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All Journal Majalah Obat Tradisional Indonesian Journal of Environment and Disaster
Andriyani, Della
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Earth & Planetary Sciences Environmental Science Health Professions Medicine & Pharmacology Public Health

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The Effect of Cultivation Site Altitudes on the Quality Parameters of Meniran (Phylanthus niruri L.) Wahyuni, Dinar Sari C.; Pangestika, Maya Widia; Andriyani, Della; Rinanto, Yudi; Fatimah, Siti
Majalah Obat Tradisional Vol 28, No 3 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.72163

Abstract

Meniran (Phyllanthus niruri L.) is known as a medicinal plant for immunomodulatory, hypoglycemic, diuretic treatment, and kidney disorders. It has phenolic and flavonoid as the active compounds. Several commercial products utilize meniran as the main ingredient for immunomodulators. However, the standard raw material for production has not been well reported. The study aimed to standardize the quality of meniran’s raw materials from different locations and altitudes. The phenolic compounds as the active component and their antioxidant activity were further studied. The raw materials were collected from Sukoharjo, Jember, and Karanganyar which are located from 104 masl, 243 masl, and 722 masl. The specific and non-specific standardization based on Indonesian Herbal Pharmacopoeia were investigated. The antioxidant activity was investigated. It resulted in the specific and non-specific parameters that were according to standard except for the acid soluble ash test from the Jember sample which was much higher (6.333% ± 0.969) than the standard (<1.2%). In addition, the flavonoid (1.529 ± 0.167%w/w) and phenolic (1.65 ± 0.006 %w/w) content showed that the sample collected from Jember was significantly higher than other locations. However, the strongest antioxidant activity was in the sample collected from Sukoharjo (IC50 101.84μg/mL). On the other hand, there was no correlation between the total flavonoid and the total phenolic to antioxidant activity in this plant. It suggested that the antioxidant activity in these plants did not depend on the flavonoid and phenolic compounds. In conclusion, the raw material of meniran (Phyllanthus niruri L.) collected from 3 different altitudes showed the quality of herbal medicine of mainly non-specific parameters and met the requirements of Indonesian Herbal Pharmacopoeia. The total phenolic and flavonoid as the active substances varied through all 3 different altitudes. It was in line with the antioxidant activity which varied to all 3 different altitudes due to the phytochemical profile variety.
PARTISIPASI MASYARAKAT DALAM PROGRAM DESA TANGGUH BENCANA DI DESA BANARAN KABUPATEN PULUNG KABUPATEN PONOROGO TAHUN 2021 Andriyani, Della; Ahmad; Ajar, Seno Budhi
Indonesian Journal of Environment and Disaster Vol. 1 No. 2 (2022): Indonesian Journal of Environment and Disaster
Publisher : Disaster Research Center, Universitas Sebelas Maret, Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/ijed.v1i2.440

Abstract

Penelitian ini menjelaskan bahwa (1) Tingkat partisipasi masyarakat dalam kegiatan penanaman pohon di daerah longsor untuk Desa Krajan dan Desa Gondangsari tergolong rendah dan untuk Desa Tangkil dan Desa Sooro tergolong tinggi. Tingkat partisipasi masyarakat dalam kegiatan sosialisasi daerah rawan longsor dan pelatihan kebencanaan di Desa Krajan, Desa Tangkil, dan Desa Sooro tergolong tinggi dan untuk Desa Gondangsari tergolong rendah. (2) Ada empat bentuk partisipasi masyarakat dalam program Desa Tangguh Bencana di Desa Banaran, yaitu bentuk partisipasi ide/pikiran, bentuk partisipasi harta, bentuk partisipasi tenaga kerja, dan bentuk partisipasi keterampilan. Bentuk partisipasi masyarakat dalam kegiatan penanaman pohon di wilayah terdampak longsor yang memiliki bentuk partisipasi paling lengkap hanya Desa Tangkil dan Desa Sooro. Bentuk partisipasi masyarakat dalam kegiatan sosialisasi daerah rawan longsor yang memiliki bentuk partisipasi paling lengkap hanya Desa Krajan, Desa Tangkil, dan Desa Sooro, sedangkan bentuk partisipasi masyarakat dalam kegiatan pelatihan kebencanaan yang memiliki bentuk partisipasi paling lengkap hanya Desa Krajan
Co-Authors Ahmad ajar, seno budhi Pangestika, Maya Widia Siti Fatimah Wahyuni, Dinar Sari C. Yudi Rinanto