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All Journal Medical Journal of Indonesia Berkala Kedokteran CRJIM (Clinical and Research Journal in Internal Medicine) Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
Nanang Miftah Fajari
University Of Lambung Mangkurat
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Correlation of Ankle - Brachial Index (ABI) and Low - Density Lipoprotein (LDL) with Diabetic Foot Severity Degree Muhammad Ghaly Maulana; Nanang Miftah Fajari; Dewi Indah Noviana Pratiwi
Berkala Kedokteran Vol 16, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.262 KB) | DOI: 10.20527/jbk.v16i1.8205

Abstract

Abstract: Diabetic foot is a complication of diabetes mellitus which is characterized by ulceration in the legs. The severity of the diabetic foot can be determined by the Wagner-Meggit system which in this study uses 5 categories namely degrees 1 - 5 degrees. ABI (Ankle-Brachial Index) is an evaluation of peripheral arterial disease in diabetic foot patients. LDL is the main factor of atherosclerosis which causes macrovascular disorders in diabetic foot. The purpose of this study was to determine the correlation between ABI and LDL on the severity of diabetic foot based on the Wagner-Meggit classification. The method used is observational analytic with cross sectional approach. A total of 35 samples were obtained by consecutive sampling. Data analysis was performed using the Spearman test and logistic regression. A significant correlation was obtained between ABI and the severity of diabetic foot (p = 0.06; r = -0.424), there was no correlation between LDL and the severity of diabetic foot (p = 0.09; r = -0.395). The results of logistic regression analysis found no correlation between ABI (p = 0.163; OR = 0.008) and LDL (p = 0.69; OR = 0.984) with the severity of the diabetic foot. Obtained Negelkerke R Square value of 0.095. Keywords: Diabetic foot, ABI, LDL, Wagner-Meggit classification
Korelasi Rasio Neutrofil-Limfosit terhadap Derajat Keparahan Kaki Diabetes Marcellinus Anthony Raharjo; Dewi Indah Noviana Pratiwi; Nanang Miftah Fajari Fajari
Homeostasis Vol 3, No 3 (2020)
Publisher : Homeostasis

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Abstract

Abstract: Diabetic foot is an advanced complication of diabetes which has multifactorial causes such as neuropathy and peripheral arterial disease. The severity of diabetic foot based on Wagner-Meggit is 6 namely wagner degree 0-5 with the lowest wagner degree 0 to wagner degree 5 which is the most severe, in this study the severity of diabetes foot based on Wagner-Meggit used is degrees 1-5. The neutrophil-lymphocyte ratio is an inflammatory marker that can be obtained by comparing neutrophils to lymphocytes in a patient's leukocyte count. The purpose of this study was to determine the correlation between the ratio of neutrophils-lymphocytes to the severity of diabetes foot using the severity of Wagner. The research method used was observational analytic with cross sectional approach in a group of diabetic foot patients with prospective data collection. Data analysis using the Spearman test. The results obtained 28 samples that fit the inclusion and exclusion criteria.. No significant correlation was found between neutrophils to lymphocytes ratio to the severity of the diabetic foot (p = 0.14). Keywords: Diabetic foot, degree of severity Wagner-Meggit, neutrophil-lymphocyte ratio Abstrak: Kaki diabetes merupakan komplikasi lanjut dari penyakit diabetes yang memiliki penyebab multifaktor seperti neuropati dan penyakit arteri perifer. Derajat keparahan kaki diabetes berdasarkan Wagner-Meggit terdapat 6 yaitu derajat wagner 0-5 dengan derajat wagner 0 yang paling ringan sampai derajat wagner 5 yang paling parah, pada penelitian ini derajat keparahan kaki diabetes berdasarkan Wagner-Meggit yang digunakan adalah derajat 1-5. Rasio neutrofil-limfosit adalah marker inflamasi yang bisa didapatkan dengan membandingkan neutrofil dengan limfosit pada hitung leukosit pasien. Tujuan dari penelitian ini adalah mengetahui korelasi antara rasio neutrofil-limfosit terhadap tingkat keparahan kaki diabetes menggunakan derajat keparahan Wagner. Metode penelitian yang digunakan adalah observasional analitik dengan pendekatan cross sectional pada kelompok pasien kaki diabetes dengan pengambilan data secara prospektif. Analisis data menggunakan uji Spearman. Hasil penelitian didapatkan 28 sampel yang sesuai dengan kriteria inklusi dan eksklusi.. Tidak didapatkan korelasi yang bermakna antara rasio neutrofil-limfosit dengan derajat keparahan kaki diabetes (p = 0,14). Kata-kata kunci: Kaki diabetes. derajat keparahan Wagner-Meggit, Rasio neutrofil-limfosit
Profil Penggunaan Insulin pada Pasien Diabetes Melitus Rawat Inap yang Mengalami Hipoglikemia Firzatullah Ega Radyastra; Nanang Miftah Fajari; Franciscus Xaverius Hendriyono
Homeostasis Vol 4, No 1 (2021)
Publisher : Homeostasis

