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All Journal Jurnal Analis Medika Biosains (JAMBS) Jaringan Laboratorium Medis JURNAL KESEHATAN BHAKTI HUSADA Jurnal Kesehatan Tambusai Jurnal Kesehatan
Rahmawati, Previta Zeizar
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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HUBUNGAN PEMERIKSAAN ANTIGEN NONSTRUKTURAL 1 (NS1) DAN JUMLAH NILAI HEMATOKRIT PADA PASIEN POSITIF DEMAM BERDARAH DENGUE DI PUSKESMAS TUMPANG Wijaya, Anastasya; Husnah, Yeni Avidhatul; Rahmawati, Previta Zeizar
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.36736

Abstract

Kasus DBD banyak terjadi di Indonesia karena wilayah tropis dan memiliki curah hujan cukup tinggi, menyebabkan penyebaran Aedes aegypti yaitu nyamuk penyebab DBD berkembang pesat. Tujuan penelitian ini untuk mengetahui hubungan jumlah nilai hematokrit dengan pemeriksaan Antigen NS1 pada pasien demam berdarah dengue. Metode penelitian ini menggunakan desain observasional analitik cross-sectional. Sampel penelitian berjumlah 116 data rekam medis di Puskesmas Tumpang Kabupaten Malang dari Januari – 15 Mei 2024. Hasil analisis data menggunakan Uji Korelasi Pearson menunjukkan tidak terdapat hubungan yang signifikan antara pemeriksaan Antigen NS1 dengan jumlah nilai hematokrit pada pasien DBD (p > 0,05).  Pasien dengan hasil pemeriksaan NS1 positif dan negatif memiliki nilai hematokrit yang tidak jauh berbeda, tetapi didapati perbedaan jumlah nilai hematokrit balita dan dewasa berdasarkan nilai persentase, balita tergolong lebih rendah dari orang dewasa tetapi masih diangka normal. Remaja lebih banyak terserang DBD persentasenya mencapai 45%, DBD paling banyak terjadi pada perempuan persentasenya yaitu 53%, pemeriksaan Dengue positif NS1 sebesar 97% dan 3% negatif NS1 tetapi positif IgM/IgG. Saran penelitian selanjutnya perlu dilakukan penelitian lebih lanjut dengan menambah variabel seperti hubungan pemeriksaan NS1 Ag dengan hematokrit dan trombosit berdasarkan omset demam dengan melihat terjadi/tidaknya hemokonsentrasi dan trombositopenia sebagai antisipasi terjadinya fase kritis demam berdarah dengue.
Pemeriksaan Dampak Mengkonsumsi Minuman Beralkohol Terhadap Kadar Enzim Aspartat Aminotransferase (AST) dan Alanine Aminotransferase (ALT) Fatmawati, Shinta; Husnah, Yeni Vidhatul; Rahmawati, Previta Zeizar
Jaringan Laboratorium Medis Vol 6, No 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.11777

Abstract

Aspartat aminotransferase (ast) and alanine aminotransferase (Alt) or which is the enzyme transaminase used liver function tests. When alcohol enters the body, a metabolism in the liver is carried out with an end result of acetydehid when an excessive dose causes liver damage. The purpose of research to determine whether or not there is a correlation between the consumption of alcohol and its blast of bank. this study is a non-experiment of quantitative experimentation with a sampling technique. The respondents in this study are 24 alcohol drinkers of NTT students in the unfortunate city. And sample analysis methods of the kinetic ifcc and the chemical analyzer clinic - the mindray analyzer. On 24 of the respondents of all sexs-men will be analyzed based on long consumption, high consumption of alcohol, and heavy drink-alcohol consumption. The research data obtained will be done in a statistical test using the Pearson correlation test. Studies conducted on alcohol drinkers for a normal ast result are 18 respondents and abnormal results of 6. Studies on alcohol drinkers for normal test levels included 19 individuals and abnormal results for 5. The Pearson correlation test between the amount of consumption between the ast consumption is 0,184 and p-value 0.05, and the high consumption of alcohol is 0.508 and the value of p-value 0.05, and the amount of drinking is an e-0.405 and p-value 0.05. Studies between consumption length and Alt levels have found a very weak link of 0,033 and p-value 0.05, the high consumption of alcohol is 0,426 and the value of p-value 0.05, and the high drinking relationship of weak value are = 0.315 and p-value 0.05. The study has had a negative impact on excessive consumption of alcohol, raising levels of ast and Alt especially on high-alcohol drinkers and excessive drinking frequency.
GAMBARAN KADAR KREATININ PADA PEMINUM ALKOHOL DI KUMUNITAS TIMUR KOTA MALANG Dhila, Yuliana; Rahmawati, Previta Zeizar; Husna, Yeni Avidatul
Jurnal Kesehatan Bhakti Husada Vol 10 No 2 (2024): JURNAL KESEHATAN BHAKTI HUSADA
Publisher : LPPM STIKes BHAKTI HUSADA CIKARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37848/jurnal.v10i2.210

