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PENGHAMBATAN AKTIVITAS α-GLUKOSIDASE DARI EKSTRAK METANOL BUNGA BUGENVIL (Bougainvillea glabra Choisy) Puspitasari, Intan Dessy; Saleh, Chairul; Hairani, Rita; Ruga, Ritbey
JURNAL ATOMIK Vol 9 No 1 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i1.1276

Abstract

The test of Phytochemical screening and antidiabetic activity of methanol extract of bugenvil (Bougainvillea glabra Choisy) flower against α-glucosidase inhibition have been conducted. This study aims to determine the content of secondary metabolite compounds and the effectiveness of the methanol extract of bugenvil flower against α-glucosidase activity. Phytochemical test showed that the methanol extract contained secondary metabolite compounds namely alkaloids, flavonoids, steroids, phenolics and saponins. By 50 µg/mL, the methanol extract of bugenvil flower can inhibit α-glucosidase activity with a percent inhibition value of 79.42% while acarbose as a positive control in this study exhibited antidiabetic activity against α-glucosidase of 99.30% at a concentration of 0.00006 µg/mL.