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HUBUNGAN BODY MASS INDEX DENGAN DENSITAS PARENKIM PAYUDARA DARI PEMERIKSAAN MAMOGRAFI Amalia, Nurlinah; Aurora, Habiba; Siswidiyati
Majalah Kesehatan Vol. 10 No. 4 (2023): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/majalahkesehatan.2023.010.04.3

Abstract

Body Mass Index (BMI) merupakan prediktor komposisi tubuh yang membandingkan tinggi badan dan berat badan. Peningkatan BMI sering digunakan sebagai penanda bahwa banyak deposit lemak pada tubuh, salah satunya di payudara. BMI dihubungkan dengan kemungkinan terjadinya perubahan densitas parenkim payudara yang merupakan prediktor terkuat kejadian tumor payudara. Oleh karena itu, penelitian ini bertujuan untuk mengetahui hubungan BMI dengan densitas parenkim payudara dari pemeriksaan mamografi. Penelitian ini bersifat analitik observasional dengan menggunakan metode cross sectional yang dilakukan pada 27 subjek penelitian yang berasal dari Perhimpunan Radiografer Indonesia (PARI) dan kelompok Dharma Wanita Universitas Brawijaya di RSUD dr. Saiful Anwar. Berdasarkan hasil penelitian didapatkan bahwa BMI memiliki hubungan yang signifikan dengan densitas parenkim payudara (Kruskal wallis, p=0,010) dan BMI berkorelasi negatif dengan densitas parenkim payudara (Spearman, p=0,000) dengan nilai correlation coefficient bersifat kuat (-0,626). Kesimpulan dari penelitian ini adalah BMI berkorelasi negatif dengan densitas parenkim payudara.
Potential Efficacy of Artificial Intelligence in Mammography for Breast Cancer Screening: Current Evidence from Meta-Analysis Amalia, Nurlinah; Nurdiana, Farah; Pradyaputri, Naura Shafa
Indonesian Journal of Cancer Vol 19, No 4 (2025): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i4.1353

Abstract

Background: Artificial intelligence (AI), an advancing field of data science, has been applied in mammography screening for early detection of breast cancer in an effort to enhance screening participants' outcomes. Screening is crucial to halting the spread of breast cancer. These days, mammography is typically used in screenings conducted by radiologists. Therefore, alternative diagnostic methods are needed to provide a diagnostic solution that is efficient in terms of both time and resources. This review aims to evaluate the accuracy of AI applications in radiology, specifically in mammographic image interpretation, to determine whether AI can serve as an evidence-based recommendation for breast cancer screening. Methods: We conducted a systematic review and meta-analysis following the PRISMA guidelines. Literature searches were performed across multiple databases, including PubMed, ScienceDirect, and SpringerLink. The inclusion criteria were based on the PICOs framework, focusing on individuals at risk of breast cancer undergoing mammographic screening, where AI was used to interpret the images and compared to a radiologist. Exclusion criteria included studies involving patients with diagnosed breast cancer, non-human studies, non-English, books, paid articles, and review articles. The primary outcomes of interest were the sensitivity and specificity of AI in detecting breast cancer from mammograms. Meta-analysis was conducted using STATA software, while the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool was employed to evaluate study qualityResults: A total of 2,412,102 mammograms from twenty-six studies were included in this analysis. The results indicated that AI demonstrated moderate sensitivity [84% (99.92% CI: 99.91 – 99.92)] and specificity [87% (99.97% CI: 99.97 – 99.97)] with a p-value (0.001). Conclusions: These results suggest that AI has potential as a breast cancer diagnosis tool in the future. Radiologists can become more accurate with AI algorithms, which are useful for screening, cutting down on unnecessary recall rates, and reducing effort.
PROBIOTIC SUPPLEMENTATION IN INFANTILE COLIC: A COMPARATIVE LITERATURE REVIEW BETWEEN BREASTFED AND FORMULA-FED INFANTS Sais, Vira Cendana; Putri, Erika Aini; Yustisiani, Aliffa Neta; Falakhi, Qoniatunnisa Nuzulul; Penadi, Hafidhania; Amalia, Nurlinah
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 15, No 3 (2026): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v15i3.53313

Abstract

Background: Infantile colic is a functional gastrointestinal disorder in infants under five months, marked by excessive, unexplained crying, and is increasingly linked to gut dysbiosis and intestinal inflammation. Probiotics may help relieve colic by modulating gut microbiota, with effects differing by feeding type. Objective: This study aims to evaluate the effectiveness of probiotics in managing infantile colic, with a focus on differences in outcomes between exclusively breastfed and formula-fed infants. Methods: This literature review identifies randomized controlled trials and cohort studies involving infants aged 0–12 months that are diagnosed with colic and receiving probiotics. The outcomes are crying frequency and duration, or symptom improvement, and compared effects between exclusively breastfed and formula-fed infants. Seven databases were searched using combinations of relevant keywords, limited to publications from the past five years. Data were synthesized using narrative qualitative analysis. Results: From 1,886 initially identified records, 29 studies met the eligibility criteria after screening and full-text assessment. Among the included studies, 13 investigated probiotics alone, 10 focused on breastfed infants, 4 on formula-fed infants, and 2 involved both feeding types. Most studies supported the efficacy of Lactobacillus reuteri DSM 17938 in reducing crying duration and frequency, particularly in breastfed infants. Formula-fed infants showed variable outcomes, potentially influenced by probiotic strain, feeding composition, and study design. Conclusion: Probiotics, especially Lactobacillus reuteri, demonstrate promising effects in alleviating colic symptoms, predominantly among breastfed infants. Feeding type may act as a modifier of probiotic efficacy, highlighting the need for tailored interventions based on nutritional context.