Abstract

Abstract : Latar belakang: Peminum di Indonesia semakin banyak, berdasarkan data dari Badan Pusat Statistik tahun 2022, menunjukkan bahwa konsumsi alkohol oleh penduduk umur 15 tahun dalam satu tahun terakhir di perkotaan dan perdesaan adalah sebesar 0,33%. Hal ini akan bisa merusak fungsi ginjal dengan meningkatnya kadar kreatinin dalam darah. Penelitian ini bertujuan untuk mengetahui gambaran kadar kreatinin pada peminum alkohol di komunitas Timur Kota Malang. Metode: Penelitian ini menggunakan deskriptif kuantitatif analitik dengan menggambarkan suatu keadaan atau masalah yang digali melalui pengamatan yang terjadi dilapangan. Jenis penelitian deskriptif yang digunakan dalam penelitian ini. Hasil: Berdasarkan hasil pengukuran kadar kreatinin dengan kadar Rendah 0,7 mg/dl, kadar normal 0,7-1,3 mg/dl, dan kadar tinggi 1,3 mg dl pada 20 orang responden.Merujuk pada hasil penelitian tentang kadar kreatinin pada pria peminum alkohol di komunitas Timur Kota Malang dengan berdasarkan hasil penelitian dapat disimpulkan hasil pemeriksaan pada 20 responden yang memiliki kadar kreatinin normal sebanyak 18 responden (90%), memiliki kadar kreatinin rendah sebanyak 2 responden (10%). Hal ini menunjukkan bahwa lebih banyak masyarakat yang mengonsumsi minuman beralkohol memiliki kadar kreatinin yang normal. Abstract: Alcohol consumption in Indonesia continues to rise, especially in urban areas. Alcohol drinkers are at risk of kidney function impairment due to elevated creatinine levels. Purpose: This study aims to describe creatinine levels among alcohol drinkers in the East Community of Malang City. Results: A total of 18 respondents (90%) had normal creatinine levels (0.7-1.3 mg/dl), while 2 respondents (10%) had low creatinine levels (<0.7 mg/dl). Correlation tests showed no significant relationship between the duration of alcohol consumption and creatinine levels. Conclusion: The majority of alcohol drinkers in this community have creatinine levels within the normal range, although a few showed low levels. There was no significant correlation between the duration of alcohol consumption and creatinine levels. Keywords: Creatinine, Alcohol, East Community
Gambaran Kadar Karboksihemoglobin (Cohb) Pada Pekerja Bengkel Berdasarkan Usia Dan Lama Bekerja Nila, Ayu; Rahmawati, Previta Zeizar; Husna, Yeni Avidhatul
Jurnal Kesehatan Bhakti Husada Vol 10 No 2 (2024): JURNAL KESEHATAN BHAKTI HUSADA
Publisher : LPPM STIKes BHAKTI HUSADA CIKARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37848/jurnal.v10i2.215

