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All Journal International Journal of Health Science (IJHS) Buletin Penelitian Kesehatan
Mofu, Renold M.
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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EFFORTS TO PREVENTING MALARIA IN COMMUNITIES NOLOKLA VILLAGE, EAST SENTANI DISTRICT, JAYAPURA REGENCY Mofu, Renold M.; Wiwiek Mulyani; Andreas C. Ayomi
International Journal Of Health Science Vol. 3 No. 1 (2023): March : International Journal of Health
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v3i1.787

Abstract

Malaria is one of the public health problems that can lead to death. Papua is one of the highest contributors to malaria cases. Therefore, the community needs to make efforts to prevent malaria. This study aims to obtain information about malaria prevention efforts carried out by the community in Nolokla Village. This type of research is descriptive. The sampling technique uses Stratified Random Sampling. A sample of 98 households was selected by tier. Data were collected using questionnaires and observation sheets (cheklists). The results showed that those who did not meet the requirements in this study were mosquito shelters (100%), the habit of going out at night (86%), mosquito repellent (77%), the habit of opening the door at night (78%), and for those who met the requirements, namely the use of mosquito nets (89%), the use of gauze wire in house ventilation (65%), the use of ceilings 64%, home hygiene efforts (71%), the habit of opening windows at night (100%). The prevention carried out by the people of Kampung Noloklais the use of mosquito nets in their bedrooms, the use of mosquito screen wire in the ventilation of the house, the place where mosquitoes are still found around the house and the use of health services tends to be rarely used by the community. For this reason, health workers, especially sanitation and health promotion workers, are more active in holding counseling and inviting village elements to protect the environment.
Potential of Malaria Vaccine in Eliminating Malaria: a Systematic Literature Review Mofu, Renold M.; Mulyani, Wiwiek; Purba, Lilys Irianty Natalia
Buletin Penelitian Kesehatan Vol. 52 No. 1 (2024)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/bpk.v52i1.3950

Abstract

Introduction: Malaria vaccines show significant potential for disease control but face challenges, including declining efficacy over time and resistance to drugs and insecticides. Despite the initial success of vaccines like RTS,S/AS01, an integrated approach is still needed to address malaria’s complex transmission dynamics across endemic regions. This review examines the current status, challenges, and future prospects of malaria vaccine development, focusing on the impact of combining pre-erythrocytic vaccines and transmission-blocking drugs using mathematical modeling to enhance their effectiveness in reducing transmission. Methods: A systematic literature review was conducted using the PICO framework to evaluate the effectiveness of malaria vaccines in reducing disease transmission. The review included studies involving vulnerable populations, particularly children in African countries. It compared the effectiveness of malaria vaccines with other control strategies, such as insecticide-treated bed nets and antimalarial drugs. Five relevant primary journals were analyzed using databases like PubMed, Scopus, and Google Scholar. Results: Findings reveal that newly developed malaria vaccines have significant potential to reduce malaria cases. However, large-scale implementation and regular vaccination strategies are required for sustained effectiveness. Genetic studies highlight the emergence of resistance, emphasizing the need for adaptable vaccines and strategies. Conclusion: Malaria vaccines, while promising, face obstacles such as waning efficacy and resistance. A combined strategy involving vaccines and transmission-blocking treatments is essential for global malaria elimination. Further research and strategic implementation are needed to optimize vaccine effectiveness and overcome these challenges.
Co-Authors Andreas C. Ayomi Mulyani, Wiwiek Purba, Lilys Irianty Natalia Wiwiek Mulyani