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Abstract

Abstract: One of the factors that can cause hypoglycemia in diabetes mellitus patients who are hospitalized is the use of insulin therapy.The purpose of this study was to determine the profile of insulin use in inpatient DM patients who experienced hypoglycemia in the subspecialty clinic in the endocrine division of the Ratu Zalecha Martapura Regional Hospital. This research is descriptive with a cross-sectional approach. The technique of taking the subject uses a total sampling technique. There were 30 DM patients who experienced hypoglycemia with insulin therapy. The results showed that the age group that experienced the most hypoglycemia was 46 - 55 years (40%), had diabetes for ≥ 1 year (73.3%), and the most widely used regimen was basal - bolus (70%) then total the daily dose used at the baseline was 11.17 ± 4.47 units and the bolus portion was 20.83 ± 8.83 units. The conclusion of this study is that the most frequently used insulin regimen in inpatients with hypoglycemia is basal - bolus. Keyword:hypoglycemia, diabetes mellitus, insulin, inpatient, hospitalized. Abstrak: Salah satu faktor yang dapat menyebabkan kejadian hipoglikemia pada pasien DM rawat inap di rumah sakit adalah penggunaan terapi insulin. Tujuan penelitian ini untuk mengetahui profil penggunaan insulin pada pasien DM rawat inap yang mengalami hipoglikemia di Poli subspesialis penyakit dalam divisi endokrin RSUD Ratu Zalecha Martapura. Penelitian ini bersifat deskriptif dengan pendekatan cross-sectional. Teknik pengambilan subjek menggunakan teknik total sampling. Didapatkan 30 subjek pasien DM yang mengalami hipoglikemia dengan terapi insulin. Hasil penelitian menunjukkan kelompok umur yang paling banyak mengalami hipoglikemia adalah 46 – 55 tahun (40%), telah mengidap DM selama ≥ 1 tahun (73,3%), dan regimen yang paling banyak digunakan adalah basal – bolus (70%) lalu total dosis harian yang digunakan pada bagian basalnya 11.17 ± 4,47 unit dan bagian bolusnya 20,83 ± 8,83 unit. Kesimpulan penelitian ini adalah regimen insulin yang paling sering digunakan pada pasien DM rawat inap yang mengalami hipoglikemia adalah basal – bolus.  Kata - kata kunci: hipoglikemia, diabetes melitus, insulin, rawat inap, rumah sakit.Abstract: One of the factors that can cause hypoglycemia in diabetes mellitus patients who are hospitalized is the use of insulin therapy. The purpose of this study was to determine the profile of insulin use in inpatient DM patients who experienced hypoglycemia in the subspecialty clinic in the endocrine division of the Ratu Zalecha Martapura Regional Hospital. This research is descriptive with a cross-sectional approach. The technique of taking the subject uses a total sampling technique. There were 30 DM patients who experienced hypoglycemia with insulin therapy. The results showed that the age group that experienced the most hypoglycemia was 46 - 55 years (40%), had diabetes for ≥ 1 year (73.3%), and the most widely used regimen was basal - bolus (70%) then total the daily dose used at the baseline was 11.17 ± 4.47 units and the bolus portion was 20.83 ± 8.83 units. The conclusion of this study is that the most frequently used insulin regimen in inpatients with hypoglycemia is basal - bolus. Keyword:hypoglycemia, diabetes mellitus, insulin, inpatient, hospitalized. Abstrak: Salah satu faktor yang dapat menyebabkan kejadian hipoglikemia pada pasien DM rawat inap di rumah sakit adalah penggunaan terapi insulin. Tujuan penelitian ini untuk mengetahui profil penggunaan insulin pada pasien DM rawat inap yang mengalami hipoglikemia di Poli subspesialis penyakit dalam divisi endokrin RSUD Ratu Zalecha Martapura. Penelitian ini bersifat deskriptif dengan pendekatan cross-sectional. Teknik pengambilan subjek menggunakan teknik total sampling. Didapatkan 30 subjek pasien DM yang mengalami hipoglikemia dengan terapi insulin. Hasil penelitian menunjukkan kelompok umur yang paling banyak mengalami hipoglikemia adalah 46 – 55 tahun (40%), telah mengidap DM selama ≥ 1 tahun (73,3%), dan regimen yang paling banyak digunakan adalah basal – bolus (70%) lalu total dosis harian yang digunakan pada bagian basalnya 11.17 ± 4,47 unit dan bagian bolusnya 20,83 ± 8,83 unit. Kesimpulan penelitian ini adalah regimen insulin yang paling sering digunakan pada pasien DM rawat inap yang mengalami hipoglikemia adalah basal – bolus.  Kata - kata kunci: hipoglikemia, diabetes melitus, insulin, rawat inap, rumah sakit.
Korelasi Kadar Albumin Serum terhadap Derajat Keparahan Kaki Diabetes Jeremy Eckhart S Parhusip; Dewi Indah Noviana Pratiwi; Nanang Miftah Fajari Fajari
Homeostasis Vol 3, No 2 (2020)
Publisher : Homeostasis

