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All Journal PROSIDING SEMINAR KIMIA Jurnal Kimia Mulawarman Science and Technology Indonesia JURNAL ATOMIK Jurnal Ilmiah Sains Jurnal Abdimas Mahakam
Rita Hairani
Jurusan Kimia FMIPA Universitas Mulawarman
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Energy Environmental Science Materials Science & Nanotechnology Mathematics Physics Other

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validasi Rika anggraini; Rita Hairani; Aman Sentosa Panggabean
JURNAL KIMIA MULAWARMAN Vol 16 No 1 (2018)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v16i1.667

Abstract

The research about validation of the method of Hg determination on the sample from wastewater treatment plant (WWTP) PT. Badak NGL Bontang, Kalimantan Timur using cold vapour-atomic absorption spectrophotometer (CV-AAS) techniques has been conducted. To obtain a valid measurement result, determinations of the important several parameters that influence the method validation are used. The results of research showed that 20% SnCl2 solution could be used as a reducing agent. The analytic performance of measurement obtain is good, showed with the linearity (r) value ≥ 0.995, LOD was 0.2530 ppb, LOQ was 0.8432 ppb, MDL was 0.6427 ppb and repeatability and reproducibility are shown as % RSD < 2/3 CV Horwitz values. The accuracy of this method is very good with a percentage of recovery value of 114.88%. Based on the results of this research, CV-AAS method can be used in the determination of Hg in WWTP samples with the valid results.
Isolasi dan Identifikasi Senyawa Metabolit Sekunder dari Rimpang Temu Hitam (Curcuma aeruginosa Roxb) Yuwinda Cindy Elisabet Panggabean; Eva Marliana; Rita Hairani; Swandari Paramita; Sjarif Ismail
JURNAL KIMIA MULAWARMAN Vol 18 No 1 (2020)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v18i1.807

Abstract

Isolation and identification of secondary metabolites from ethyl acetate fraction of rhizomes of Temu Hitam (Curcuma aeruginosa Roxb.) have been done. The separation of ethyl acetate fraction and further seperation were performed using gravity column chromatography with n-hexane and ethyl acetate (9.5:0.5-3:7) as solvent systems to obtain the isolate (oil;0.0216 g). Based on UV analysis of isolate, the result showed 1 peak at ? 206.14 nm. In addition, the FT-IR spectra indicated the presence of functional groups of OH, aliphatic C-H, C=O and C-O. According to the result of the UV and FT-IR spectra, the isolate can be identified as terpenoid.
UJI FITOKIMIA DAN UJI TOKSISITAS EKSTRAK ETANOL BATANG BAJAKAH (Uncaria cordata (Lour.) Merr.) TERHADAP Artemia salina L. Wardani, M. Rizky; Erwin, Erwin; Hairani, Rita
PROSIDING SEMINAR KIMIA Vol 2 No 2 (2024): Prosiding SNKT III 2023
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Uncaria is a genus of plants that grows in the Kalimantan forest. Many species in this genus are used as traditional medicines, so this genus is interesting to be studied for its chemical compound content. One species in this genus is Uncaria cordata which is also known as Bajakah plant. The aim of this study was to determine the content of secondary metabolite compounds and the level of toxicity of the ethanol extract of U. cordata stems on Artemia salina L. The methods used in this research were extraction, phytochemical tests and toxicity test using the Brine Shrimp Lethality Test (BSLT) method. The results of the phytochemical test showed that the ethanol extract of U. cordata stems contained alkaloids, triterpenoids, phenolics, flavonoids, quinones, and saponins. Furthermore, according to of the toxicity test showed that the ethanol extract of U. cordata stems had toxicity level of 75.03 ppm in the toxic category (LC50 < 1000 ppm). Based on these results, it can be concluded that the ethanol extract of U. cordata stems has the potential to have bioactivity because it is toxic to Artemia salina L. shrimp larvae. Keywords: Bajakah, Phytochemicals, Secondary Metabolites, Toxicity, Uncaria cordata
POTENSI AKTIVITAS ANTIOKSIDAN EKSTRAK METANOL BUNGA ASOKA (Ixora coccinea L.) Ramadhan, Aulia; Saleh, Chairul; Hairani, Rita; Ruga, Ritbey
JURNAL ATOMIK Vol 9 No 1 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i1.1273

