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All Journal Berkala Kedokteran Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
Nur’amin, Hendra Wana
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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PERBANDINGAN EFEKTIVITAS NATRIUM DIKLOFENAK DAN MELOKSIKAM PADA DERAJAT KEPARAHAN PASIEN PEREMPUAN DENGAN OSTEOARTRITIS LUTUT Aulia, Ahmad Candra; Pambudi, Pagan; Nur’amin, Hendra Wana; Noor, Zairin; Qamariah, Nur
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13176

Abstract

Abstract: Osteoarthritis is a disease characterized by degeneration of cartilage an bone underneath in the joints and excessive bone growth. This tissue damage eventually causes pain and joint stiffness. Non-Steroidal Anti-Inflamatory Drugs (NSAIDs) are usually considered the first line intreatment of osteoarthritis in the treatment of osteoarthritis. NSAIDs that are often used in the treatment are sodium dicofenac and meloxicam. This study aims to compare the effectiveness of sodium diclofenac and meloxicam in the severity of female subject with knee osteoarthritis in RSUD Dr. H. M Ansari Saleh Banjarmasin. The method used in this study is analytical observational with the cohort prospective research design. The sample in this study was chosen in a simple random sampling way with a total of 20 subject, 10 people received sodium diclofenac therapy and 10 people received meloxicam therapy, which would then be analyzed using T test. There is a significal difference in the lequesne index before and after administration of sodium diclofenac (p = 0,008) and meloxicam (p = 0,038). There is no significant difference between sodium diclofenac therapy compared to meloxicam (p = 0,55). Keywords: knee osteoartritis, sodium diclofenac, meloxicam Abstrak: Osteoartritis adalah penyakit sendi yang ditandai dengan degenerasi tulang rawan dan tulang dibawahnya di dalam sendi serta pertumbuhan tulang yang berlebihan. Kerusakan jaringan ini akhirnya menyebabkan nyeri dan kekakuan sendi. Non-Steroidal Anti-Inflamatory Drugs (NSAID) biasanya dianggap sebagai lini pertama dalam pengobatan osteoartritis. NSAID yang sering digunakan dalam pengobatan osteoartritis adalah natrium diklofenak dan meloksikam. Penelitian ini bertujuan untuk membandingkan efektivitas natrium diklofenak dan meloksikam pada derajat keparahan subyek perempuan dengan osteoartritis lutut di RSUD dr H. M. Ansari Saleh Banjarmasin. Metode yang digunakan dalam peneltian ini yaitu observasional analitik dengan desain penelitian cohort prospective. Sampel dalam penelitian ini dipilih dengan cara simple random sampling dengan total subyek sejumlah 20 orang, 10 orang mendapatkan terapi natrium diklofenak dan 10 orang mendapatkan terapi meloksikam, yang kemudian akan dianalisis dengan menggunakan uji T test. Terdapat perbedaan bermakna pada indeks lequesne sebelum dan sesudah pemberian natrium diklofenak (p = 0,008) dan meloksikam (p = 0,038). Tidak terdapat perbedaan signifikan antara terapi natrium diklofenak dibandingkan meloksikam (p = 0,55) Kata-kata kunci: osteoartritis lutut, natrium diklofenak, meloksikam
GAMBARAN PENGGUNAAN ANTIVIRUS PADA PASIEN COVID-19 DI RUANG ICU RSUD ULIN BANJARMASIN Nirmala, Anisa Feby Insan; Rahmiati, Rahmiati; Nur’Amin, Hendra Wana; Nurrasyidah, Ira; Yasmina, Alfi
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11445

Abstract

Antivirus is one of the main therapies for COVID-19. Patients with COVID-19 who need to be transferred to the ICU are those who are seriously ill to critically ill. The purpose of this study was to describe the use of antivirals in COVID-19 patients in the ICU room at Ulin Hospital, Banjarmasin. This study was necessary because no antiviral has been proven effective and specific yet for COVID-19 therapy, the high rate of spread of COVID-19 over the last two years, the large number of cases requiring ICU care, the risk of using antivirals in COVID-19 patients who have certain comorbidities, and this study had never been done before. This study used a descriptive observational study design with ICU patients aged >18 years who were given COVID-19 antiviral therapy with complete electronic data records and/or medical records in the 2020-2021 period. This study found 59 subjects with antivirals used included remdesevir (52.54%), lopinavir+ritonavir (22.03%), favipiravir (15.25%), and oseltamivir (10.16%). Most of the patients were 46-65 years and used remdesevir (50%). Based on gender, both male and female patients used remdesevir (52.54%) as the antiviral. The most common comorbidities were hypertension with remdesevir (42.30%). Based on the duration of hospitalization, the longest duration of hospitalization was remdesevir with an average of 8.74 days.
The Effect of Wetland Geography on the Prevalence of Diabetes Mellitus in South Kalimantan Fajari, Nanang Miftah; Nur’amin, Hendra Wana
Berkala Kedokteran Vol 19, No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i2.17387

