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All Journal Abdimas Mandalika Jurnal Medika Farmaka
Oktapiani, Selvia
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Education Environmental Science Immunology & microbiology

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Review: Potensi Spesies Croton Sebagai Anti-HIV Hanifah, Nidaa; Dila Ayu Apsari, Ratna; Anis Jungjunan, Repita; Muhammad Wahid Fadhilah, Reyhan; Virginia Kiik, Rosa; Oktapiani, Selvia; Maria Ina Ose Tapowolo, Selviana; Musdalifah, Siti; Pudjiastuty, Tiara; Septiani, Yuni
Jurnal Medika Farmaka Vol 3 No 1 (2025): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v3i1.60

Abstract

Introduction: HIV is a retrovirus that attacks the immune system and can develop into AIDS if not treated. Drug resistance and therapy limitations are major challenges. The genus Croton (Euphorbiaceae) has potential as a source of anti-HIV compounds, with species such as C. megalocarpus, C. dichogamus, and C. oligandrus capable of inhibiting reverse transcriptase and reactivating latent viruses. Methods: This narrative review, analyzes the literature from 2020–2024. Results: Studies show that bioactive compounds from Croton, particularly diterpenoids and flavonoids, have anti-HIV activity through the inhibition of reverse transcriptase and reactivation of latent viruses. Conclusion: The genus Croton has the potential to be a new source of anti-HIV drugs. With the increasing drug resistance, the development of bioactive compounds from Croton could become a promising therapeutic alternative.Keywords: Croton, anti-VIV, natural compound
Review Artikel Pengembangan Penyalutan Tablet Terhadap Kualitas dan Mekanisme Obat: Review Artikel Pengembangan Penyalutan Tablet Terhadap Kualitas dan Mekanisme Obat Pratama, Reza; Rodinah, Ina; Bokotei, Martini; willis, Hawa; Oktapiani, Selvia; Hostati, Febri; Pahlevi, Muhammad Reza
Jurnal Medika Farmaka Vol 2 No 2 (2024): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v2i2.24

Abstract

Introduction: Tablets are the most popular dosage form to be given to patients, with most of the tablets produced having a thin layer of film coating. Method: used in studying the development of tablets with coating is Systematic Literature Review (SLR). Result: There are various methods to reduce product failure and development costs. Real-time assessment of coating quality is essential, especially in automated production. Therefore, the implementation of PAT is the latest trend for more effective monitoring and control of pharmaceutical unit operations. In addition to PAT, computational modeling is also actively used to aid in understanding, prediction, and problem-solving in film coating operations. Conclusion. Based on the journal review, it can be concluded that coating can be done for various purposes, ranging from improving the physical properties of tablets to improving the stability of tablets in the tablet manufacturing process. Keywords: tablet coating, tablet development, coating development, tablet coating development.
Pemberdayaan Masyarakat Desa Buntalan Klaten Tengah melalui Edukasi Kesehatan Jamilatun, Makhabbah; Indah Lukito, Pradea; Oktapiani, Selvia
Abdimas Mandalika Vol 4, No 1 (2024): Agustus
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/am.v4i1.25016

Abstract

Abstract: Non-communicable diseases (NCDs) are related to lifestyle. Efforts are needed to overcome the increasing prevalence of NCDs, including providing motivation and mobilizing people to improve their lifestyle patterns and lifestyles for the better. Based on this, Community Empowerment in Buntalan Village, Central Klaten was carried out through Health Education, to increase community awareness of adopting a healthy lifestyle. The activity method used in this community service activity is health education which includes the dangers of artificial coloring in food and the dangers of cosmetics containing mercury. Apart from education, people are encouraged to drink herbal medicine, eat fruit, and have healthy behavior such as wearing masks and washing their hands properly. As a result of this activity, the community in Buntalan Village, Central Klaten became more aware of the importance of adopting a healthy lifestyle to reduce the increase in non-communicable diseases. This community service activity, can be used to motivate the community to get used to a healthy lifestyle, so that it can improve the health status of the community, especially the community in Buntalan Village, Central Klaten.Abstrak: Penyakit tidak menular (PTM) berkaitan dengan pola hidup. Diperlukan upaya untuk mengatasi peningkatan prevalensi PTM, antara lain dengan memberikan motivasi dan menggerakkan masyarakat untuk memperbaiki pola dan gaya hidup menjadi lebih baik. Berdasarkan hal tersebut, dilakukan Pemberdayaan Masyarakat Desa Buntalan Klaten Tengah melalui Edukasi Kesehatan, dengan tujuan untuk meningkatkan kesadaran masyarakat dalam menerapkan pola hidup sehat. Metode kegiatan yang digunakan dalam kegiatan pengabdian masyarakat ini adalah edukasi kesehatan yang meliputi bahaya pewarna buatan pada makanan dan bahaya kosmetik bermerkuri. Selain edukasi, masyarakat juga digerakkan untuk minum jamu, makan buah, serta perilaku sehat seperti menggunakan masker dan cuci tangan dengan benar. Hasil kegiatan ini, masyarakat di Desa Buntalan Klaten Tengah menjadi lebih paham akan pentingnya menerapkan pola hidup sehat sebagai upaya untuk mengurangi peningkatan penyakit tidak menular. Dengan adanya kegiatan pengabdian kepada masyarakat ini dapat digunakan untuk memotivasi masyarakat dalam membiasakan pola hidup sehat, sehingga dapat meningkatkan derajat kesehatan masyarakat khususnya masyarakat di Desa Buntalan Klaten Tengah.
Co-Authors Anis Jungjunan, Repita Bokotei, Martini Dila Ayu Apsari, Ratna Hanifah, Nidaa Hostati, Febri Indah Lukito, Pradea Makhabbah Jamilatun Maria Ina Ose Tapowolo, Selviana Muhammad Reza Pahlevi Muhammad Wahid Fadhilah, Reyhan Musdalifah, Siti Pratama, Reza Pudjiastuty, Tiara Rodinah, Ina Septiani, Yuni Virginia Kiik, Rosa willis, Hawa