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Abstract

Abstract: Diabetic foot is ulceration neuropathy and peripheral vascular disease in the limbs. Wounds that do not heal in diabetic foot conditions cause plasma leakage and will decrease serum albumin level. Serum albumin is a protein that can describe the severity of diabetic foot. The severity of the diabetic foot is measured based on the Wagner-Meggit classification. The purpose of this study was to determine correlation between serum albumin levels and the severity of diabetic foot in diabetic foot ulcer polyclinic at Ulin Hospital Banjarmasin. This research was an analytic observational with cross-sectional approach. 33 samples were obtained by purposive sampling. Average levels Subject serum albumin was 2.88 ± 0.69 g/dL. The analysis using the Spearman correlation test showed a correlation between serum albumin levels and the severity of diabetes feet. The conclusion is, there was a significant correlation of serum albumin levels with the severity of diabetes foot, the direction of the correlation is negative with a moderate strength correlation in diabetic foot ulcer polyclinic at Ulin Hospital Banjarmasin. (p <0.001; r = -0.582) Keywords: Diabetic foot, albumin serum level, Wagner-Meggit classification. Abstrak: Kaki diabetes adalah ulserasi dan destruksi jaringan ikat dengan neuropati dan penyakit vaskuler perifer pada tungkai. Luka yang tidak sembuh pada kondisi kaki diabetes menyebabkan kebocoran plasma, sehingga albumin serum mengalami penurunan. Albumin serum adalah protein yang dapat menggambarkan keparahan dari kaki diabetes. Derajat keparahan kaki diabetes diukur menggunakan klasifikasi Wagner-Meggit. Tujuan penelitian ini untuk mengetahui korelasi kadar albumin serum terhadap derajat keparahan kaki diabetes di poliklinik kaki diabetes RSUD Ulin Banjarmasin. Penelitian ini bersifat observasional analitik dan pendekatan cross-sectional. Sebanyak 33 sampel didapat secara purposive sampling. Rerata kadar albumin serum subjek 2,88 ± 0,69 g/dL. Analisis bivariat menggunakan uji korelasi Spearman menunjukan adanya korelasi. Kesimpulan terdapat korelasi bermakna kadar albumin serum dengan derajat keparahan kaki diabetes, arah korelasi negatif dengan kekuatan sedang pada kaki diabetes di poliklinik kaki diabetes RSUD Ulin Banjarmasin. (p< 0,001; r = -0,582). Kata kunci: Kaki diabetes, albumin serum, klasifikasi Wagner-Meggit.
Literature Review: Hubungan Kadar Trigliserida terhadap Kejadian Kaki Diabetes Marwah Hulfah; Fauzia Noor Liani; Dewi Indah Noviana Pratiwi; Nanang Miftah Fajari; Azma Rosida
Homeostasis Vol 4, No 3 (2021)
Publisher : Homeostasis

