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All Journal JURNAL FARMASIMED (JFM) Jurnal Pengmas Kestra (JPK)
Zebua, Kristian Cahayani
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Health Professions Medicine & Pharmacology Nursing Public Health

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SEMINAR OF EVALUATION OF THE USE OF CIPROFLOXACIN ANTIBIOTICS IN INFECTION PATIENTS URINARY TRACT (PUT) IN CARE INSTALLATION HOSPITAL GRANDMED LUBUK PAKAM: SEMINAR OF EVALUATION OF THE USE OF CIPROFLOXACIN ANTIBIOTICS IN INFECTION PATIENTS URINARY TRACT (PUT) IN CARE INSTALLATION HOSPITAL GRANDMED LUBUK PAKAM Sihombing, Yanna Rotua; Siska, Fitri; Zebua, Kristian Cahayani; Nasution, Dina Wahyuni
JURNAL PENGMAS KESTRA (JPK) Vol. 2 No. 2 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (472.278 KB) | DOI: 10.35451/jpk.v2i2.1439

Abstract

Urinary Tract Infection (UTI) This is an infectious disease characterized by the growth and multiplication of bacteria in the urinary tract. The most common etiology in more than 80% of uncomplicated UTI cases is Escherichia coli, and less than 50%, Proteus spp, Klebsiella pneumoniae, Enterobacter spp, Pseudomonas aeruginosa, Staphylococcus, and Enterococcus. Candida species are a common cause of urinary tract infection in patients with severe chronic catheterization. The clinical forms of UTI are classified according to age, intensity of inflammatory response, and location of urinary tract infection. Children aged 2 months to 2 years with a UTI require special attention because they are likely to have atypical clinical presentations, invasive urine specimen collection, and kidney injury. This study aims to determine the dosage and composition of the antibiotic ciprofloxacin in patients with urinary tract infections at Grandmed Lubuk Pakam Hospital for the period November-December 2021. The method used is a descriptive assessment because it aims to provide an objective picture or description of the situation. Data collection was carried out retrospectively. Both research by reviewing historical information, as well as data collection by observing the medical records of urinary tract infection patients at Grandmed Lubuk Pakam Hospital in 2021
The EVALUATION OF THE USE OF ANTI-INFLAMMATORY DRUGSIN PATIENTS RHEUMATOID ARTHRITIS OUTPATIENT AT GRANDMED HOSPITAL LUBUK PAKAM Sihombing, Yanna Rotua; Marbun, Romauli Anna Teresia; Zebua, Kristian Cahayani; Lestari, Dayana
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1315

Abstract

Rheumatoid arthritis is an autoimmune disease characterized by inflammation of the joints that can become chronic. Rational use of drugs aims to ensure that patients get safe and effective treatment in the right time frame and at an affordable price according to their needs In the outpatient facility of Lubuk Pakam Hospital, patients experience symptoms such as pain, inflammation, morning joint stiffness and difficulty moving at appropriate doses. This study aims to aim to obtain an objective picture or picture of the situation. Data collection was carried out retrospectively, namely by observing the medical records of rheumatoid arthritis patients at Grandmed Lubuk Pakam Hospital in 2021. A total of 13 (56.5%) female patients and 10 (56.5%) (43.5%) male patients, according to the number of rheumatoid arthritis patients at the outpatient facility of GrandMed Lubuk Pakam Hospital in 2021. This makes the inclusion criteria for all anti-inflammatory agents incomplete in rheumatoid arthritis and the exclusion criteria for all medical records in rheumatoid arthritis patients. Analysis of data based on age, gender, rationality of the drug, correct indications, correct patient, correct drug, correct dosage. The Outpatient Study of GrandMed Lubuk Pakam Hospital 2021 is: Correct Indications (100%), Correct Patients (100%), Correct Drugs (100%), Correct Dosage (91.3%). The treatment of patients with rheumatoid arthritis at GrandMed Lubuk Pakam Hospital can still be said to be fully good
Formulation of Ethanol Extract Cream of Sikkam Leaves (Bischofia javanica Blume) as an Antifungal Against Candida albicans wulandari, Suci; Br Purba, Sri Ulina; Miranti; Zebua, Kristian Cahayani
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2293

Abstract

Skin health issues in Indonesia, including those caused by fungal infections such as (Candida albicans), can lead to various conditions like candidiasis, scabies, tungiasis, and leprosy. This study aims to evaluate the potential of sikkam leaf extract in developing an antifungal cream to combat (Candida albicans). Fungi are eukaryotic organisms that cannot photosynthesize and reproduce through branching filaments composed of hyphae. Fungi can thrive in diverse environments such as water, soil, and decaying organic matter. A cream is a semi-solid emulsion preparation in which one or more medicinal substances are dissolved or dispersed within a base. This formulation determines the cream’s effectiveness, including the optimal ethanol extract concentration needed for antifungal activity. Extraction of sikkam leaves was conducted using maceration with 70% ethanol, and creams were formulated with extract concentrations of 5%, 10%, and 15%. Data were analyzed using the Kruskal-Wallis test. The study results showed that sikkam leaf-based creams meet quality standards, including organoleptic properties, homogeneity, pH, spreadability, and physical stability. Effectiveness testing indicated that creams with 5%, 10%, and 15% concentrations produced inhibition zones against (Candida albicans) with average diameters of 6.3 mm, 9 mm, and 15.3 mm, respectively. The higher the extract concentration, the stronger the inhibition of fungal growth. The cream with a 15% concentration proved to be the most effective, with inhibition classified as strong. Thus, sikkam leaf extract shows potential as a key ingredient for antifungal cream formulations.
Co-Authors Br Purba, Sri Ulina Lestari, Dayana Miranti Nasution, Dina Wahyuni Sihombing, Yanna Rotua Siska, Fitri Suci Wulandari