Abstract

perkembangan zaman membuat kualitas udara semakin buruk zat yang menjadi salah satu pencemaran udara ialah karbon monoksida yang di hasilkan oleh kendaraan bermotor. Tujuan: Penelitian ini bertujuan untuk mengidentifikasi pola dan hubungan antra variabel penelitian untuk mengetahui gambaran kadar karboksihemoglobin (COHb) pada pekerja bengkel di kota malang berdasarkan usia dan lama bekerja. Metode: Penelitian ini menggunakan desain deskriptif yang bertujuan umtuk mengambarkan atau menguraikan karakteristik pekerja bengkel, kadar (COHb) di ukur menggunakan metode Spektrofotometer UV-Vis dengan panajang gelombang 546nm. Hasil: Sebanyak 1 responden memiliki kadar COHb <3,5% sementara 10 responden memiliki kadar COHb >3,5% telah di lalukan uji korelasi berdasarkan usia mendapatkan korelasi siknifikan pada level 0,01 menunjukkan bahwa adanya hubungan yang sangat kuat uji korelasi berdasarkan lama bekerja menunjukkan hasil siknifikan secara statistic. Kesimpulan: Gambaran kadar COHb pada pekerja bengkel dengan jumlah 11 responden berdasarkan usia dan lama bekerja yang di mana terdapat 1 responden memiliki kadar COHb normal dan 10 responden memiliki kadar COHb yang melebihi batas normal.
The Effect of Jasmine Flower Extract (Jasminum sambac) on the Lethal Dose Effect of LT on Aedes aegypti Mosquito Larvae Saroh, Putri Rohmah Muya; Mahtuti, Erni Yohani; Rahmawati, Previta Zeizar
Jurnal Kesehatan Vol 18, No 1 (2025): Jurnal Kesehatan
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jk.v18i1.6897

Abstract

Pendahuluan: Demam Berdarah Dengue Demam berdarah (DBD) telah berkembang menjadi masalah kesehatan utama bagi masyarakat Indonesia. Pengendalian vektor untuk memutus mata rantai penularan demam berdarah merupakan salah satu cara pencegahan penyakit demam berdarah. Salah satu cara yang efektif untuk mengendalikan demam berdarah adalah dengan mengendalikan jentik menggunakan insektisida. Penggunaan insektisida secara terus-menerus dapat menimbulkan efek samping yang berbahaya bagi lingkungan. Oleh karena itu, diperlukan insektisida alami dengan memanfaatkan bahan-bahan di sekitar kita yang mengandung zat sebagai insektisida, salah satunya adalah bunga melati (Jasminum sambac). Metode: Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak bunga melati terhadap larva Aedes aegypti dengan konsentrasi 10%, 15%, 20%, 25% dengan waktu kontak 5 menit, 10 menit, 15 menit, 20 menit, 25 menit, 30 menit, 35 menit, 40 menit, 45 menit, 50 menit, 55 menit, 60 menit. Jenis penelitian ini adalah eksperimen dengan rancangan acak lengkap. Cara pembuatan ekstraksi dengan cara ceration menggunakan etanol 96%. Sampel yang digunakan adalah larva Aedes aegypti instar III. Hasil: Hasil penelitian ini menunjukkan bahwa konsentrasi yang menimbulkan efek knockdown 50% berdasarkan estimasi adalah pada konsentrasi 14,019%. Hasil analisis statistik dengan anova p=0,05 menunjukkan adanya pengaruh yang signifikan dari interaksi konsentrasi dan waktu kontak (p=0,19) terhadap kematian larva Aedes aegypti. Kesimpulan: Penelitian ini telah membuktikan bahwa ekstrak bunga melati (jasminum sambac) efektif sebagai larvasida. Dari hasil analisis probit didapatkan bahwa konsentrasi yang menimbulkan efek knockdown 50% berdasarkan estimasi adalah pada konsentrasi 14,019%.     Introduction: Dengue Fever Dengue fever (DHF) has developed into a major health problem for Indonesian society. Vector control to stop the chain of transmission of dengue fever is one way to prevent dengue fever. One effective way to control dengue fever is to control larvae using insecticides. Continuous use of insecticides can cause side effects that are harmful to the environment. Therefore, natural insecticides are needed by utilizing materials around us that contain substances as insecticides, one of which is jasmine flowers (Jasminum sambac). Method: This study aims to determine the effect of jasmine flower extract on Aedes aegypti larvae with concentrations of 10%, 15%, 20%, 25% with contact times of 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes, 35 minutes, 40 minutes,45 minutes,50 minutes,55 minutes,60 minutes. This type of research is an experiment with a completely randomized plan. How to make extraction by ceration using 96% ethanol. The samples are third instar Aedes aegypti larvae. Results: The results of this research showed that the concentration that caused a 50% knockdown effect based on estimates was at a concentration of 14,019%. The results of statistical analysis with anova p=0.05 showed a significant effect of the interaction of concentration and contact time (p=0.19) on the death of Aedes aegypti larvae. Conclusion: This research has proven that jasmine flower extract (jasminum sambac) is effective as a larvicide. From the results of the probit analysis, it was found that the concentration that caused a 50% knockdown effect based on estimates was a concentration of 14,019%.
Description Of C-Reactive Protein (CRP) In Patients With Type 2 Diabetes Mellitus At Mulyorejo Health Center In Malang City Kapero, Febriyanti Wora; Mahtuti, Erni Yohani; Rahmawati, Previta Zeizar
Jurnal Analis Medika Biosains (JAMBS) Vol 10, No 2 (2023): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v10i2.320