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Abstract

Abstract: The increasing number of people with diabetes mellitus each year, diabetic foot is complication of diabetes mellitus which is characterized by the presence of foot ulceration. High triglycerides levels are a factor that triggers atherosclerosis which causes mocrova scular disorders in the diabetic foot.  This literature review was written with the aim of summarizing and knowing the relationship of triglycerides levels to the severity of diabetic foot. This writing is done by analyzing library sources, namely related journals obtained through medical journal databases, namely PubMed, Science Direct and Google Scholar. The included journals were published in 2013-2018. The method in this study uses systematic literature review on 5 related studies. Results 1 in literature get significant results on triglycerides level with a value of p =0.011. High triglycerides levels have been linked to the incidence of diabetic foot ulcer. Keywords: triglycerides, diabetic foot, lipid profile. Abstrak: semakin meningkatnya angka penderita diabetes mellitus tiap tahunnya, kaki diabetik merupakan komplikasi dari penyakit diabetes mellitus yang ditandai dengan adanya ulserasi pada kaki. Tinggi nya kadar trigliserida merupakan faktor yang memicu terjadinya aterosklerosis y ang menyebabkan gangguan makrovaskular pada kaki diabetik. Liternture review ini ditulis dengan tujuan untuk merangkum dan mengetahui hubungan kadar trigliserida terhadap keparahan kaki diabetik. Penulisan ini dilakukan dengan menganalisis sumber pustaka yaitu berupa jurnal terkait yang didapatkan melalui database jurnal kedokteran, yaitu PubMed, Science Direct dan Gongle Scholnr. Jurnal yang disertakan dipublikasikan pada tahun 2013-201d. Metode pada penelitian ini menggunakan systematic literature review terhadap 5 penelitian yang berkaitan. Hasil yang didapat 1 literritiire dengan kadar trigliserida nilai p= 0,011 . Kadar trigliserida yang tinggi memiliki hubungan pada kejadian kaki diabetis. Kata-kata kunci:  trigliserida, kaki diabetik, profil lipid.
Literatur Review: Pengaruh Diabetes Mellitus terhadap Konversi Apusan Sputum setelah Fase Intensif pada Pasien Tuberkulosis Paru Muhammad Ilham Fadillah; Ira Nurrasyidah; Nanang Miftah Fajari
Homeostasis Vol 4, No 1 (2021)
Publisher : Homeostasis