Abstract

Diabetes mellitus (DM) is a high-burden disease in Indonesia especially in South Kalimantan Province. South Kalimantan province lies in mostly wetlands areas. Identification of risk factors related to DM is necessary to prevent the disease. We conducted this study to assess the prevalence of DM in the South Kalimantan people, the impact of a wetlands area on DM prevalence, and other significant risk factors. A cross-sectional study approach was used to identify significant risk factors. We used adjusted multiple logistic regression to assess the association between risk factors and DM prevalence. There were 4612 subjects more than 18 years old in this study with 6.5% of them diagnosed as DM. Most of the subjects live in wetlands area (79.1%) and most of them >40 years old. Several important risk factors associated with DM were identified. Subjects in wetlands have a lower risk of DM compared to non-wetlands area (OR 0.73, CI 95%; 0.43-0.71, p<0.001). Age >40 years old increase the risk of DM (OR 2.24, CI 95 % 1.61-3.10, p<0.001), hypertension (OR 1.65, CI 95% 1.23-2.21, p<0,001), waist circumference >90 cm (OR 2.12, CI 95%. p<0.001), cholesterol level (>200 mg/dl) with DM prevalence (OR 1.38, CI 95% 1.02-1.87, p<0.04) and family history of DM (OR 10.28, CI 95% 7.67-13.76, p<0.001). This study found that wetlands areas may reduce the DM prevalence and other risk factors may increase the prevalence of DM. Further research is necessary to establish the relationship between wetlands area and DM.
KORELASI LINGKAR PERUT DENGAN TINGKAT KEPARAHAN OSTEOARTRITIS LUTUT PADA PASIEN PEREMPUAN DI RSUD DR. H. MOCH. ANSARI SALEH Mujiningtyas, Tsalsa Rohmatul Jannah; Pambudi, Pagan; Nur’amin, Hendra Wana; Noor, Zairin; Qamariah, Nur
Homeostasis Vol 7, No 3 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i3.14609

Abstract

Abstract: Osteoartritis (OA) is a chronic inflammatory disease of the synovial joints, accompanied by damage to the joint cartilage and bones. Abdominal circumference measurements are carried out to determine abdominal or central obesity. Several studies show that the larger the abdominal circumference, the higher the severity of OA. This research is an analytical observational study with a cross-sectional research design. The sample in this study was selected using simple random sampling with a total of 30 respondents who would then be analyzed using the Spearman test. Abdominal circumference profile data showed that 23 patients (76,67%) had abdominal circumference >80 cm and 7 patients (23,33%) had abdominal circumference ≤80 cm. Data on the severity profile of knee osteoartritis showed that 17 patients (56,67%) had grade 1 knee OA, 7patients (23,33%) had grade 2, 5 patients (16,67%) had grade 3, and 1 patients (3,33%) had grade 4. The results of Spearman’s correlation analysis showed that there was no significant correlation between abdominal circumference and the severity of knee osteoartritis in female patients at RSUD dr. H. Moch. Ansari Saleh (p=0,563). Keywords: knee osteoartritis, abdominal circumference, female Abstrak: Osteoartritis (OA) adalah penyakit inflamasi kronik pada sendi sinovial, disertai kerusakan pada kartilago sendi dan tulang. Pengukuran lingkar perut dilakukan untuk menentukan obesitas abdomen atau sentral. Beberapa penelitian menunjukkan bahwa semakin besar lingkar perut maka semakin tinggi tingkat keparahan OA. Penelitian ini merupakan penelitian observasional analitik dengan desain penelitian cross-sectional. Sampel dalam penelitian ini dipilih dengan cara simple random sampling dengan total responden sejumlah 30 orang yang kemudian akan dianalisis dengan menggunakan uji Spearman. Data profil lingkat perut menunjukkan sebanyak 23 pasien (76,67%) memiliki lingkar perut >80 cm dan sebanyak 7 pasien (23,33%) memiliki lingkar perut ≤80 cm. Data profil tingkat keparahan osteoartritis lutut menunjukkan sebanyak 17 pasien (56,67%) mengalami OA lutut grade 1, grade 2 sebanyak 7 pasien (23,33%), grade 3 sebanyak 5 pasien (16,67%), dan grade 4 sebanyak 1 pasien (3,33%). Hasil analisis korelasi Spearman menunjukkan tidak terdapat korelasi bermakna antara lingkar perut dengan tingkat keparahan osteoartritis lutut pada pasien perempuan di RSUD dr. H. Moch. Ansari Saleh (p=0,563). Kata-kata kunci: osteoartritis lutut, lingkar perut, perempuan
PROFIL PASIEN HIV DI POLIKLINIK VCT RSUD ULIN BANJARMASIN TAHUN 2021-2022 Darwis, Muhammad Wisnu Adi; Zaitun, Nani; Rahmiati, Rahmiati; Nur’amin, Hendra Wana; Hayatie, Lisda
Homeostasis Vol 7, No 3 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i3.14536