Abstract

Extraction of asoka (Ixora coccinea L.) flowers, phytochemical screening, and antioxidant activity of methanol extract of asoka flowers have been conducted. This study aimed to determine the content of secondary metabolites in the methanol extract of asoka flowers and its antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The phytochemical screening test revealed that the methanol extract of asoka flowers contained secondary metabolites such as flavonoids, alkaloids, triterpenoids and saponins. With 1 mg/mL, the methanol extract exhibited potential as an antioxidant with an inhibition percentage of 88.10% while vitamin C as a standard used in this study at 1 mg/mL showed an antioxidant activity of 99.23%.
PENGHAMBATAN AKTIVITAS α-GLUKOSIDASE DARI EKSTRAK METANOL BUNGA BUGENVIL (Bougainvillea glabra Choisy) Puspitasari, Intan Dessy; Saleh, Chairul; Hairani, Rita; Ruga, Ritbey
JURNAL ATOMIK Vol 9 No 1 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i1.1276

Abstract

The test of Phytochemical screening and antidiabetic activity of methanol extract of bugenvil (Bougainvillea glabra Choisy) flower against α-glucosidase inhibition have been conducted. This study aims to determine the content of secondary metabolite compounds and the effectiveness of the methanol extract of bugenvil flower against α-glucosidase activity. Phytochemical test showed that the methanol extract contained secondary metabolite compounds namely alkaloids, flavonoids, steroids, phenolics and saponins. By 50 µg/mL, the methanol extract of bugenvil flower can inhibit α-glucosidase activity with a percent inhibition value of 79.42% while acarbose as a positive control in this study exhibited antidiabetic activity against α-glucosidase of 99.30% at a concentration of 0.00006 µg/mL.
SKRINING FITOKIMIA DAN UJI TOKSISITAS MENGGUNAKAN BRINE SHRIMP LETHALITY TEST (BSLT) DARI EKSTRAK DIKLOROMETANA RIMPANG TEMU KUNCI (Boesenbergia rotunda) Jonathan, Jonathan; Ruga, Ritbey; Hairani, Rita
JURNAL ATOMIK Vol 9 No 2 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i2.1407

Abstract

The rhizome of Boesenbergia rotunda (temu kunci) is one of medicinal plants having potential for medicinal, supplementary food and drink due to its biological activities. The aims of this research are to identified the secondary metabolite compounds present in the dichlorometane extract of finger-root rhizomes through phytochemical screening using thin layer chromatography (TLC) method and to investigated its toxicity against Artemia salina L. shrimp larvae by using Brine Shrime Lethality Test (BSLT). The result of phytochemical analysis showed that the dichloromethane extract contains secondary metabolite compounds including flavonoids, phenolics and triterpenoids while the toxicity test of the extract showed its LC50 value of 303.68 µg/mL. It was indicated that the extract could be classified as toxic.
AKTIVITAS ANTIOKSIDAN TUMBUHAN GENUS MANGIFERA DENGAN METODE DPPH (1,1-diphenyl-2-picrylhydrazyl) : MINI REVIEW Jannah, Nurul; Hairani, Rita; Marliana, Eva
JURNAL ATOMIK Vol 9 No 2 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i2.1394