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Abstract

Abstract: The relationship between diabetes mellitus (DM) and tuberculosis (TB) infection has been reported in various studies. Hyperglycemia in DM will increase oxidative stress which will decrease the host's response to Mycobacterium tuberculosis (M. tb) infection. Poor glycemic control is associated with reduced treatment outcome in TB-DM patients. The sputum smear conversion in pulmonary TB patients is the most important indicator in evaluating the effectiveness of a given treatment. About 95% of converted sputum smears occurred after the intensive phase of ATD therapy. Time delay appears as an indication of treatment failure. This literature review aims to see the effect of DM on sputum smear conversion after intensive phase therapy in pulmonary tuberculosis patients. This study method is in the form of a review of the study of the effect of DM on the conversion of pulmonary tuberculosis sputum smear during the last 10 years (2010 – 2020).  The results of this literature review show that DM affects the delay in sputum smear conversion after intensive phase therapy. This effect is more significant in DM patients with poor glycemic control. Keywords: diabetes mellitus, tuberculosis, smear conversion Abstak: Hubungan antara diabetes mellitus (DM) dengan infeksi tuberkulosis (TB) telah dilaporkan pada berbagai studi. Kondisi hiperglikemia pada DM akan meningkatkan stres oksidatif yang akan menyebabkan penurunan respons host terhadap infeksi Mycobacterium tuberculosis (M. tb). Kontrol glikemik yang buruk dikaitkan dengan penurunan hasil pengobatan pada pasien TB-DM. Konversi apusan sputum pada pasien TB paru merupakan indikator yang paling penting dalam evaluasi efektifitas pengobatan yang diberikan.Sekitar 95% konversi apusan sputum terjadi setelah terapi OAT fase intensif. Keterlambatan waktu konversi dianggap sebagai indikasi kegagalan terapi. Literature review ini bertujuan untuk mengetahui pengaruh DM terhadap konversi apusan sputum setelah terapi fase intensif pada pasien tuberkulosis paru. Metode yang digunakan berupa review terhadap studi terkait pengaruh DM terhadap konversi apusan sputum TB paru selama 10 tahun terakhir (2010 – 2020). Hasil dari literature review ini menunjukkan bahwa DM berpengaruh terhadap keterlambatan konversi apusan sputum setelah terapi fase intensif. Pengaruh ini lebih signifikan pada pasien DM dengan kontrol glikemik yang buruk. Kata-kata kunci: diabetes mellitus, tuberkulosis, konversi apusan
Korelasi Ankle-Brachial Index (ABI) dan Kadar Hemoglobin Terglikasi (HbA1C) dengan Derajat Keparahan Kaki Diabetes Faris Naufal; Nanang Miftah Fajari; Dewi Indah Noviana Pratiwi
Homeostasis Vol 3, No 2 (2020)
Publisher : Homeostasis

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Abstract

Abstract: The severity of the diabetic foot can be determined by the Wagner-Meggit system which in this study uses 5 categories namely grade 1 – grade 5. ABI (Ankle-Brachial Index) is an evaluation of peripheral arterial disease in diabetic foot patients. HbA1c is a measure of changes in glucose concentration, as a measure of diabetes control. The purpose of this study was to determine the correlation between ABI values and HbA1c levels on the severity of diabetic foot based on the Wagner-Meggit classification. The method used was observational analytic with cross sectional approach. A total of 37 samples were obtained by consecutive sampling. Data analysis was performed using the Spearman test and logistic regression A significant correlation was obtained between ABI and the severity of diabetic foot (p=0.02;r=-0.320), no correlation was found between HbA1c and the severity of diabetic foot (p=0.258;r=-0.110). The results of logistic regression analysis showed no correlation between ABI (p=0.234; OR=0.025) and HbA1c (p=0.511; OR=1,150) with the severity of diabetic foot. Obtained Negelkerke R Square value of 0.095. Keywords: Diabetic foot, ABI, HbA1c, Wagner-Meggit classification. Abstrak: Derajat keparahan kaki diabetes dapat ditentukan dengan sistem Wagner-Meggit yang dalam penelitian ini menggunakan 5 kategori yaitu derajat 1 – derajat 5. ABI (Ankle-Brachial Index) merupakan pemeriksaan evaluasi penyakit arteri perifer pada pasien kaki diabetes. HbA1c merupakan pengukur perubahan konsentrasi glukosa, sebagai pengukur kontrol diabetes. Tujuan penelitian ini adalah mengetahui korelasi antara ABI dan HbA1c terhadap derajat keparahan kaki diabetes berdasarkan klasifikasi Wagner-Meggit. Metode yang digunakan adalah observasional analitik dengan pendekatan cross sectional. Sejumlah 37 sampel didapat secara consecutive sampling. Analisis data dilakukan menggunakan uji Spearman dan regresi logistik. Didapatkan korelasi bermakna antara ABI dengan derajat keparahan kaki diabetes (p=0,027; r=-0,320), tidak didapatkan korelasi antara HbA1c dengan derajat keparahan kaki diabetes (p=0,258 ; r=-0,110). Hasil analisa regresi logistik tidak didapatkan korelasi antara ABI (p=0,234; OR=0,025) dan HbA1c (p=0,511; OR=1,150) dengan derajat keparahan kaki diabetes. Didapatkan nilai Nagelkerke R Square sebesar 0,095. Kata kunci: kaki diabetes, ABI, HbA1c, klasifikasi Wagner-Meggit.
Literature Review: Korelasi HBA1C dan Mean Platelet Volume (MPV) terhadap Kaki Diabetes Mahdalena Mahdalena; Fauzia Noor Liani; Dewi Indah Noviana Pratiwi; Nanang Miftah Fajari; Azma Rosida
Homeostasis Vol 4, No 1 (2021)
Publisher : Homeostasis