Abstract

Diabetes Mellitus Type 2 is a metabolic disorder condition characterized by hyperglycemia, due to decreased insulin secretion. Many cytokines play a role in the acute phase response, so that markers such as CRP increase in patients with type 2 DM. The type of research used in this study is descriptive research, which describes the results of CRP examination in patients with type 2 diabetes. Examination of respondents' serum C-Reactive Protein (CRP) levels was carried out qualitatively using the Latex Agglutination method and followed by a semi-quantitative method, namely dilution to determine the level of inflammation. The results of CRP examination on 30 serum samples that have been carried out on patients with Type 2 Diabetes Mellitus found that 29 (96.7%) were positive and 1 (3.3%) of respondents were negative. The group of CRP levels for titer 12 was 5 samples (16.7%), titer 24 was 17 samples (56.7%), titer 48 was 5 samples (16.7%), and titer 96 was 2 samples (6.7). %). The results of the four groups with the highest CRP levels, namely a titer of 24 mg/L as many as 17 samples (56.7%) showed that some of the CRP levels were higher than normal. Conclusion Almost all respondents with type 2 Diabetes Mellitus had positive C-Reactive Protein examination results and a small proportion of type 2 Diabetes Mellitus patients had negative C-Reactive Protein examination results. 
Pemeriksaan Dampak Mengkonsumsi Minuman Beralkohol Terhadap Kadar Enzim Aspartat Aminotransferase (AST) dan Alanine Aminotransferase (ALT) Fatmawati, Shinta; Husnah, Yeni Vidhatul; Rahmawati, Previta Zeizar
Jaringan Laboratorium Medis Vol. 6 No. 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.11777

Abstract

Aspartat aminotransferase (ast) and alanine aminotransferase (Alt) or which is the enzyme transaminase used liver function tests. When alcohol enters the body, a metabolism in the liver is carried out with an end result of acetydehid when an excessive dose causes liver damage. The purpose of research to determine whether or not there is a correlation between the consumption of alcohol and its blast of bank. this study is a non-experiment of quantitative experimentation with a sampling technique. The respondents in this study are 24 alcohol drinkers of NTT students in the unfortunate city. And sample analysis methods of the kinetic ifcc and the chemical analyzer clinic - the mindray analyzer. On 24 of the respondents of all sexs-men will be analyzed based on long consumption, high consumption of alcohol, and heavy drink-alcohol consumption. The research data obtained will be done in a statistical test using the Pearson correlation test. Studies conducted on alcohol drinkers for a normal ast result are 18 respondents and abnormal results of 6. Studies on alcohol drinkers for normal test levels included 19 individuals and abnormal results for 5. The Pearson correlation test between the amount of consumption between the ast consumption is 0,184 and p-value > 0.05, and the high consumption of alcohol is 0.508 and the value of p-value 0.05, and the amount of drinking is an e-0.405 and p-value 0.05. Studies between consumption length and Alt levels have found a very weak link of 0,033 and p-value > 0.05, the high consumption of alcohol is 0,426 and the value of p-value 0.05, and the high drinking relationship of weak value are = 0.315 and p-value > 0.05. The study has had a negative impact on excessive consumption of alcohol, raising levels of ast and Alt especially on high-alcohol drinkers and excessive drinking frequency.
Co-Authors Dhila, Yuliana Erni Yohani Mahtuti Fatmawati, Shinta Husna, Yeni Avidatul Husna, Yeni Avidhatul Husnah, Yeni Avidhatul Husnah, Yeni Vidhatul Kapero, Febriyanti Wora Nila, Ayu Saroh, Putri Rohmah Muya Wijaya, Anastasya