Abstract

Abstract: Human Immunodeficiency Virus is a major threat and problem in the health sector. The aim of the study was to describe the profile of HIV patients at the VCT Polyclinic of Ulin Banjarmasin Hospital in 2021-2022. The research method is descriptive observational using secondary data from the VCT Polyclinic registration books and PDE. The results showed that there were 147 HIV cases with the highest cases in 2022 totaling 75 patients (51%). Based on variables, the most cases in 2021 were age groups 17-25 and 26-35 years (26%), male gender (72%), Banjarmasin domicile (56%), working status (44%), secondary education level (47%), key population MSM (22%), heterosexual transmission (26%), clinical stages 3 and 4 (24%), opportunistic tuberculosis infection (15%), first line therapy regimen (93%), and CD4 count <100 cells/mm3 (32%). Whereas in 2022, the highest number of cases were in the age group of 26-35 years (40%), male gender (67%), Banjarmasin domicile (59%), working and non-working status (36%), no school education (27%), key population of MSM (34%), homosexual transmission (40%), clinical stage 4 (45%), opportunistic tuberculosis infection (15%), first line therapy regimen (97%), and CD4 count <100 cells/mm3 (27%). The number of cases of opportunistic infections based on the highest CD4 count was tuberculosis with 7 patients in 2021 and 12 patients in 2022 with the highest CD4 count for the appearance of opportunistic infections, namely <100 cells/mm3 (74%).  Keywords: HIV, patients profile, opportunistic infection, key populations, Banjarmasin. Abstrak: Human Immunodeficiency Virus merupakan ancaman dan permasalahan utama bidang kesehatan. Tujuan penelitian adalah mendeskripsikan profil pasien HIV di Poliklinik VCT RSUD Ulin Banjarmasin tahun 2021-2022. Metode penelitian yaitu observasional deskriptif menggunakan data sekunder dari buku registrasi Poliklinik VCT dan PDE. Hasil penelitian menunjukkan kasus HIV sejumlah 147 pasien dengan kasus tertinggi tahun 2022 sejumlah 75 pasien (51%). Berdasarkan variabel, kasus terbanyak tahun 2021 yaitu kelompok umur 17-25 dan 26-35 tahun (26%), jenis kelamin laki-laki (72%), domisili Banjarmasin (56%), status bekerja (44%), tingkat pendidikan menengah (47%), populasi kunci LSL (22%), penularan heteroseksual (26%), stadium klinis 3 dan 4 (24%), infeksi oportunistik tuberkulosis (15%), regimen lini terapi pertama (93%), dan jumlah CD4 <100 sel/mm3 (32%). Sedangkan tahun 2022 kasus terbanyak yaitu kelompok umur 26-35 tahun (40%), jenis kelamin laki-laki (67%), domisili Banjarmasin (59%), status bekerja dan tidak bekerja (36%), pendidikan tidak sekolah (27%), populasi kunci LSL (34%), penularan homoseksual (40%), stadium klinis 4 (45%), infeksi oportunistik tuberkulosis (15%), regimen lini terapi pertama (97%), dan jumlah CD4 <100 sel/mm3 (27%). Jumlah kasus infeksi oportunistik berdasarkan jumlah CD4 terbanyak yaitu tuberkulosis sebanyak 7 pasien di tahun 2021 dan 12 pasien di tahun 2022 dengan jumlah CD4 terbanyak munculnya infeksi oportunistik yaitu <100 sel/mm3 (74%). Kata-kata kunci: HIV, profil pasien, infeksi oportunistik, populasi kunci, Banjarmasin.
Co-Authors Alfi Yasmina Aulia, Ahmad Candra Darwis, Muhammad Wisnu Adi Ira Nurrasyidah Lisda Hayatie, Lisda Mujiningtyas, Tsalsa Rohmatul Jannah Nanang Miftah Fajari Nirmala, Anisa Feby Insan Nur Qamariah Pagan Pambudi Rahmiati Rahmiati Zairin Noor Zaitun, Nani