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Abstract

Abstract: Diabetic foot ulcers are a major complication of diabetes mellitus. The mortality rate for diabetic foot ulcers ranges from 17- 32% and the amputation rate ranges from 15-30%. Diabetic foot ulcers associated with HbA1c levels> 6.5 patients are considered to have poor glucose control which can lead to various complications. Hyperglycemia in diabetes can increase platelet reactivity so it is necessary to check the Mean Platelet Volume (MPV) which is a biomarker of platelet reactivity. This literature review aims to collect data and analyze the correlation of HbA1c and Mean Platelet Volume (MPV) on the incidence of diabetic foot and to understand the mechanisms underlying changes in HbA1c levels and Mean Platelet Volume (MPV) that cause complications of diabetic foot. Literature sources are 15 journals obtained through medical journal databases, namely Pubmed, Science Direct and Google Scholar with the criteria of using English and Indonesian in the period 2009-2020. The results obtained in this study were the mean level of mean platelet volume (MPV) based on 10 literatures was 13.089 fl. Mean HbA1c levels from 15 literature HbA1c> 8%.  Keywords: correlation, kaki diabetes, diabetic foot ulcer, HbA1c, mean platelet volume. Abstrak:  Ulkus kaki diabetes merupakan komplikasi utama diabetes melitus. Angka kematian ulkus kaki diabetes berkisar antara 17- 32% dan laju amputasi berkisar 15- 30%. Ulkus kaki diabetes dikaitkan dengan kadar HbA1c >6,5 pasien dianggap memiliki kontrol glukosa yang buruk yang dapat menyebabkan berbagai komplikasi. Hiperglikemia pada diabetes dapat meningkatkan reaktivitas trombosit sehingga perlu pemeriksaan Mean platelet Volume (MPV) yang merupakan biomarker reaktivitas trombosit. Literature review ini bertujuan untuk mengumpulkan data dan menganalisis korelasi HbA1c dan Mean Platelet Volume (MPV) terhadap kejadian kaki diabetes dan memahami mekanisme yang mendasari perubahan kadar HbA1c dan Mean Platelet Volume (MPV) yang menyebabkan terjadinya komplikasi kaki diabetes. Sumber literatur berupa 15 jurnal yang diperoleh melalui database jurnal kedokteran, yaitu Pubmed, Science Direct dan Google Scholar dengan  kriteria menggunakan Bahasa inggris dan Bahasa Indonesia dalam kurun waktu 2009-2020. Hasil yang didapatkan dalam studi ini adalah Rerata kadar Mean Platelet Volume (MPV) berdasarkan 10 literatur adalah sebesar 13,089 fl. Rerata kadar HbA1c dari 15 literatur HbA1c>8%. Kata-kata kunci:  hubungan, kaki diabetes, diabetic foot ulcer, HbA1c, mean platelet volume.
Relationship between C-Reactive Protein Levels, Lactate Dehydrogenase, and Neutrophil-to-Lymphocyte Ratio with Coronavirus Disease 2019 Severity Hendra Wana Nur&#039;amin; I Nyoman Suarjana; Mohammad Rudiansyah; Nanang Miftah Fajari; Djallalluddin Djallalluddin
Berkala Kedokteran Vol 19, No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i1.15718

