic compounds, are a significant reservoir of antibiotic-resistant gene transfer that causes bacteria to develop multidrug resistance (MDR). Klebsiella pneumonia is a bacterium often found in wastewater with a high level of Extended Spectrum β-lactamase (ESBL) and carbapenemase resistance. This study aimed to determine Klebsiella pneumonia and resistance genes encoding ESBL and carbapenemase in hospital wastewater to obtain primary Antimicrobial Resistance (AMR) data in the environment, which was first conducted in Indonesia. The resistance gene detection method was developed using High Throughput Real-Time and conventional Real-Time (HT-RT PCR). The data obtained were relative abundance and copy number. The results showed that blaTEM and blaNDM were the highest ARGs. Conventional Real-Time PCR results showed better sensitivity in detecting K. pneumoniae and ARGs than HT-RT PCR. The detection of K. pneumoniae and ARGs in RSCM wastewater in Indonesia indicates the need to improve the handling of RSCM WWTP to monitor the number of microbial resistances to antibiotics.
Damage to The Surface Of Children's Teeth Due To The Impact Of Milk Formula Giving Patterns Over A Long Period Of Time Due To Acid Production In The Oral Cavity (Caries) Musaidah, Musaidah; P, Nur Triningtias; Simanjuntak, Glory Gelarich; Rahmat, Rezqiqah Aulia
International Journal of Health Sciences Vol. 3 No. 2 (2025): IJHS : International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v3i2.668

Abstract

Formula milk is milk produced by industry. For needs intake nutrition in the system body child which contain carbohydrate like sucrose and lactose which can result in caries teeth in children age preschool. Dental caries is one of disturbance health teeth that experience calcification so that tooth become porous, perforated even broken. Research Objectives this is for know influence consumption of formula milk against caries teeth. Research this use type study literature study, where method literature study looking for data used originate from textbooks, journals, articles scientific, literature review containing about Influence Consumption Formula Milk Against Caries Teeth. Research results that consumption of formula milk has an effect to caries tooth child age preschool. Content carbohydrate like sucrose and lactose can cause caries teeth and if too often consuming formula milk then level severity caries tooth the more high. Research conclusion this is factor main the occurrence caries in children age preschool is with consume food and drink cariogenic.
Kegiatan Pengabdian Masyarakat: Penyuluhan Dan Edukasi Tentang Pencegahan Diabetes Melitus Simanjuntak, Glory Gelarich
Sahabat Sosial: Jurnal Pengabdian Masyarakat Vol. 3 No. 3 (2025): Sahabat Sosial: Jurnal Pengabdian Masyarakat (Juni)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/sosisabdimas.v3i3.745

Abstract

Diabetes Mellitus (DM) is a non-communicable disease that is a global health problem and a leading cause of morbidity and mortality. Data from the International Diabetes Federation (IDF) in 2021 shows that Indonesia ranks fifth in the world for the number of diabetes sufferers. Diabetes prevention can be achieved through promotive and preventive interventions, one of which is providing community outreach and education. This Community Service (CSP) activity aims to increase public knowledge and awareness about the importance of diabetes prevention through a healthy lifestyle, early detection, and risk factor management. The activity method included interactive lectures, question-and-answer discussions, and the distribution of educational leaflets to 50 participants, consisting of productive-age and elderly residents in the activity area. Knowledge evaluation was conducted using pre- and post-tests. The results of the activity showed a 50% increase in participants' knowledge (from an average of 30% before the outreach to 80% after the outreach). Furthermore, participants demonstrated a high level of interest in adopting a healthy diet, regular exercise, and regular blood sugar checks. This activity successfully increased community understanding of diabetes prevention and can be developed into a sustainable program integrated with community health center programs and health cadres in the area.
Formulasi Dan Uji Stabilitas Sediaan Krim Tabir Surya Dari Ekstrak Teh Hijau (Camellia Sinensis) Simanjuntak, Glory Gelarich; Pramono, Edi
Barongko: Jurnal Ilmu Kesehatan Vol. 3 No. 3 (2025): Barongko : Jurnal Ilmu Kesehatan (Juli)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/bajik.v3i3.776

Abstract

Excessive exposure to ultraviolet (UV) light can cause various skin problems, such as premature aging, hyperpigmentation, erythema, and even skin cancer. The use of sunscreen is a primary preventative measure to reduce these risks. However, most commercial sunscreen products contain synthetic chemicals that can cause irritation or other side effects on sensitive skin. Therefore, a safer and more environmentally friendly natural-based sunscreen preparation is needed. This study aimed to formulate a sunscreen cream based on green tea (Camellia sinensis) extract and evaluate its physical stability and effectiveness in absorbing UV light. Green tea extract was obtained through a maceration method using 70% ethanol, then formulated into a cream preparation with varying concentrations of 5%, 10%, and 15%. The evaluation included organoleptic tests, pH, homogeneity, viscosity, spreadability, temperature stability, and in vitro Sun Protection Factor (SPF) calculation using UV-Vis spectrophotometry. The results showed that all formulas exhibited fairly good physical stability during storage. The formula with a 10% extract concentration showed the most optimal results, with an SPF of 13.2, which is categorized as moderate protection, and good physical stability. This study concludes that green tea extract has potential as a natural active ingredient in sunscreen preparations, especially at a concentration of 10%.