Abstract

Mangifera is a genus of the Anacardiaceae family of mangoes spread across Sumatra, Kalimantan, Java, and Bali. Several species of the genus Mangifera have been extensively researched on phytochemistry and antioxidant activity using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The study explains that several species of the genus Mangifera contain secondary metabolite compounds, such as flavonoids, phenolics, tannins, saponins, alkaloids, triterpenoids, and quinones. The results of several studies explain that the Mangifera genus has antioxidant activity with an inhibitory concentration (IC50) value generally <50 ppm, which is a strong category, so it has the potential to be an antioxidant. Keywords : Mangifera, phytochemical screening, antioxidant activity
ULASAN KANDUNGAN METABOLIT SEKUNDER DAN KAJIAN BIOAKTIVITAS PADA RUMPUT TEKI (Cyperus rotundus L.) Nurbah, Sahriana Putri; Sitorus, Saibun; Hairani, Rita
PROSIDING SEMINAR KIMIA Vol 3 No 1 (2024): Prosiding SNK 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Nutgrass (Cyperus rotundus L.) is one of the Cyperaceae family plants which is this plant belongs to weed. However, it is often used by the Chinese people as a traditional medicine. This review aimed to determine the bioactivity of nutgrass based on their secondary metabolite content. This review was carried out by Literature Review Article method from various journals through Google Scholar and Science Direct. The results of this review indicated that nutgrass has important bioactivities such as antioxidants, antidiabetic, anti-inflammatory, anticancer and antibacterial. Based on the review of those articles, it can be concluded that nutgrass has several important potency for human health to be further studied. Keywords: Cyperus rotundus L, Bioactivity, Secondary Metabolites
ISOLATION OF LIPASE PRODUCING BACTERIA FROM HOT SPRINGS OF LONG KALI Alawiyah, Dessy Noor; Astuti, Winni; Hairani, Rita
JURNAL ATOMIK Vol 6 No 1 (2021)
Publisher : Jurusan Kimia FMIPA UNMUL

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Abstract

Isolasi bakteri penghasil lipase dari sumber air panas Long Kali dilakukan dengan menyeleksi koloni bakteri pada media Nutrient Agar (NA) yang mengandung Rhodamin B dan minyak zaitun. Hasil isolasi menunjukkan 5 dari 14 isolat bakteri mampu menghasilkan lipase. lima isolat tersebut diuji aktivitas lipase dengan metode titrimetri, isolat dengan kode 14 memiliki aktivitas tertinggi dengan aktivitas 2,20 Unit/mL.
AKTIVITAS ANTI-Staphylococcal SECARA IN VITRO EKSTRAK DIKLOROMETANA DARI RIMPANG TEMU KUNCI (Boesenbergia rotunda) TERHADAP Staphylococcus aureus ATCC 25923 Matutu, Deni Ari; Hairani, Rita; Ruga, Ritbey
JURNAL ATOMIK Vol 10 No 1 (2025)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v10i1.1404

Abstract

The rhizome of temu kunci (Boesenbergia rotunda) is one of the plants used by the local people in Indonesia as a traditional medicine. This study aimed to identify the secondary metabolite compounds contained in the dichloromethane extract with phytochemical screening and investigate its antibacterial activity against test bacteria Staphylococcus aureus ATTC 25923 was carried out by agar diffusion method with modification where tetracycline as a positive control and ethanol as a negative control. The phytochemical screening showed the dichloromethane extract contains secondary metabolites such as alkaloids, flavonoids, phenolics and triterpenoids. With 1 mg/mL of dichloromethane extract revealed its antibacterial activity against S. aureus with inhibitory zone value of 15.0 ± 0.0 mm while its MIC value of the extract was 0.031 ± 0.0 mg/mL toward of tested bacteria. In addition, tetracycline as a positive control at 0.5 μg/mL exhibited its antibacterial potential with an inhibitory zone value of 22.0 ± 0.0 mm and its MIC value of 0.016 ± 0.577 µg/mL.
Co-Authors Alawiyah, Dessy Noor Aman Sentosa Panggabean Ayu Mellyanti Daniel Djihan Ryn Pratiwi, Djihan Ryn Ersanto, Tri Edi Erwin Erwin Erwin Erwin Eva Marliana Eva Marliana, Eva Indra Masmur Jonathan Jonathan Magdaleni, Agustina Rahayu Masmur, Hestina Matutu, Deni Ari Medi Hendra Medi Hendra, Medi Nurbah, Sahriana Putri Nurul Jannah Puspitasari, Intan Dessy Ramadhan, Aulia Rika anggraini Ritbey Ruga Ritson Purba, Ritson Ruga, Ritbey Saibun Sitorus Saleh, Chairul Sjarif Ismail Soerja Koesnarpadi Subur P Pasaribu Supratman, Rafif Ghanaifalah Dely Swandari Paramita T, Nurnaningsi Teguh Wirawan Teguh Wirawan, Teguh Tri Edi Ersanto Wardani, M. Rizky Winni Astuti Winni Astuti, Winni Yuwinda Cindy Elisabet Panggabean