Abstract

Abstract: Risk stratification of Coronavirus disease 2019 (COVID-19) patients is very important to determine patient care and prognosis. The reliable parameters include C-reactive protein (CRP), lactate dehydrogenase (LDH), and neutrophil-lymphocyte ratio (NLR). This study aimed to determine the relationship between CRP, LDH, and NLR levels with the severity of COVID-19 patients. An observational study with a cross-sectional approach was conducted at Ulin Hospital Banjarmasin on 91 eligible subjects. A logistic regression test was conducted to determine the relationship between variables and the severity of COVID-19. The results showed that there was no significant relationship between CRP levels and the severity of COVID-19 (prevalence odds ratio (POR) 0.85, 95% confidence interval (CI 95%) 0.34-2.09, p=0.72). There was a significant difference between the mean LDH levels in severe COVID-19 compared to non-severe COVID-19 (1006 + 601.77 vs 543.5 + 480.41, p<0.001), with POR 4.23, 95% CI 95% 1.56-11.45, p=0.005; there was also a significant difference between the mean NLR values in severe COVID-19 compared to non-severe COVID-19 (9.01 + 6.32 vs 5.38 + 5.03, p=0.002) with POR of 12.21 CI 95% 3.80-39.31, p<0.001. This study showed that LDH levels and NLR values were important predictors of COVID-19 severity.
HUBUNGAN ANTARA USIA DAN JENIS KELAMIN DENGAN KEJADIAN STROKE PADA PASIEN DIABETES MELITUS DI RSUD ULIN BANJARMASIN Theresa Tyra Sertani; Nanang Miftah Fajari; Mohammad Bakhriansyah; Wiwit Agung Sri Nur Cahyawati; Dona Marisa
Homeostasis Vol 6, No 1 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i1.8802

Abstract

Diabetes melitus (DM) merupakan penyakit kronis yang ditandai dengan terjadinya peningkatan kadar glukosa darah melebihi normal atau hiperglikemia, salah satu penyakit kardiovaskuler yang berisiko besar terjadi pada penderita DM adalah stroke. Usia dan jenis kelamin merupakan faktor yang diduga berpengaruh terhadap terjadinya risiko stroke pada pasien DM. Tujuan penelitian ini untuk mengetahui hubungan antara usia dan jenis kelamin dengan kejadian stroke pada pasien DM. Penelitian observasional analitik ini menggunakan pendekatan potong lintang pada 108 pasien yang tercatat di pangkalan data milik Poliklinik Endokrin RSUD Ulin Banjarmasin yaitu BEST DIAB 2 (Borneo Wetland Study on Diabetes 2). Pengambilan sampel secara total sampling untuk pasien stroke dan simple random sampling untuk pasien tidak stroke dengan perbandingan 1:1. Data dianalisis dengan uji Fisher’s exact dan Chi-square menggunakan perangkat lunak statistik SPSS versi 26. Penelitian ini menunjukkan tidak ada hubungan antara usia (p=0,205) dan jenis kelamin (p=1,00) terhadap kejadian stroke pada pasien DM di RSUD Ulin Banjarmasin.
Co-Authors Abimanyu Abimanyu Afrianto, Muhammad Irawan Agung Pranoto Alfi Yasmina Annisa Halida Husna, Annisa Halida Azma Rosida Azma Rosida, Azma Dewi Indah Noviana Pratiwi Dewi Indah Noviana Pratiwi Djallalluddin Djallalluddin Djallalludin, Djallalludin Dona Marisa, Dona Faris Naufal Fauzia Noor Liani Firzatullah Ega Radyastra Franciscus Xaverius Hendriyono Hariyanto, Felix Hartono, Ivan Hasrianti, Nuvita Hendra Wana Nur&#039;amin I Nyoman Suarjana Ira Nurrasyidah Jeremy Eckhart S Parhusip Kholifah, Rika Mahdalena Mahdalena Marcellinus Anthony Raharjo Marwah Hulfah Merdayana Merdayana Mohammad Bakhriansyah Mohammad Bakhriansyah Mohammad Rudiansyah Muhammad Ghaly Maulana Muhammad Ilham Fadillah Munirah, Nida Nanik Tri Wulandari Nur'amin, Hendra Nur'amin, Hendra Wana Nur’amin, Hendra Wana Perdanakusuma, David Sontani Prenggono, Muhamad Darwin Saputri, Imelda Nita Siti Wasilah Syahputra, Harry Andhika Syarifa, Yulia Theresa Tyra Sertani Widi Aurelia Mirmaningtyas Wiwit Agung Sri Nur Cahyawati